Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Matthew D. Whim"'
Publikováno v:
Endocrinology
During fasting, increased sympathoadrenal activity leads to epinephrine release and multiple forms of plasticity within the adrenal medulla including an increase in the strength of the preganglionic → chromaffin cell synapse and elevated levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2802ed31c0fd78b8af49f59cf91990
https://pubmed.ncbi.nlm.nih.gov/35595517
https://pubmed.ncbi.nlm.nih.gov/35595517
Publikováno v:
Journal of Clinical Investigation. 128:3866-3871
Hypoglycemia activates the counterregulatory response (CRR), a neural-endocrine reflex that restores euglycemia. Although effective if occasionally activated, repeated induction of the CRR leads to a decline in responsiveness and prolonged exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a8dd09eb5bc40f5d75b3a1ac324469
https://doi.org/10.1172/jci91921
https://doi.org/10.1172/jci91921
Autor:
Matthew D Whim
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19478 (2011)
In addition to polypeptide hormones, pancreatic endocrine cells synthesize a variety of bioactive molecules including classical transmitters and neuropeptides. While these co-transmitters are thought to play a role in regulating hormone release littl
Externí odkaz:
https://doaj.org/article/9b23e898a3e640be8eec0e82322d0535
Publikováno v:
Endocrinology. 158:2572-2584
Fasting evokes a homeostatic response that maintains circulating levels of energy-rich metabolites and increases the drive to eat. Centrally, this reflex activates a small population of hypothalamic neurons that are characterized by the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5431b56bd0ce7ec9c54b953f3bc09b49
https://doi.org/10.1210/en.2016-1268
https://doi.org/10.1210/en.2016-1268
Autor:
Qian Wang, Matthew D. Whim
Publikováno v:
Journal of Neurochemistry. 125:16-25
Neuropeptide Y is a co-transmitter that is synthesized by chromaffin cells in the adrenal medulla. During the fight-or-flight response these cells release NPY in addition to epinephrine and norepinephrine. Following the stress-induced reflex, the lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68dc71b6285f6fb9154b4f80acedb43
https://doi.org/10.1111/jnc.12150
https://doi.org/10.1111/jnc.12150
Publikováno v:
Proceedings of the National Academy of Sciences. 113
During fasting, activation of the counter-regulatory response (CRR) prevents hypoglycemia. A major effector arm is the autonomic nervous system that controls epinephrine release from adrenal chromaffin cells and, consequently, hepatic glucose product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fa87b4815b3a032dc2716a7c9244a4
https://doi.org/10.1073/pnas.1517275113
https://doi.org/10.1073/pnas.1517275113
Publikováno v:
The Journal of Neuroscience. 28:14428-14434
A single nucleotide polymorphism (SNP) in the neuropeptide Y gene has been associated with elevated serum lipid levels and cardiovascular disease. The polymorphism (T1128C) changes the seventh amino acid in the prohormone from leucine to proline. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44814d4cafe9864e6ba9f17c50aff6b9
https://doi.org/10.1523/jneurosci.0343-08.2008
https://doi.org/10.1523/jneurosci.0343-08.2008
Autor:
Matthew D. Whim, Prabhu Ramamoorthy
Publikováno v:
The Journal of Neuroscience. 28:13815-13827
It is becoming clear that astrocytes are active participants in synaptic functioning and exhibit properties, such as the secretion of classical transmitters, previously thought to be exclusively neuronal. Whether these similarities extend to the rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe7ab65f44b33bcd51931941b54662e
https://doi.org/10.1523/jneurosci.5361-07.2008
https://doi.org/10.1523/jneurosci.5361-07.2008
Autor:
Christian A. A. von Hehn, Ping Song, Li Gan, Bo Yang, Rooma Desai, Leonard K. Kaczmarek, Arin Bhattacharjee, Matthew D. Whim
Publikováno v:
Hearing Research. 206:133-145
The firing patterns of neurons in central auditory pathways encode specific features of sound stimuli, such as frequency, intensity and localization in space. The generation of the appropriate pattern depends, to a major extent, on the properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c670212e381195da144fe2689f3de3
https://doi.org/10.1016/j.heares.2004.11.023
https://doi.org/10.1016/j.heares.2004.11.023
Publikováno v:
The Journal of Physiology. 535:647-662
1. When buccal neuron B2 of Aplysia californica is co-cultured with sensory neurons (SNs), slow peptidergic synapses are formed. When B2 is co-cultured with neurons B3 or B6, fast cholinergic synapses are formed. 2. Patch pipettes were used to voltag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86b9f5b7eb03d807b83319a99d05322
https://doi.org/10.1111/j.1469-7793.2001.00647.x
https://doi.org/10.1111/j.1469-7793.2001.00647.x