Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Matthew D. Lycas"'
Autor:
Line I. Christiansen, Gemma C. Ventura, Bo Holmqvist, Karoline Aasmul-Olsen, Sandy E. H. Lindholm, Matthew D. Lycas, Yuki Mori, Jan Bojsen-Møller Secher, Douglas G. Burrin, Thomas Thymann, Per T. Sangild, Stanislava Pankratova
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionPreterm infants have increased risk of impaired neurodevelopment to which reduced systemic levels of insulin-like growth factor 1 (IGF-1) in the weeks after birth may play a role. Hence, we hypothesized that postnatal IGF-1 supplementatio
Externí odkaz:
https://doaj.org/article/4d8fb21ad86e4b09b1b873f04f6047ce
Autor:
Eva Baerends, Katia Soud, Jonas Folke, Anna-Kathrine Pedersen, Simon Henmar, Lisa Konrad, Matthew D. Lycas, Yuki Mori, Bente Pakkenberg, David P. D. Woldbye, Oksana Dmytriyeva, Stanislava Pankratova
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disease characterized by the accumulation of aggregated amyloid beta (Aβ) and hyperphosphorylated tau along with a slow decline in cognitive functions. Unlike ad
Externí odkaz:
https://doaj.org/article/8b3657b99e53449abba7ffb4c1079b6d
Autor:
Aske L. Ejdrup, Matthew D. Lycas, Niels Lorenzen, Ainoa Konomi, Freja Herborg, Kenneth L. Madsen, Ulrik Gether
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Full information gained from single-molecule localisation microscopy (SMLM) isn't exploited by current analysis tools. Here the authors report relative enrichment which uses a density-based colocalisation measure for both 2D and 3D SMLM data; they ap
Externí odkaz:
https://doaj.org/article/986dc0cd89724607b8788601c4b1b4b9
Autor:
Rita C. Andersen, Jan H. Schmidt, Joscha Rombach, Matthew D. Lycas, Nikolaj R. Christensen, Viktor K. Lund, Donnie S. Stapleton, Signe S. Pedersen, Mathias A. Olsen, Mikkel Stoklund, Gith Noes-Holt, Tommas T.E. Nielsen, Mark P. Keller, Anna M. Jansen, Rasmus Herlo, Massimo Pietropaolo, Jens B. Simonsen, Ole Kjærulff, Birgitte Holst, Alan D. Attie, Ulrik Gether, Kenneth L. Madsen
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Bin/amphiphysin/Rvs (BAR) domains are positively charged crescent-shaped modules that mediate curvature of negatively charged lipid membranes during remodeling processes. The BAR domain proteins PICK1, ICA69, and the arfaptins have recently been demo
Externí odkaz:
https://doaj.org/article/283f087eadbe4c509ab194ae13855604
Autor:
Freja Herborg, Kathrine L. Jensen, Sasha Tolstoy, Natascha V. Arends, Leonie P. Posselt, Aparna Shekar, Jenny I. Aguilar, Viktor K. Lund, Kevin Erreger, Mattias Rickhag, Matthew D. Lycas, Markus N. Lonsdale, Troels Rahbek-Clemmensen, Andreas T. Sørensen, Amy H. Newman, Annemette Løkkegaard, Ole Kjærulff, Thomas Werge, for the iPSYCH researchers, Lisbeth B. Møller, Heinrich J.G. Matthies, Aurelio Galli, Lena E. Hjermind, Ulrik Gether
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Dysfunctional dopaminergic neurotransmission is central to movement disorders and mental diseases. The dopamine transporter (DAT) regulates extracellular dopamine levels, but the genetic and mechanistic link between DAT function and dopamine-related
Externí odkaz:
https://doaj.org/article/0e76e431d1f8444ba28610dba3786a03
Autor:
Troels Rahbek-Clemmensen, Matthew D. Lycas, Simon Erlendsson, Jacob Eriksen, Mia Apuschkin, Frederik Vilhardt, Trine N. Jørgensen, Freja H. Hansen, Ulrik Gether
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The dopamine transporter (DAT) has a crucial role in the regulation of neurotransmission. Here, the authors use super-resolution imaging to show that DAT clusters into cholesterol-dependent membrane regions that are reversibly regulated by ionotropic
Externí odkaz:
https://doaj.org/article/94adb06557e442279abc6255c4796f9c
Autor:
Aske L. Ejdrup, Joel Wellbourne-Wood, Jakob K. Dreyer, Nina Guldhammer, Matthew D. Lycas, Ulrik Gether, Benjamin J. Hall, Gunnar Sørensen
Publikováno v:
Ejdrup, A L, Wellbourne-Wood, J, Dreyer, J K, Guldhammer, N, Lycas, M D, Gether, U, Hall, B J & Sørensen, G 2023, ' Within-Mice Comparison of Microdialysis and Fiber Photometry-Recorded Dopamine Biosensor during Amphetamine Response ', ACS Chemical Neuroscience, vol. 14, no. 9 . https://doi.org/10.1021/acschemneuro.2c00817
A fundamental concept in neuroscience is the transmission of information between neurons via neurotransmitters, -modulators, and -peptides. For the past decades, the gold standard for measuring neurochemicals in awake animals has been microdialysis (
Autor:
Søren H. Jørgensen, Aske L. Ejdrup, Matthew D. Lycas, Leonie P. Posselt, Kenneth L. Madsen, Lin Tian, Jakob K. Dreyer, Freja Herborg, Andreas T. Sørensen, Ulrik Gether
Publikováno v:
Jørgensen, S H, Ejdrup, A L, Lycas, M D, Posselt, L P, Madsen, K L, Tian, L, Dreyer, J K, Herborg, F, Sørensen, A T & Gether, U 2023, ' Behavioral encoding across timescales by region-specific dopamine dynamics ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 7, e2215230120 . https://doi.org/10.1073/pnas.2215230120
The dorsal (DS) and ventral striatum (VS) receive dopaminergic projections that control motor functions and reward-related behavior. It remains poorly understood how dopa-mine release dynamics across different temporal scales in these regions are cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b4413269dc6b326372ea08486dc19a
https://curis.ku.dk/ws/files/336255717/Fulltext.pdf
https://curis.ku.dk/ws/files/336255717/Fulltext.pdf
Autor:
Aske L. Ejdrup, Joel Wellbourne-Wood, Jakob K. Dreyer, Nina Guldhammer, Matthew D. Lycas, Ulrik Gether, Benjamin J. Hall, Gunnar Sørensen
A fundamental concept in neuroscience is the transmission of information between neurons via neurotransmitters, -modulators, and – peptides. For the past decades the gold standard for measuring neurochemicals in awake animals has been microdialysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d4a9e7b441a3b8115bceddb277ea8e5
https://doi.org/10.1101/2022.10.27.513984
https://doi.org/10.1101/2022.10.27.513984
Autor:
Aske L. Ejdrup, Matthew D. Lycas, Niels Lorenzen, Ainoa Konomi, Freja Herborg, Kenneth L. Madsen, Ulrik Gether
Dual-color single-molecule localization microscopy (SMLM) provides unprecedented possibilities for detailed studies of colocalization of different molecular species in a cell. However, the informational richness of the data is not fully exploited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::768bb6c4588ae69bd83f4b2a10f9a52a
https://doi.org/10.1101/2022.02.08.479535
https://doi.org/10.1101/2022.02.08.479535