Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Matthew D. Hitchings"'
Autor:
Jessica K. Calland, Maiju E. Pesonen, Jai Mehat, Ben Pascoe, David J. Haydon, Jose Lourenco, Barbara Lukasiewicz, Evangelos Mourkas, Matthew D. Hitchings, Roberto M. La Ragione, Philip Hammond, Timothy S. Wallis, Jukka Corander, Samuel K. Sheppard
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Campylobacter is a leading cause of food-borne gastroenteritis worldwide, linked to the consumption of contaminated poultry meat. Targeting this pathogen at source, vaccines for poultry can provide short-term caecal reductions in Campylobact
Externí odkaz:
https://doaj.org/article/8077fca5c18f487b838dfa77bd6a688e
Autor:
Aidan J. Taylor, Koji Yahara, Ben Pascoe, Seungwon Ko, Leonardos Mageiros, Evangelos Mourkas, Jessica K. Calland, Santeri Puranen, Matthew D. Hitchings, Keith A. Jolley, Carolin M. Kobras, Sion Bayliss, Nicola J. Williams, Arnoud H. M. van Vliet, Julian Parkhill, Martin C. J. Maiden, Jukka Corander, Laurence D. Hurst, Daniel Falush, Paul Keim, Xavier Didelot, David J. Kelly, Samuel K. Sheppard
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Recombination of short DNA fragments via horizontal gene transfer (HGT) can introduce beneficial alleles, create genomic disharmony through negative epistasis, and create adaptive gene combinations through positive epistasis. For non-core (a
Externí odkaz:
https://doaj.org/article/b01240a0b60f44418e276da053e1f0fe
Autor:
Amy K. Holt, Arafath K. Najumudeen, Tracey J. Collard, Hao Li, Laura M. Millett, Ashley J. Hoskin, Danny N. Legge, Eleanor M. H. Mortensson, Dustin J. Flanagan, Nicholas Jones, Madhu Kollareddy, Penny Timms, Matthew D. Hitchings, James Cronin, Owen J. Sansom, Ann C. Williams, Emma E. Vincent
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background To support proliferation and survival within a challenging microenvironment, cancer cells must reprogramme their metabolism. As such, targeting cancer cell metabolism is a promising therapeutic avenue. However, identifying tractab
Externí odkaz:
https://doaj.org/article/d2b8ee6de35a474887a1c18cb634d284
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract DNA viruses can exploit host cellular epigenetic processes to their advantage; however, the epigenome status of most DNA viruses remains undetermined. Third generation sequencing technologies allow for the identification of modified nucleoti
Externí odkaz:
https://doaj.org/article/910265d96d3141afb85f3f7de68fb1c2
Autor:
Leonardos Mageiros, Guillaume Méric, Sion C. Bayliss, Johan Pensar, Ben Pascoe, Evangelos Mourkas, Jessica K. Calland, Koji Yahara, Susan Murray, Thomas S. Wilkinson, Lisa K. Williams, Matthew D. Hitchings, Jonathan Porter, Kirsty Kemmett, Edward J. Feil, Keith A. Jolley, Nicola J. Williams, Jukka Corander, Samuel K. Sheppard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
It is unclear how gut-dwelling E. coli bacteria often emerge to cause systemic infection in chickens. Here, Mageiros et al. use population genomics and pangenome-wide association studies to identify genetic elements associated with pathogenicity in a
Externí odkaz:
https://doaj.org/article/84dde1b573d54cc6b0e1ccb662ceff09
Autor:
Prapas Patchanee, Prawitchaya Tanamai, Phacharaporn Tadee, Matthew D. Hitchings, Jessica K. Calland, Samuel K. Sheppard, Dethaloun Meunsene, Ben Pascoe, Pakpoom Tadee
Publikováno v:
PeerJ, Vol 8, p e9700 (2020)
Background Monophasic Salmonella Typhimurium or S. enterica 1,4,[5],12:i:- is among the top five serotypes reported in Thailand. In this study, nineteen monophasic S. Typhimurium from the pig production chain in Chiang Mai and Lamphun provinces durin
Externí odkaz:
https://doaj.org/article/46a3c4e2c69249c0b4bb3f4382604c5a
A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk
Autor:
Elvire Berthenet, Koji Yahara, Kaisa Thorell, Ben Pascoe, Guillaume Meric, Jane M. Mikhail, Lars Engstrand, Helena Enroth, Alain Burette, Francis Megraud, Christine Varon, John C Atherton, Sinead Smith, Thomas S. Wilkinson, Matthew D. Hitchings, Daniel Falush, Samuel K. Sheppard
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Helicobacter pylori are stomach-dwelling bacteria that are present in about 50% of the global population. Infection is asymptomatic in most cases, but it has been associated with gastritis, gastric ulcers and gastric cancer. Epide
Externí odkaz:
https://doaj.org/article/abcb3e36555b4a2083954b07384bc0f7
Autor:
Leonardos Mageiros, Guillaume Méric, Sion C. Bayliss, Johan Pensar, Ben Pascoe, Evangelos Mourkas, Jessica K. Calland, Koji Yahara, Susan Murray, Thomas S. Wilkinson, Lisa K. Williams, Matthew D. Hitchings, Jonathan Porter, Kirsty Kemmett, Edward J. Feil, Keith A. Jolley, Nicola J. Williams, Jukka Corander, Samuel K. Sheppard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22238-5
Externí odkaz:
https://doaj.org/article/6a0997ac8f2c47a19cc67af15e0abc8a
Autor:
Luciana Terra, Paul J. Dyson, Matthew D. Hitchings, Liam Thomas, Alyaa Abdelhameed, Ibrahim M. Banat, Salvatore A. Gazze, Dušica Vujaklija, Paul D. Facey, Lewis W. Francis, Gerry A. Quinn
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
In an effort to stem the rising tide of multi-resistant bacteria, researchers have turned to niche environments in the hope of discovering new varieties of antibiotics. We investigated an ethnopharmacological (cure) from an alkaline/radon soil in the
Externí odkaz:
https://doaj.org/article/ce929ec040b84d6ca08fd83d5546d631
Autor:
Xiaorui Chen, Matthew D. Hitchings, José E. Mendoza, Virginia Balanza, Paul D. Facey, Paul J. Dyson, Pablo Bielza, Ricardo Del Sol
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pest control in agriculture employs diverse strategies, among which the use of predatory insects has steadily increased. The use of several species within the genus Orius in pest control is widely spread, particularly in Mediterranean Europe. Commerc
Externí odkaz:
https://doaj.org/article/32425f3d12cd4708beccd453136e031c