Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Matthew Coussens"'
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1571 (2008)
In mammals, Sirt1, a member of the sirtuin family of proteins, functions as a nicotinamide adenine dinucleotide-dependent protein deactylase, and has important physiological roles, including the regulation of glucose metabolism, cell survival, and mi
Externí odkaz:
https://doaj.org/article/9dddb427c61e4c248c79845b139888e1
Autor:
Minggui Pan, Adam M. Casey, Li Ding, Hong Zhang, Matthew Coussens, John D. Pfeifer, Edward Poyo, Yinqiu Wang, Carlton M. Bates, Piyush Tripathi, Nisha Basappa, Kalyan Reddy Manda, Feng Chen, Liang Ma, Congxing Lin
Publikováno v:
Oncogene. 33:1840-1849
NFAT (the nuclear factor of activated T cells) upregulation has been linked to cellular transformation intrinsically, but it is unclear whether and how tissue cells with NFAT activation change the local environment for tumor initiation and progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784c9efa367a6826120ee38abc31dcc0
https://doi.org/10.1038/onc.2013.132
https://doi.org/10.1038/onc.2013.132
Autor:
William H. Andrews, Christopher A. Foster, Richard C. Allsopp, Matthew Coussens, Lancer K. Brown, Philip Davy, Melissa Nagata
Publikováno v:
Proceedings of the National Academy of Sciences. 107:13842-13847
In various types of stem cells, including embryonic stem (ES) cells and hematopoietic stem cells, telomerase functions to ensure long-term self-renewal capacity via maintenance of telomere reserve. Expression of the catalytic component of telomerase,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ced7c64d30dbf1c3bdb6e638eae72df
https://doi.org/10.1073/pnas.0913834107
https://doi.org/10.1073/pnas.0913834107
Autor:
Prerna Prasad, Matthew Coussens, Guanglei Zhang, Trystan B. Wells, Irving L. Weissman, Richard C. Allsopp, Derrick J. Rossi, Homayoun Vaziri, Swami R. Narala
Publikováno v:
Molecular Biology of the Cell. 19:1210-1219
SIRT1, the mammalian homolog of SIR2 in Saccharomyces cerevisiae, is an NAD-dependent deacetylase implicated in regulation of lifespan. By designing effective short hairpin RNAs and a silent shRNA-resistant mutant SIRT1 in a genetically defined syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee4d64a640eba82426c816241a7b0c0
https://doi.org/10.1091/mbc.e07-09-0965
https://doi.org/10.1091/mbc.e07-09-0965
Autor:
Yukiko Yamazaki, Stefan Moisyadi, Ryuzo Yanagimachi, Matthew Coussens, Ryota Suganuma, Richard C. Allsopp
Publikováno v:
Biology of Reproduction. 75:785-791
Telomere length maintenance in the germ line from generation to generation is essential for the perpetuation of eukaryotic organisms. This task is performed by a specialized reverse transcriptase called telomerase. While this critical function of tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7538ebff73fbe68404ebf590d8ab6595
https://doi.org/10.1095/biolreprod.106.052167
https://doi.org/10.1095/biolreprod.106.052167
Tbx18 is a T-Box transcription factor that has specific expression and indispensible function in the lower urinary tract (Airik et al., 2006). Here, we report the generation and characterization of a bacterial artificial chromosome (BAC) transgene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b9e093c65821ee163b3b3efeadb12d
https://europepmc.org/articles/PMC2848076/
https://europepmc.org/articles/PMC2848076/
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1571 (2008)
PLoS ONE
PLoS ONE
In mammals, Sirt1, a member of the sirtuin family of proteins, functions as a nicotinamide adenine dinucleotide-dependent protein deactylase, and has important physiological roles, including the regulation of glucose metabolism, cell survival, and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998c7f03ac050d83598d9cf4c6aa8cb0
http://europepmc.org/articles/PMC2216432?pdf=render
http://europepmc.org/articles/PMC2216432?pdf=render
Autor:
Matthew, Coussens, Yukiko, Yamazaki, Stefan, Moisyadi, Ryota, Suganuma, Ryuzo, Yanagimachi, Richard, Allsopp
Publikováno v:
Biology of reproduction. 75(5)
Telomere length maintenance in the germ line from generation to generation is essential for the perpetuation of eukaryotic organisms. This task is performed by a specialized reverse transcriptase called telomerase. While this critical function of tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65846d8aa4bea6f2c11919a306d38ba1
https://pubmed.ncbi.nlm.nih.gov/16899651
https://pubmed.ncbi.nlm.nih.gov/16899651
Autor:
Matthew Coussens, Yinqiu Wang, Mario R. Capecchi, Michael R. Kuehn, Piyush Tripathi, Qiusha Guo, Helen Liapis, Sanjay Jain, Feng Chen
Publikováno v:
Developmental Biology. (2):518-527
The role of axial structures, especially the notochord, in metanephric kidney development has not been directly examined. Here, we showed that disruption of the notochord and floor plate by diphtheria toxin (DTA)-mediated cell ablation did not disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7934a8a348d2d423435e90e5e292c7