Zobrazeno 1 - 3
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pro vyhledávání: '"Matthew Diamandas"'
Biaryl and heterobiaryl-containing cyclic peptides represent promising scaffolds in the development of bioactive molecules. The incorporation of heterobiaryl motifs continues to pose synthetic challenges, which is partially due to the difficulties in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6dba7a51efc35c43b195aac718e9a68
https://doi.org/10.26434/chemrxiv-2023-frwx6
https://doi.org/10.26434/chemrxiv-2023-frwx6
Publikováno v:
The Journal of Organic Chemistry. 84:15476-15485
The aminohydroxylation of various alkenes using FmocNHCl as a nitrogen source is reported. In general, in the absence of a ligand, the reaction provided racemic Fmoc-protected amino alcohols with excellent regioselectivity but in low to moderate yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5965b9521fcb615e000f65d5a3d8a0
https://doi.org/10.1021/acs.joc.9b02491
https://doi.org/10.1021/acs.joc.9b02491
Publikováno v:
Organic letters. 23(8)
A new approach to the synthesis of Z-dehydrotryptophan (ΔTrp) peptides is described. This approach uses Fmoc-β-HOTrp(Boc)(TBS)-OH as a building block, which is readily prepared in high yield and incorporated into peptides using solid-phase Fmoc che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8ce6b51464eaa7ff7a3d8e4aa861bd
https://pubmed.ncbi.nlm.nih.gov/33769052
https://pubmed.ncbi.nlm.nih.gov/33769052