Výsledky vyhledávání - "Matthew C. Siracusa"

Akademický článek

Hybridization capture reveals evolution and conservation across the entire Koala retrovirus genome.

Autor: Kyriakos Tsangaras, Matthew C Siracusa, Nikolas Nikolaidis, Yasuko Ishida, Pin Cui, Hanna Vielgrader, Kristofer M Helgen, Alfred L Roca, Alex D Greenwood

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95633 (2014)

The koala retrovirus (KoRV) is the only retrovirus known to be in the midst of invading the germ line of its host species. Hybridization capture and next generation sequencing were used on modern and museum DNA samples of koala (Phascolarctos cinereu

Externí odkaz: https://doaj.org/article/0593e9fb19f94491b1638ac15838da1d

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Naturally Occurring Single Nucleotide Mutations Alter the Function of a Highly Conserved Hsp70 Gene in Humans

Autor: Nikolas Nikolaidis, Matthew C. Siracusa, Kyle Hess

Publikováno v: The FASEB Journal. 29

Molecular chaperones and in particular the 70-kD heat shock proteins (Hsp70s) are key regulators of the cellular stress response and alterations in their function have direct physiological conseque...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60649547c8f0b5c3e3d79b9214aa8eff
https://doi.org/10.1096/fasebj.29.1_supplement.713.3

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Functional Diversification and Specialization of Cytosolic 70-kDa Heat Shock Proteins

Autor: Nikolas Nikolaidis, Dimitra Chalkia, Chelsea McCallister, Matthew C. Siracusa, Farzaneh Shirazi

Publikováno v: Scientific Reports

A fundamental question in molecular evolution is how protein functional differentiation alters the ability of cells and organisms to cope with stress and survive. To answer this question we used two paralogous Hsp70s from mouse and explored whether t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3290cfc1ed3d1572090207a763bf708e
http://europepmc.org/articles/PMC4366816

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