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pro vyhledávání: '"Matthew Donald Taves"'
Publikováno v:
The Journal of Immunology. 202:53.12-53.12
Thymocyte selection is critical for generation of a competent and tolerant T cell repertoire, and glucocorticoids (GCs) antagonize T cell receptor (TCR) signaling and negative selection to strengthen the TCR repertoire. While circulating GCs from the
Autor:
Matthew Donald Taves, Paul R Mittelstadt, Anastasia M Korol, Jordan E Hamden, Ninan Abraham, Kiran K Soma, Jonathan D Ashwell
Publikováno v:
The Journal of Immunology. 198:202.1-202.1
Thymocyte positive and negative selection are critical for generation of a competent and self-tolerant T cell repertoire. Glucocorticoids (GCs) protect thymocytes from T cell receptor (TCR)-induced death, and thymocyte-specific GC receptor (GR) delet