Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Matthew D Weitzman"'
Autor:
Alexander M Price, Robert T Steinbock, Richard Lauman, Matthew Charman, Katharina E Hayer, Namrata Kumar, Edwin Halko, Krystal K Lum, Monica Wei, Angus C Wilson, Benjamin A Garcia, Daniel P Depledge, Matthew D Weitzman
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010797 (2022)
Adenovirus is a common human pathogen that relies on host cell processes for transcription and processing of viral RNA and protein production. Although adenoviral promoters, splice junctions, and polyadenylation sites have been characterized using lo
Externí odkaz:
https://doaj.org/article/eaab36792be84a51a07f2ccdca52cc19
Autor:
Oren Kobiler, Matthew D Weitzman
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007714 (2019)
Externí odkaz:
https://doaj.org/article/f947f04ee10d49389c3e36522764308a
Publikováno v:
eLife, Vol 3 (2014)
Long INterspersed Element-1 (LINE-1 or L1) retrotransposition poses a mutagenic threat to human genomes. Human cells have therefore evolved strategies to regulate L1 retrotransposition. The APOBEC3 (A3) gene family consists of seven enzymes that cata
Externí odkaz:
https://doaj.org/article/8bbe9e396ac249a28c44c58809b5568b
Autor:
Justine Marsolier, Sandra Pineau, Souhila Medjkane, Martine Perichon, Qinyan Yin, Erik Flemington, Matthew D Weitzman, Jonathan B Weitzman
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003222 (2013)
The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in parasite-induced transformation phenotypes. Tumour progression is a multistep process, yet 'oncoge
Externí odkaz:
https://doaj.org/article/a8c1777ebe0249a7b91004fef29fe465
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002084 (2011)
Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. During the initial stages of HSV-1 infection, novel sub-nuclear structures containing these ND10 proteins form in association with inco
Externí odkaz:
https://doaj.org/article/412315e83fb548c8a9c7e34dd3cd5c76
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001141 (2010)
Infection by DNA viruses can elicit DNA damage responses (DDRs) in host cells. In some cases the DDR presents a block to viral replication that must be overcome, and in other cases the infecting agent exploits the DDR to facilitate replication. We fi
Externí odkaz:
https://doaj.org/article/6bf81769819e4433a09e7f932d152cd7
Autor:
Iñigo Narvaiza, Daniel C Linfesty, Benjamin N Greener, Yoshiyuki Hakata, David J Pintel, Eric Logue, Nathaniel R Landau, Matthew D Weitzman
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000439 (2009)
The APOBEC3 proteins form a multigene family of cytidine deaminases with inhibitory activity against viruses and retrotransposons. In contrast to APOBEC3G (A3G), APOBEC3A (A3A) has no effect on lentiviruses but dramatically inhibits replication of th
Externí odkaz:
https://doaj.org/article/c9be6e30441e4dc4b3b23d56c804e04b
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1257 (2007)
Recombination-like structures formed at origins of DNA replication may contribute to replication fidelity, sister chromatid cohesion, chromosome segregation, and overall genome stability. The Epstein-Barr Virus (EBV) origin of plasmid replication (Or
Externí odkaz:
https://doaj.org/article/6d714780ada142b291cc198a4657ef68
Publikováno v:
Viruses, Vol 16, Iss 6, p 845 (2024)
Viruses exploit the host cell machinery to enable infection and propagation. This review discusses the complex landscape of DNA virus–host interactions, focusing primarily on herpesviruses and adenoviruses, which replicate in the nucleus of infecte
Externí odkaz:
https://doaj.org/article/d9708d2488724d13b7605eebc2b61af6
Autor:
Joseph M. Dybas, Krystal K. Lum, Katarzyna Kulej, Emigdio D. Reyes, Richard Lauman, Matthew Charman, Caitlin E. Purman, Robert T. Steinbock, Nicholas Grams, Alexander M. Price, Lydia Mendoza, Benjamin A. Garcia, Matthew D. Weitzman
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. Adenovirus (AdV) encodes pro
Externí odkaz:
https://doaj.org/article/8263a46ee7ba41df86e9a00e6d03a9fc