Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Matthew C. Radey"'
Autor:
Hillary S. Hayden, Snehal Joshi, Matthew C. Radey, Anh T. Vo, Cara Forsberg, Sarah J. Morgan, Adam Waalkes, Elizabeth A. Holmes, Sara M. Klee, Mary J. Emond, Pradeep K. Singh, Stephen J. Salipante
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Within-host evolution produces genetic diversity in bacterial strains that cause chronic human infections. However, the lack of facile methods to measure bacterial allelic variation in clinical samples has limited understanding of intrastrai
Externí odkaz:
https://doaj.org/article/4b7a1eb8979d44feb0b346e6de35d676
Autor:
Sarah J. Morgan, Samantha L. Durfey, Sumedha Ravishankar, Peter Jorth, Wendy Ni, Duncan T. Skerrett, Moira L. Aitken, Edward F. McKone, Stephen J. Salipante, Matthew C. Radey, Pradeep K. Singh
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
A hallmark of chronic bacterial infections is the long-term persistence of 1 or more pathogen species at the compromised site. Repeated detection of the same bacterial species can suggest that a single strain or lineage is continually present. Howeve
Externí odkaz:
https://doaj.org/article/ae2c4456054541f9aec0c4f9751bc98b
Autor:
Samantha L. Durfey, Sudhakar Pipavath, Anna Li, Anh T. Vo, Anina Ratjen, Suzanne Carter, Sarah J. Morgan, Matthew C. Radey, Brenda Grogan, Stephen J. Salipante, Michael J. Welsh, David A. Stoltz, Christopher H. Goss, Edward F. McKone, Pradeep K. Singh
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Drugs called CFTR modulators improve the physiologic defect underlying cystic fibrosis (CF) and alleviate many disease manifestations. However, studies to date indicate that chronic lung infections that are responsible for most disease-relat
Externí odkaz:
https://doaj.org/article/6014c178cf2145dba42af057cdbac508
Autor:
Maria T. Nelson, Christopher E. Pope, Robyn L. Marsh, Daniel J. Wolter, Eli J. Weiss, Kyle R. Hager, Anh T. Vo, Mitchell J. Brittnacher, Matthew C. Radey, Hillary S. Hayden, Alexander Eng, Samuel I. Miller, Elhanan Borenstein, Lucas R. Hoffman
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2227-2240.e5 (2019)
Summary: Metagenomic sequencing is a promising approach for identifying and characterizing organisms and their functional characteristics in complex, polymicrobial infections, such as airway infections in people with cystic fibrosis. These analyses a
Externí odkaz:
https://doaj.org/article/aa353231eef24d6ba4bb9100acd19923
Autor:
Catherine R. Armbruster, Daniel J. Wolter, Meenu Mishra, Hillary S. Hayden, Matthew C. Radey, Gennifer Merrihew, Michael J. MacCoss, Jane Burns, Daniel J. Wozniak, Matthew R. Parsek, Lucas R. Hoffman
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT While considerable research has focused on the properties of individual bacteria, relatively little is known about how microbial interspecies interactions alter bacterial behaviors and pathogenesis. Staphylococcus aureus frequently coinfects
Externí odkaz:
https://doaj.org/article/cf5f148f17ca47f3bc5b80d2746e50f9
Autor:
Hillary S. Hayden, Susana Matamouros, Kyle R. Hager, Mitchell J. Brittnacher, Laurence Rohmer, Matthew C. Radey, Eli J. Weiss, Katie B. Kim, Michael A. Jacobs, Elizabeth H. Sims-Day, Min Yue, Mussaret B. Zaidi, Dieter M. Schifferli, Shannon D. Manning, Judd L. Walson, Samuel I. Miller
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Salmonella enterica serovar Typhimurium is one of the most common S. enterica serovars associated with U.S. foodborne outbreaks. S. Typhimurium bacteria isolated from humans exhibit wide-ranging virulence phenotypes in inbred mice, leading t
Externí odkaz:
https://doaj.org/article/db54af932ed441378875a50e1fe8f57f
Autor:
See-Yeun Ting, Kaitlyn D LaCourse, Hannah E Ledvina, Rutan Zhang, Matthew C Radey, Hemantha D Kulasekara, Rahul Somavanshi, Savannah K Bertolli, Larry A Gallagher, Jennifer Kim, Kelsi M Penewit, Stephen J Salipante, Libin Xu, S Brook Peterson, Joseph D Mougous
Publikováno v:
eLife, Vol 11 (2022)
Bacterial survival is fraught with antagonism, including that deriving from viruses and competing bacterial cells. It is now appreciated that bacteria mount complex antiviral responses; however, whether a coordinated defense against bacterial threats
Externí odkaz:
https://doaj.org/article/0ab2d6c17e7342c19c9b627071083d76
Autor:
Marcos H de Moraes, FoSheng Hsu, Dean Huang, Dustin E Bosch, Jun Zeng, Matthew C Radey, Noah Simon, Hannah E Ledvina, Jacob P Frick, Paul A Wiggins, S Brook Peterson, Joseph D Mougous
Publikováno v:
eLife, Vol 10 (2021)
When bacterial cells come in contact, antagonism mediated by the delivery of toxins frequently ensues. The potential for such encounters to have long-term beneficial consequences in recipient cells has not been investigated. Here, we examined the eff
Externí odkaz:
https://doaj.org/article/be2fdb917a1d4d3f92780957dc64d1bf
Autor:
Yaxi Wang, Larry A. Gallagher, Pia A. Andrade, Andi Liu, Ian R. Humphreys, Serdar Turkarslan, Kevin J. Cutler, Mario L. Arrieta-Ortiz, Yaqiao Li, Matthew C. Radey, Jeffrey S. McLean, Qian Cong, David Baker, Nitin S. Baliga, S. Brook Peterson, Joseph D. Mougous
Publikováno v:
bioRxiv
SummaryThe study of bacteria has yielded fundamental insights into cellular biology and physiology, biotechnological advances and many therapeutics. Yet due to a lack of suitable tools, the significant portion of bacterial diversity held within the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d6e7312aea8d749de677ada37fee94
https://europepmc.org/articles/PMC10187176/
https://europepmc.org/articles/PMC10187176/
Autor:
Yaxi Wang, Hannah E. Ledvina, Catherine A. Tower, Stanimir Kambarev, Elizabeth Liu, James C. Charity, Lieselotte S.M. Kreuk, Qiwen Chen, Larry A. Gallagher, Matthew C. Radey, Guilhem F. Rerolle, Yaqiao Li, Kelsi M. Penewit, Serdar Turkarslan, Shawn J. Skerrett, Stephen J. Salipante, Nitin S. Baliga, Joshua J. Woodward, Simon L. Dove, S. Brook Peterson, Jean Celli, Joseph D. Mougous
Glutathione (GSH) is an abundant metabolite that can act as a signal, a nutrient source, or serve in a redox capacity for intracellular pathogens. For Francisella, GSH is thought to be a critical in vivo source of cysteine; however, the cellular path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122a832db15a611c18edbe66c6192ce2
https://doi.org/10.1101/2023.02.02.526638
https://doi.org/10.1101/2023.02.02.526638