Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Matthew D. Snape"'
Autor:
Gu-Lung Lin, Simon B. Drysdale, Matthew D. Snape, Daniel O’Connor, Anthony Brown, George MacIntyre-Cockett, Esther Mellado-Gomez, Mariateresa de Cesare, M. Azim Ansari, David Bonsall, James E. Bray, Keith A. Jolley, Rory Bowden, Jeroen Aerssens, Louis Bont, Peter J. M. Openshaw, Federico Martinon-Torres, Harish Nair, Tanya Golubchik, Andrew J. Pollard, RESCEU Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Respiratory syncytial virus (RSV) is the leading cause of hospitalisation for respiratory infection in young children. RSV disease severity is known to be age-dependent and highest in young infants, but other correlates of severity, particul
Externí odkaz:
https://doaj.org/article/cf0de01a2b3540ecb73b7d2b7c6334c0
Autor:
Dmitri Kazmin, Elizabeth A. Clutterbuck, Giorgio Napolitani, Amanda L. Wilkins, Andrea Tarlton, Amber J. Thompson, Emmanuele Montomoli, Guilia Lapini, Smiti Bihari, Rachel White, Claire Jones, Matthew D. Snape, Ushma Galal, Ly-Mee Yu, Rino Rappuoli, Giuseppe Del Giudice, Andrew J. Pollard, Bali Pulendran
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we performed a systems-level analysis o
Externí odkaz:
https://doaj.org/article/e08bd682474d4f25b313914b68f1c30c
Autor:
Helen Ratcliffe, Karen S. Tiley, Stephanie Longet, Claire Tonry, Cathal Roarty, Chris Watson, Gayatri Amirthalingam, Iason Vichos, Ella Morey, Naomi L. Douglas, Spyridoula Marinou, Emma Plested, Parvinder K. Aley, Eva Galiza, Saul N. Faust, Stephen Hughes, Clare Murray, Marion R. Roderick, Fiona Shackley, Sam Oddie, Tim W.R. Lee, David P.J. Turner, Mala Raman, Stephen Owens, Paul J. Turner, Helen Cockerill, Jamie Lopez Bernal, Samreen Ijaz, John Poh, Justin Shute, Ezra Linley, Ray Borrow, Katja Hoschler, Kevin E. Brown, Miles W. Carroll, Paul Klenerman, Susanna J. Dunachie, Mary Ramsay, Merryn Voysey, Thomas Waterfield, Matthew D. Snape
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108500- (2023)
Summary: SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalization. Why this is so remains unclear. Here we explore the potential for protection due to pre-existing cross-reactive s
Externí odkaz:
https://doaj.org/article/d001144b1e95484bbbfeb1677546d166
Autor:
Katharina Warncke, Andreas Weiss, Peter Achenbach, Thekla von dem Berge, Reinhard Berner, Kristina Casteels, Lidia Groele, Konstantinos Hatzikotoulas, Angela Hommel, Olga Kordonouri, Helena Elding Larsson, Markus Lundgren, Benjamin A. Marcus, Matthew D. Snape, Agnieszka Szypowska, John A. Todd, Ezio Bonifacio, Anette-G. Ziegler, for the GPPAD and POInT Study Groups
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell death. The autoimmunity is considered silent without metabolic consequences until late prec
Externí odkaz:
https://doaj.org/article/5d1e339b0649403baa1541e2fd952875
Autor:
Gu-Lung Lin, Simon B. Drysdale, Matthew D. Snape, Daniel O’Connor, Anthony Brown, George MacIntyre-Cockett, Esther Mellado-Gomez, Mariateresa de Cesare, David Bonsall, M. Azim Ansari, Deniz Öner, Jeroen Aerssens, Christopher Butler, Louis Bont, Peter Openshaw, Federico Martinón-Torres, Harish Nair, Rory Bowden, RESCEU Investigators, Tanya Golubchik, Andrew J. Pollard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Respiratory syncytial virus (RSV) is a common infection in children and older adults but little is known about within-host viral population diversity. Here, the authors perform deep sequencing and find that RSV subgroup B exhibited more diversity tha
Externí odkaz:
https://doaj.org/article/be54b219fed94f08b8ef4d94b0391eab
Autor:
Saul N. Faust, Maguelone Le Roy, Chitsanu Pancharoen, Miguel Angel Rodriguez Weber, Katrina Cathie, Ulrich Behre, Jolanta Bernatoniene, Matthew D. Snape, Klaus Helm, Carlos Eduardo Medina Pech, Ouzama Henry, Carmen Baccarini, Michael Povey, Paul Gillard
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background A new formulation of the live-attenuated varicella vaccine Varilrix (GSK) produced without human serum albumin (HSA) was developed to minimize a theoretical risk of transmission of infectious diseases. A previous study showed that
Externí odkaz:
https://doaj.org/article/19b8f451f93243849ae1c79a7f7b5a2a
Autor:
Bahaa Abu-Raya, Kirsten Maertens, Kathryn M. Edwards, Saad B. Omer, Janet A. Englund, Katie L. Flanagan, Matthew D. Snape, Gayatri Amirthalingam, Elke Leuridan, Pierre Van Damme, Vana Papaevangelou, Odile Launay, Ron Dagan, Magda Campins, Anna Franca Cavaliere, Tiziana Frusca, Sofia Guidi, Miguel O'Ryan, Ulrich Heininger, Tina Tan, Ahmed R. Alsuwaidi, Marco. A. Safadi, Luz M. Vilca, Nasamon Wanlapakorn, Shabir A. Madhi, Michelle L. Giles, Roman Prymula, Shamez Ladhani, Federico Martinón-Torres, Litjen Tan, Lessandra Michelin, Giovanni Scambia, Nicola Principi, Susanna Esposito
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immunization during pregnancy has been recommended in an increasing number of countries. The aim of this strategy is to protect pregnant women and infants from severe infectious disease, morbidity and mortality and is currently limited to tetanus, in
Externí odkaz:
https://doaj.org/article/f927079e5d55464690b5f97616741b26
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 1, Pp 234-244 (2018)
With maternal and infant vaccines against respiratory syncytial virus (RSV) in development, it is timely to consider how the deployment of these vaccines might vary according to local RSV disease seasonality. In temperate regions RSV infection is pre
Externí odkaz:
https://doaj.org/article/d4131916e1114327aa10e64673bd60ac
Autor:
Gu-Lung Lin, Simon B. Drysdale, Matthew D. Snape, Daniel O’Connor, Anthony Brown, George MacIntyre-Cockett, Esther Mellado-Gomez, Mariateresa de Cesare, David Bonsall, M. Azim Ansari, Deniz Öner, Jeroen Aerssens, Christopher Butler, Louis Bont, Peter Openshaw, Federico Martinón-Torres, Harish Nair, Rory Bowden, RESCEU Investigators, Tanya Golubchik, Andrew J. Pollard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/5928a0755bcb41ec973cd1440133dcea
Autor:
Holly B. Bratcher, Charlene M. C. Rodrigues, Adam Finn, Mandy Wootton, J. Claire Cameron, Andrew Smith, Paul Heath, Shamez Ladhani, Matthew D. Snape, Andrew J. Pollard, Richard Cunningham, Raymond Borrow, Caroline Trotter, Stephen J. Gray, Martin C. J. Maiden, Jenny M. MacLennan
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Carriage of Neisseria meningitidis, the meningococcus, is a prerequisite for invasive meningococcal disease (IMD), a potentially devastating infection that disproportionately afflicts infants and children. Humans are the sole known reservoir for the
Externí odkaz:
https://doaj.org/article/4723d9d20b0f4c9a877aabb2fdf4743e