Výsledky vyhledávání - "Matthew Coutsos"

Ventricular contraction and relaxation rates during muscle metaboreflex activation in heart failure: are they coupled?

Autor: Joseph Mannozzi, Donal S. O'Leary, Jasdeep Kaur, Louis Massoud, Matthew Coutsos

Publikováno v: Exp Physiol

NEW FINDINGS What is the central question of this study? Does the muscle metaboreflex affect the ratio of left ventricular contraction/relaxation rates and does heart failure impact this relationship. What is the main finding and its importance? The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50e38a735716f3427335fdc74ef6bf6
https://pubmed.ncbi.nlm.nih.gov/33226720

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Role of cardiac output versus peripheral vasoconstriction in mediating muscle metaboreflex pressor responses: dynamic exercise versus postexercise muscle ischemia

Autor: Matthew Coutsos, Donal S. O'Leary, Jasdeep Kaur, Robert A. Augustyniak, Marty D. Spranger, Javier A. Sala-Mercado, Doug Stayer

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 304:R657-R663

Muscle metaboreflex activation (MMA) during submaximal dynamic exercise in normal individuals increases mean arterial pressure (MAP) via increases in cardiac output (CO) with little peripheral vasoconstriction. The rise in CO occurs primarily via inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208c0f93a0b237c4dc4d846c2d754c67
https://doi.org/10.1152/ajpregu.00601.2012

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Muscle metaboreflex-induced coronary vasoconstriction limits ventricular contractility during dynamic exercise in heart failure

Autor: Masashi Ichinose, ZhenHua Li, Javier A. Sala-Mercado, Donal S. O'Leary, Elizabeth J. Dawe, Matthew Coutsos

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 304:H1029-H1037

Muscle metaboreflex activation (MMA) during dynamic exercise increases cardiac work and myocardial O2 demand via increases in heart rate, ventricular contractility, and afterload. This increase in cardiac work should lead to metabolic coronary vasodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a339b2ffc8340c5f47f590c765628d52
https://doi.org/10.1152/ajpheart.00879.2012

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Progressive muscle metaboreflex activation gradually decreases spontaneous heart rate baroreflex sensitivity during dynamic exercise

Autor: ZhenHua Li, Javier A. Sala-Mercado, Tomoko Ichinose, Masashi Ichinose, Dominic Fano, Donal S. O'Leary, Elizabeth J. Dawe, Matthew Coutsos

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 298:H594-H600

Ischemia of active skeletal muscle elicits a pressor response termed the muscle metaboreflex. We tested the hypothesis that in normal dogs during dynamic exercise, graded muscle metaboreflex activation (MMA) would progressively attenuate spontaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe25ad4dabf5dd1711abfd3464985b2
https://doi.org/10.1152/ajpheart.00908.2009

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Spontaneous baroreflex control of cardiac output during dynamic exercise, muscle metaboreflex activation, and heart failure

Autor: Marco Pallante, Matthew Coutsos, Robert L. Hammond, Masashi Ichinose, Javier A. Sala-Mercado, Tomoko Ichinose, Donal S. O'Leary, Ferdinando Iellamo

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 294:H1310-H1316

We have previously shown that spontaneous baroreflex-induced changes in heart rate (HR) do not always translate into changes in cardiac output (CO) at rest. We have also shown that heart failure (HF) decreases this linkage between changes in HR and C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7cc48af327b8935cd551cb35011b19
https://doi.org/10.1152/ajpheart.01187.2007

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Spontaneous baroreflex control of heart rate versus cardiac output: altered coupling in heart failure

Autor: Javier A. Sala-Mercado, Marco Pallante, Donal S. O'Leary, Robert L. Hammond, Ferdinando Iellamo, Tomoko Ichinose, Masashi Ichinose, Matthew Coutsos

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 294:H1304-H1309

Dynamic cardiac baroreflex responses are frequently investigated by analyzing the spontaneous reciprocal changes in arterial pressure and heart rate (HR). However, whether the spontaneous baroreflex-induced changes in HR translate into changes in car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df256a4f4d2c59b2b126cc71524447c1
https://doi.org/10.1152/ajpheart.01186.2007

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Attenuated muscle metaboreflex-induced increases in cardiac function in hypertension

Autor: Marty D. Spranger, Donal S. O'Leary, Matthew Coutsos, Rania Abu-Hamdah, Robert A. Augustyniak, Douglas Stayer, Javier A. Sala-Mercado, Jasdeep Kaur

Publikováno v: American journal of physiology. Heart and circulatory physiology. 305(10)

Sympathoactivation may be excessive during exercise in subjects with hypertension, leading to increased susceptibility to adverse cardiovascular events, including arrhythmias, infarction, stroke, and sudden cardiac death. The muscle metaboreflex is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471fa3e1a362d6e1a008f91bc2027e6f
https://pubmed.ncbi.nlm.nih.gov/24014673

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Dynamic cardiac output regulation at rest, during exercise, and muscle metaboreflex activation: impact of congestive heart failure

Autor: Elizabeth J. Dawe, Javier A. Sala-Mercado, Donal S. O'Leary, Matthew Coutsos, ZhenHua Li, Dominic Fano, Masashi Ichinose, Tomoko Ichinose

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology. 303(7)

We tested whether mild and moderate dynamic exercise and muscle metaboreflex activation (MMA) affect dynamic baroreflex control of heart rate (HR) and cardiac output (CO), and the influence of stroke volume (SV) fluctuations on CO regulation in norma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffb085bda63ab10ae1024c91c37ce7f
https://pubmed.ncbi.nlm.nih.gov/22855278

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