Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Matthew E, Brown"'
Autor:
Teressa M. Shaw, Samuel T. Dettle, Andres Mejia, Jennifer M. Hayes, Heather A. Simmons, Puja Basu, Jens H. Kuhn, Mitchell D. Ramuta, Cody J. Warren, Peter B. Jahrling, David H. O’Connor, Liupei Huang, Misbah Zaeem, Jiwon Seo, Igor I. Slukvin, Matthew E. Brown, Adam L. Bailey
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 4, Pp 721-731 (2024)
Genetically diverse simian arteriviruses (simarteriviruses) naturally infect geographically and phylogenetically diverse monkeys, and cross-species transmission and emergence are of considerable concern. Characterization of most simarteriviruses beyo
Externí odkaz:
https://doaj.org/article/1a1dc35e15b7408f96c81ee61028b57e
Autor:
Leeana D. Peters, Wen-I Yeh, Juan M. Arnoletti, Matthew E. Brown, Amanda L. Posgai, Clayton E. Mathews, Todd M. Brusko
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The autoimmune pathogenesis of type 1 diabetes (T1D) involves cellular infiltration from innate and adaptive immune subsets into the islets of Langerhans within the pancreas; however, the direct cytotoxic killing of insulin-producing β-cells is thou
Externí odkaz:
https://doaj.org/article/84a0c1b62a9c4bd1bd78d647cf57931b
Autor:
Matthew E. Brown, Leeana D. Peters, Seif R. Hanbali, Juan M. Arnoletti, Lindsey K. Sachs, Kayla Q. Nguyen, Emma B. Carpenter, Howard R. Seay, Christopher A. Fuhrman, Amanda L. Posgai, Melanie R. Shapiro, Todd M. Brusko
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T cell (Treg) adoptive cell therapy (ACT) represents an emerging strategy for restoring immune tolerance in autoimmune diseases. Tregs are commonly purified using a CD4+CD25+CD127lo/- gating strategy, which yields a mixed population: 1) ce
Externí odkaz:
https://doaj.org/article/ee8774329b694e21a6e707bc96062b84
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe pathogenesis of type 1 diabetes (T1D) involves complex genetic susceptibility that impacts pathways regulating host immunity and the target of autoimmune attack, insulin-producing pancreatic β-cells. Interactions between risk variants
Externí odkaz:
https://doaj.org/article/2c1de1e088824b5e93549c26d6f63240
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Graft-vs-host disease (GVHD) is the most common cause of non-relapse mortality following allogeneic hematopoietic stem cell transplantation (HSCT) despite advances in conditioning regimens, HLA genotyping and immune suppression. While murine studies
Externí odkaz:
https://doaj.org/article/3d1b8617dfae413ea2befb82ca647e9b
Autor:
Jue Zhang, Brian E. McIntosh, Bowen Wang, Matthew E. Brown, Mitchell D. Probasco, Sarah Webster, Bret Duffin, Ying Zhou, Lian-Wang Guo, William J. Burlingham, Craig Kent, Michael Ferris, James A. Thomson
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1269-1281 (2019)
Summary: Contractile to synthetic phenotypic switching of smooth muscle cells (SMCs) contributes to stenosis in vascular disease and vascular transplants. To generate more contractile SMCs, we performed a high-throughput differentiation screen using
Externí odkaz:
https://doaj.org/article/a6646e7a3e204df7957e528997a5ae08
Autor:
Jue Zhang, Sarah Webster, Bret Duffin, Matthew N. Bernstein, John Steill, Scott Swanson, Matthew H. Forsberg, Jennifer Bolin, Matthew E. Brown, Aditi Majumder, Christian M. Capitini, Ron Stewart, James A. Thomson, Igor I. Slukvin
Publikováno v:
Stem Cell Reports. 18:585-596
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e948280d5ff2ac5ea259d9d984cc5a0
https://doi.org/10.1016/j.stemcr.2022.12.012
https://doi.org/10.1016/j.stemcr.2022.12.012
Autor:
Matthew E. Brown, Ying Zhou, Brian E. McIntosh, Ian G. Norman, Hannah E. Lou, Mitch Biermann, Jeremy A. Sullivan, Timothy J. Kamp, James A. Thomson, Petros V. Anagnostopoulos, William J. Burlingham
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1175-1183 (2018)
Summary: Here, we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus and umbilical cord blood hematopoietic stem cells (HSCs). Conventional humanized mouse models are made by engrafti
Externí odkaz:
https://doaj.org/article/081f57c2cd484249a05a76cb93c1caa6
Autor:
John P. Maufort, Jacqueline S. Israel, Matthew E. Brown, Steve J. Kempton, Nicholas J. Albano, Weifeng Zeng, Laurel E. Kelnhofer, Matthew R. Reynolds, Elizabeth S. Perrin, Ruston J. Sanchez, Igor I. Slukvin, James A. Thomson, Samuel O. Poore
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 15 (2019)
Background Arterial bypass and interposition grafts are used routinely across multiple surgical subspecialties. Current options include both autologous and synthetic materials; however, each graft presents specific limitations. Engineering artificial
Externí odkaz:
https://doaj.org/article/20310335764c4e399b3cd022b68a40c5
Autor:
Christopher J, Little, William J, Haynes, Liupei, Huang, Cross M, Daffada, Bryce K, Wolfe, Elizabeth, Perrin, John A, Simpson, Jenna A, Kropp Schmidt, Hayly M, Hinkle, Logan T, Keding, Ryan T, Behrens, David T, Evans, Dixon B, Kaufman, James A, Thomson, Thaddeus G, Golos, Matthew E, Brown
Publikováno v:
Journal of Leukocyte Biology. 112:759-769
Nonhuman primates (NHPs) represent one of the most important models for preclinical studies of novel biomedical interventions. In contrast with small animal models, however, widespread utilization of NHPs is restricted by cost, logistics, and availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a058c10dd4beb268f57db8d9c8ee856
https://doi.org/10.1002/jlb.5ta0921-481rr
https://doi.org/10.1002/jlb.5ta0921-481rr