Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Matthew E, Barton"'
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738-P: Proposed Biosimilar Gan & Lee Insulin Aspart (GL-ASP) Shows Pharmacokinetic (PK) and Pharmacodynamic (PD) Bioequivalence (BE) to U.S.- and EU-Licensed Insulin Aspart (ASP)
Autor: Tim Heise, Michael G. Wilson, Matthew E. Barton, Eric Zijlstra, Leona Plum-Moerschel, Ernestos H. Uhrmacher, Jia Lu
Publikováno v: Diabetes. 70
This randomized, double-blind, three-way crossover trial (NCT04237129) investigated the PK and PD properties of GL-ASP, a proposed biosimilar ASP by Gan & Lee, US licensed Novolog® and EU authorized NovoRapid® (US-ASP and EU-ASP) in 36 healthy male
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d8b7a69fb1e2074dc7c7235f62370d0
https://doi.org/10.2337/db21-738-p
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Total body skeletal muscle mass estimated by magnetic resonance imaging and creatine (methyl‐d3) dilution in athletes
Autor: Tessa Eleri Morris-Paterson, Michael S. Leonard, Owen Carmichael, Matthew E. Barton, Stephen D. R. Harridge, Ken A. van Someren, Ram R. Miller, Stephen A. Stimpson
Publikováno v: Morris-Paterson, T E, Stimpson, S A, Miller, R R, Barton, M E, Leonard, M S, Carmichael, O, van Someren, K A & Harridge, S D R 2019, ' Total body skeletal muscle mass estimated by Magnetic Resonance Imaging and creatine ( methyl-d3 ) dilution in athletes ', Scandinavian Journal of Medicine and Science in Sports . https://doi.org/10.1111/sms.13585
Creatine dilution (D 3-cr) is a technique for estimating total skeletal muscle mass (SMM) with practical utility, but has not been applied in athletic populations where body composition may differ to that in the normal population. This study aimed to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a00eb28d0688040645d8c14431c5883
https://doi.org/10.1111/sms.13585
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7
The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying
Autor: Duncan Richards, Jan Tack, Kimberley Hacquoil, Per M. Hellström, Lakshmi Vasist Johnson, George E. Dukes, Matthew E. Barton, David H. Alpers, Gareth J. Sanger
Publikováno v: British Journal of Pharmacology. 173:1768-1777
Background and Purpose Here we have investigated the pharmacokinetics, pharmacodynamics and safety of single doses of camicinal in type 1 diabetes mellitus (T1DM) patients with a history of slow gastric emptying with symptoms consistent with gastropa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3d766e0dab2de06bf7a5a3230a5c4a9
https://doi.org/10.1111/bph.13475
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Relative Bioavailability of a Single Dose of Belimumab Administered Subcutaneously by Prefilled Syringe or Autoinjector in Healthy Subjects
Autor: N.L. Fox, Matthew E. Barton, Herbert Struemper, Joseph Fire, David Gordon, Thomas Murtaugh, David M. Roth, Jane Gilbert, J. Groark
Publikováno v: Clinical Pharmacology in Drug Development
Intravenous belimumab is approved for the treatment of systemic lupus erythematosus; subcutaneous self‐administration would enable greater patient access. This study assessed relative bioavailability, tolerability, and safety of 1 subcutaneous dose
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c018e810f016b53a7fa13b4f25f8e7
https://doi.org/10.1002/cpdd.219
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A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease
Autor: George E. Dukes, Dag Nyholm, Bhopinder K. Sarai, Lakshmi S. Vasist, Sarah L Marrinan, Matthew E. Barton, Duncan Richards, Per M. Hellström, David J. Burn, Tal Otiker, Rachel A. Gibson
Publikováno v: Movement Disorders
Background: Delayed gastric emptying may impairʟ-dopa absorption, contributing to motor fluctuations. We evaluated the effect of camicinal (GSK962040), a gastroprokinetic, on the absorption ofʟ-dopa and symptoms of PD. Methods: Phase II, double‐b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab00873a359c7a1fc53380d59b6b9ce
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343107
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Nutrition Adequacy Therapeutic Enhancement in the Critically Ill: A Randomized Double-Blind, Placebo-Controlled Trial of the Motilin Receptor Agonist Camicinal (GSK962040): The NUTRIATE Study
Autor: Xiaoling Ou, Adam M. Deane, Lakshmi S. Vasist, Henry T. Stelfox, George E. Dukes, Kimberley Hacquoil, Matthew E. Barton, Daren K. Heyland, Andrew G. Day, Duncan Richards, Marianne J. Chapman, Sangeeta Mehta, Francois Lamontagne, David Neil
Publikováno v: JPEN. Journal of parenteral and enteral nutrition. 42(5)
Background Camicinal is a novel, nonmacrolide, motilin receptor agonist that accelerates gastric emptying in critically ill patients with established feed intolerance. The primary question was whether the preemptive administration of camicinal increa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ef847941b157cc29e542cea4a6ba08
https://pubmed.ncbi.nlm.nih.gov/29957868
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