Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Matthew D. Hodges"'
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0255715 (2022)
The amyloid cascade hypothesis proposes that excessive accumulation of amyloid beta-peptides is the initiating event in Alzheimer's disease. These neurotoxic peptides are generated from the amyloid precursor protein via sequential cleavage by β- and
Externí odkaz:
https://doaj.org/article/a745a6ae82f842bdb79098b253bbc06c
Autor:
John J. Worthington, Nadin Fathallah, Vinay Shivanna, Fatai S. Oladunni, Luis Martinez-Sobrido, Mohammed A. Rohaim, Lucy H. Jackson-Jones, Jun Gyu Park, Wafaa A. Alhazmi, Jordi B. Torrelles, Renee Escalona, Muhsref Bakri Assas, Pengxiang Chang, Muhammad Munir, Munir Iqbal, Matthew D. Hodges, Jayde Whittingham-Dowd, Abdullah Almilaibary, James Tollitt
Publikováno v:
iScience
iScience, Vol 24, Iss 9, Pp 102941-(2021)
iScience, Vol 24, Iss 9, Pp 102941-(2021)
Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we evaluated a Newcastle disease virus (NDV)-based vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb634834dff6f44fe4d465bc6c96ea9
http://europepmc.org/articles/PMC8332743
http://europepmc.org/articles/PMC8332743
Autor:
Lisa Butler, Ravinder Sodi, Muhammad Munir, Mahmoud Bayoumi, Julianne Vilela, Peter Burkhart, Amy Brown, Irem Sahin, Nouman S. Chaudhry, Mohammad Q. Al-Natour, Emily Clayton, Judy Botham, Wendy Hacking, Roberto M. La Ragione, Mohammed A. Rohaim, Anil Fernando, Elisabeth Shaw, Manar E. Khalifa, Wamadeva Balachandran, Aurore C. Poirier, Mukunthan Tharmakulasingam, Michelle D Bates, Joe Boyce, Matthew D. Hodges, Craig Williams, Hayley Wilkinson, Manoharanehru Branavan, Jayde Whittingham-Dowd
Publikováno v:
Viruses; Volume 12; Issue 9; Pages: 972
Viruses
Viruses, Vol 12, Iss 972, p 972 (2020)
Viruses
Viruses, Vol 12, Iss 972, p 972 (2020)
Until vaccines and effective therapeutics become available, the practical solution to transit safely out of the current coronavirus disease 19 (CoVID-19) lockdown may include the implementation of an effective testing, tracing and tracking system. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dbe97f8c4d80f4b49614152696be79
https://bura.brunel.ac.uk/handle/2438/21820
https://bura.brunel.ac.uk/handle/2438/21820
Autor:
Jack Cameron, Alan D. Shirras, Nikolett Dravecz, Susan J. Broughton, Matthew D. Hodges, Helen Askwith, Zoe Glover
Publikováno v:
Journal of Experimental Biology.
Drosophila Acer (Angiotensin-converting enzyme-related) encodes a member of the angiotensin-converting enzyme (ACE) family of metallopeptidases that in mammals play roles in the endocrine regulation of blood homeostasis. ACE is also expressed in adip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe9dafe8fae0e47493d94774d2638c3
https://doi.org/10.1242/jeb.194332
https://doi.org/10.1242/jeb.194332
Autor:
Zoe, Glover, Matthew D, Hodges, Nikolett, Dravecz, Jack, Cameron, Helen, Askwith, Alan, Shirras, Susan J, Broughton
Publikováno v:
The Journal of experimental biology. 222(Pt 8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87c919df29125e244ca98e76544f8734
https://pubmed.ncbi.nlm.nih.gov/30940674
https://pubmed.ncbi.nlm.nih.gov/30940674
Autor:
Edward T. Parkin, Craig Delury, Susan J. Broughton, Claire Tinker, Samantha Rivers, Matthew D. Hodges
Publikováno v:
Lancaster University-Pure
Aberrant Jagged1-mediated Notch activation is linked to cancer and induces epithelial-to-mesenchymal transition through the repression of E-cadherin transcription. All three proteins are subject to sequential proteolytic events referred to as regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fa0a3d3eb92e1b0dbb198e40161fbd
https://doi.org/10.9734/ijbcrr/2013/3847
https://doi.org/10.9734/ijbcrr/2013/3847
Autor:
Elisabeth J, Shaw, Emily E, Smith, Jayde, Whittingham-Dowd, Matthew D, Hodges, Kathryn J, Else, Rachael J, Rigby
Publikováno v:
Immunity, Inflammation and Disease
Introduction Suppressor of cytokine signaling 3 (SOCS3) is a tumour suppressor, limiting intestinal epithelial cell (IEC) proliferation in acute inflammation, and tumour growth, but little is known regarding its role in mucosal homeostasis. Resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::767df2cd12c2452cdc1ecb8ef323d877
https://pubmed.ncbi.nlm.nih.gov/28508554
https://pubmed.ncbi.nlm.nih.gov/28508554
Autor:
Simon W. Fogarty, Nigel J. Fullwood, Imran I. Patel, Francis Martin, Matthew D. Hodges, Jemma G. Kelly, Adam J. Bentley
Publikováno v:
ACS Nano. 5:9535-9541
We applied surface-enhanced Raman spectroscopy (SERS) to immunolabeled endothelial cells to derive enhanced spectra of the biomolecular makeup of the cellular surface. A two-step immunolabeling protocol with gold-conjugated antibodies coupled with si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2981964b011dec15567dec3da88c66ca
https://doi.org/10.1021/nn202652h
https://doi.org/10.1021/nn202652h
Autor:
Rosemary A. Fisher, Edward S. Newlands, Matthew D. Hodges, Jill Moss, Beverley Burke, Neil J. Sebire, Michael J. Seckl
Publikováno v:
Gynecologic Oncology. 103:642-648
Objectives Previous studies have identified loss of chromosomal regions 7p12–q11.2 and 8p12–p21 in choriocarcinoma suggesting that suppressor genes involved in tumour development may be located within these regions. Our objectives were to refine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569aedfefb80f6dda1bca7be07445066
https://doi.org/10.1016/j.ygyno.2006.04.015
https://doi.org/10.1016/j.ygyno.2006.04.015
Autor:
Joseph J. Boyle, Jennifer A. Smith, Paul R. Cook, Matthew D. Hodges, Rong Dong, Jan Domin, Gurjeet Bhangal, Amy J. Marshall, Penny J. Norsworthy, David J. Evans, Charles D. Pusey, H. Terence Cook, Timothy J. Aitman, Kelly Sheehan-Rooney, Timothy J. Vyse, Cheri Roberton-Lowe, Mark A Duda, Michelle D. Johnson, Jonathan Flint, Sheetal Patel, Jonathan Mangion, Enrico Petretto
Publikováno v:
Nature. 439:851-855
Glomerulonephritis is a kidney inflammation that occurs alone or as part of other conditions, including the autoimmune disorder lupus. A novel mutation has now been identified as the cause of the disease in a rat model. The mutation affects the Fcgr3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6820bf8d0d3dc19b0e10e46bd0b4cab
https://doi.org/10.1038/nature04489
https://doi.org/10.1038/nature04489