Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Matthew Catley"'
Autor:
Arjun K Ravi, Jonathan Plumb, Rosemary Gaskell, Sarah Mason, Caroline S Broome, George Booth, Matthew Catley, Jørgen Vestbo, Dave Singh
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Increased lung macrophage numbers in COPD may arise from upregulation of blood monocyte recruitment into the lungs. CCR5 is a monocyte chemokine receptor regulated by interleukin-6 (IL-6); the concentration of CCR5 ligands are kno
Externí odkaz:
https://doaj.org/article/61a222d4ffaa4dd494c89a0113503076
Autor:
Chia-Hao Lin, Cheng-Jang Wu, Sunglim Cho, Rasika Patkar, Ling-Li Lin, Mei-Chi Chen, Elisabeth Israelsson, Joanne Betts, Magdalena Niedzielska, Shefali A. Patel, Han G. Duong, Romana R. Gerner, Chia-Yun Hsu, Matthew Catley, Rose A. Maciewicz, Hiutung Chu, Manuela Raffatellu, John T. Chang, Li-Fan Lu
Publikováno v:
bioRxiv
Regulatory T (Treg) cells are instrumental in establishing immunological tolerance. However, the precise effector mechanisms by which Treg cells control a specific type of immune response in a given tissue remains unresolved. By simultaneously studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191745d22cd68b14fbab9a868827295a
https://doi.org/10.1101/2023.02.20.529261
https://doi.org/10.1101/2023.02.20.529261
Autor:
Pinelopi Andrikakou, Vikash Reebye, Daniel Vasconcelos, Sorah Yoon, Jon Voutila, Andrew J.T. George, Piotr Swiderski, Robert Habib, Matthew Catley, David Blakey, Nagy A. Habib, John J. Rossi, Kai-Wen Huang
Publikováno v:
Nucleic acid therapeutics. 32(6)
Metabolic syndrome (MetS) is a pathological condition characterized by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. Sirtuin 1 (SIRT1), a highly conserved histone deacetylase, is characterized as a key metabolic regulator a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9d81fa5f1efacf19ca5171f7835773
https://pubmed.ncbi.nlm.nih.gov/35895511
https://pubmed.ncbi.nlm.nih.gov/35895511
Publikováno v:
Mol Ther
Targeted delivery of oligonucleotides to liver hepatocytes using N-acetylgalactosamine (GalNAc) conjugates that bind to the asialoglycoprotein receptor has become a breakthrough approach in the therapeutic oligonucleotide field. This technology has l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30220b45b33db90153e4e962193eafe4
https://doi.org/10.1016/j.ymthe.2020.06.015
https://doi.org/10.1016/j.ymthe.2020.06.015
Autor:
Albert Kwok, Matthew Catley, David C. Blakey, Siv Anita Hegre, Laura Sinigaglia, Choon Ping Tan, Alexandre J. Debacker, Nagy A. Habib, Pål Sætrom
Publikováno v:
Cancer Immunology Research. 8:A72-A72
Small activating RNAs (saRNAs) are short, double-stranded oligonucleotides designed to specifically upregulate target mRNA and protein expression by loading into an Ago2 complex for nuclear translocation and activation of RNA polymerase II activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40eda35335841866bb5a713b0801993
https://doi.org/10.1158/2326-6074.tumimm19-a72
https://doi.org/10.1158/2326-6074.tumimm19-a72
Publikováno v:
Journal of Biological Chemistry. 274:19965-19972
The IκB kinases (IKKs) lie downstream of the NF-κB-inducing kinase (NIK) and activate NF-κB by phosphorylation of IκBα. This leads to IκBα degradation and release of NF-κB. In U937 monocytic cells, interleukin (IL)-1β (1 ng/ml) and tumor nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fc818868a52ab04bdf38d2c081d4bf
https://doi.org/10.1074/jbc.274.28.19965
https://doi.org/10.1074/jbc.274.28.19965