Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Matthew D, Woolard"'
Autor:
Gopi K. Kolluru, John D. Glawe, Sibile Pardue, Ahmad Kasabali, Shafiul Alam, Saranya Rajendran, Allison L. Cannon, Chowdhury S. Abdullah, James G. Traylor, Rodney E. Shackelford, Matthew D. Woolard, A. Wayne Orr, Nicholas E. Goeders, Paari Dominic, Md Shenuarin S. Bhuiyan, Christopher G. Kevil
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102480- (2022)
Methamphetamine (METH) is an addictive illicit drug used worldwide that causes significant damage to blood vessels resulting in cardiovascular dysfunction. Recent studies highlight increased prevalence of cardiovascular disease (CVD) and associated c
Externí odkaz:
https://doaj.org/article/6a7720c32f1b44d7a43b3cdd8db5312a
Autor:
Kasopefoluwa Y. Oguntuyo, Christian S. Stevens, Chuan Tien Hung, Satoshi Ikegame, Joshua A. Acklin, Shreyas S. Kowdle, Jillian C. Carmichael, Hsin-Ping Chiu, Kristopher D. Azarm, Griffin D. Haas, Fatima Amanat, Jéromine Klingler, Ian Baine, Suzanne Arinsburg, Juan C. Bandres, Mohammed N. A. Siddiquey, Robert M. Schilke, Matthew D. Woolard, Hongbo Zhang, Andrew J. Duty, Thomas A. Kraus, Thomas M. Moran, Domenico Tortorella, Jean K. Lim, Andrea V. Gamarnik, Catarina E. Hioe, Susan Zolla-Pazner, Stanimir S. Ivanov, Jeremy P. Kamil, Florian Krammer, Benhur Lee
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Vaccines and antibody-based therapeutics like convalescent-phase plasma therapy are premised upon inducing or transferring neutralizing antibodies that inhibit SARS-CoV-2 entry into cells. Virus neutralization assays (VNAs) for measuring neutralizing
Externí odkaz:
https://doaj.org/article/9f425d57749f4d2aabcd8c8d41ea0f24
Autor:
Sunitha Chandran, Robert M. Schilke, Cassidy M. R. Blackburn, Aila Yurochko, Rusella Mirza, Rona S. Scott, Brian N. Finck, Matthew D. Woolard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophage responses contribute to a diverse array of pathologies ranging from infectious disease to sterile inflammation. Polarization of macrophages determines their cellular function within biological processes. Lipin-1 is a phosphatidic acid phos
Externí odkaz:
https://doaj.org/article/2f929f1134fb4913933bcb98fe4f56da
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1449 (2020)
Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane fl
Externí odkaz:
https://doaj.org/article/fc85c8caa60e4845bbc27b606b4b562c
Autor:
Md. Shenuarin Bhuiyan, A. Wayne Orr, Xiuping Yu, Nicholas E. Goeders, Judy A. King, James G. Traylor, Paari Dominic, Brandon Hartman, Karen Y. Stokes, Connie L. Arnold, Sadia Nitu, Richa Aishwarya, Mohammad Alfrad Nobel Bhuiyan, Shafiul Alam, Mahboob Morshed, Manikandan Panchatcharam, Gopi K. Kolluru, Christopher G. Kevil, Sunitha Chandran, Matthew D. Woolard, Sumitra Miriyala, Chowdhury S. Abdullah, Naznin Sultana Remex
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-20 (2020)
Communications Biology
Communications Biology
Methamphetamine-associated cardiomyopathy is the leading cause of death linked with illicit drug use. Here we show that Sigmar1 is a therapeutic target for methamphetamine-associated cardiomyopathy and defined the molecular mechanisms using autopsy s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e86cf008e3435e72d7cae50deebf1b0
http://link.springer.com/article/10.1038/s42003-020-01408-z
http://link.springer.com/article/10.1038/s42003-020-01408-z
Autor:
David M. Krzywanski, Shashanka Rao, Matthew D. Woolard, Brian N. Finck, Cassidy M.R. Blackburn, Robert M. Schilke
Publikováno v:
ImmunoHorizons
Macrophages reprogram their metabolism to promote appropriate responses. Proresolving macrophages primarily use fatty acid oxidation as an energy source. Metabolites generated during the catabolism of fatty acids aid in the resolution of inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041834b53898fd6de205fceb2d32c409
http://europepmc.org/articles/PMC7739271
http://europepmc.org/articles/PMC7739271
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Heart disease is the leading cause of death in the United States and atherosclerosis accounts for nearly 75% of all deaths from heart disease. Atherosclerosis is a chronic inflammatory disease and mitochondrial reactive oxygen species (mtROS) are cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34c9d429158e7b92c79b1d2b26637a90
https://doi.org/10.1161/atvb.41.suppl_1.p157
https://doi.org/10.1161/atvb.41.suppl_1.p157
Autor:
Gopi Krishna K Kolluru, John D Glawe, Sibile Pardue, Ahmad Kasabali, Saranya RAJENDRAN, Allison L Cannon, Chowdhury S Abdullah, James G Traylor, Rodney Shackelford, Matthew D Woolard, Paari Dominic, Shenuarin Bhuiyan, Wayne W Orr, Nicholas E Goeders, Chris Kevil
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Background: Methamphetamine (METH) is an addictive illicit drug used worldwide that can elicit significant damage on blood vessels resulting in increased inflammation and cardiovascular dysfunction. Recent studies highlight increased prevalence of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33a970841efe83b6e1b225057d25bed
https://doi.org/10.1161/atvb.41.suppl_1.118
https://doi.org/10.1161/atvb.41.suppl_1.118
Autor:
Paari Dominic, Matthew D. Woolard, A. Wayne Orr, Connie L. Arnold, Md. Shenuarin Bhuiyan, Nicholas E. Goeders, Gopi K. Kolluru, Christopher G. Kevil, James G. Traylor
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:1739-1746
While the opioid epidemic has garnered significant attention, the use of methamphetamines is growing worldwide independent of wealth or region. Following overdose and accidents, the leading cause of death in methamphetamine users is cardiovascular di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ce3d39bc9ddb42dc88a269d3ff214a
https://doi.org/10.1161/atvbaha.119.312461
https://doi.org/10.1161/atvbaha.119.312461
Publikováno v:
The Journal of Immunology. 208:111.06-111.06
Free fatty acid accumulation in macrophages alters cellular metabolism, leading to failed inflammation resolution that contributes to cardiometabolic pathologies such as atherosclerotic cardiovascular disease. Free fatty acids are either broken down
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697e90cc7934457f896521b62c2cfe5b
https://doi.org/10.4049/jimmunol.208.supp.111.06
https://doi.org/10.4049/jimmunol.208.supp.111.06