Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Matthew C. L. Phillips"'
Autor:
Matthew C. L. Phillips, Martin Picard
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract Neurodegenerative disorders are typically “split” based on their hallmark clinical, anatomical, and pathological features, but they can also be “lumped” by a shared feature of impaired mitochondrial biology. This leads us to present
Externí odkaz:
https://doaj.org/article/975a5dad0c274bd5b2465f336718f6ca
Autor:
Matthew C. L. Phillips, Samuel E. Johnston, Pat Simpson, David K. Chang, Danielle Mather, Rognvald J. Dick
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder. The most devastating variant is bulbar-onset ALS, which portends a median survival of 24 months from the onset of symptoms. Abundant evidence indicates that neuron metabo
Externí odkaz:
https://doaj.org/article/4e88d55051f1487cae4431a13ca018ee
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Huntington's disease (HD) is a progressive, fatal neurodegenerative disorder with limited treatment options. Substantial evidence implicates mitochondria dysfunction in brain and skeletal muscle in the pathogenesis of HD. Metabolic strategies, such a
Externí odkaz:
https://doaj.org/article/97d7a5a1a952445db5db18a13c2529bb
Autor:
Matthew C. L. Phillips, Laura M. Deprez, Grace M. N. Mortimer, Deborah K. J. Murtagh, Stacey McCoy, Ruth Mylchreest, Linda J. Gilbertson, Karen M. Clark, Patricia V. Simpson, Eileen J. McManus, Jee-Eun Oh, Satish Yadavaraj, Vanessa M. King, Avinesh Pillai, Beatriz Romero-Ferrando, Martijn Brinkhuis, Bronwyn M. Copeland, Shah Samad, Shenyang Liao, Jan A. C. Schepel
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, da
Externí odkaz:
https://doaj.org/article/70dd2699502f44b381a8555e3317d0f2
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Sporadic inclusion body myositis (IBM) is a chronic inflammatory and degenerative muscle disease with limited treatment options; no therapy can alter its natural course. Ketogenic diets are theoretically capable of suppressing inflammation, enhancing
Externí odkaz:
https://doaj.org/article/a122e8297fed409da0ec5695bf65afd2
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Thymomas consist of neoplastic thymic cells intermixed with variable numbers of non-neoplastic lymphocytes. Metastatic thymomas are typically managed with non-curative chemotherapy to control tumor-related symptoms; no prolonged survival is expected.
Externí odkaz:
https://doaj.org/article/837614151ced4e7585bd5259efc46ccc
Autor:
Matthew C. L. Phillips, Antoaneta Balabanov, Clare Williams, Colin P. Doherty, Susan Wood, Cherubino Di Lorenzo, Janak K. Nathan, Jennifer Langer, Orrin Devinsky, Patty Nguyen, Kelly Roehl, Jude Munn, Adrianna Tanner, Mackenzie C. Cervenka, Magnhild Kverneland, Mesha-Gay Brown, Elizabeth A. Felton, Pavel Klein, Eduard Bercovici, Danielle A.J.E. Lambrechts, Laura A. Healy, Manny Bagary, Beth Zupec-Kania
Publikováno v:
Neurol Clin Pract
ObjectiveTo evaluate current clinical practices and evidence-based literature to establish preliminary recommendations for the management of adults using ketogenic diet therapies (KDTs).MethodsA 12-topic survey was distributed to international expert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a846a77f05275d2ba868d5266ceb6d
https://europepmc.org/articles/PMC8610544/
https://europepmc.org/articles/PMC8610544/
Publikováno v:
Poster abstracts.
Background Glioblastoma (GBM) is an aggressive form of glioma. Even with standard-of-care Stupp protocol (surgery, radiotherapy, and temozolomide), median overall survival is only 10-12 months in population-based studies. Metabolic reprogramming is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c542101da42cc139a795bef1b518dd38
https://doi.org/10.1136/bmjno-2021-anzan.44
https://doi.org/10.1136/bmjno-2021-anzan.44
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Frontiers in Neurology
Frontiers in Neurology
Sporadic inclusion body myositis (IBM) is a chronic inflammatory and degenerative muscle disease with limited treatment options; no therapy can alter its natural course. Ketogenic diets are theoretically capable of suppressing inflammation, enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793069b9ab9bfe4a970a9b20f90a4769
https://www.frontiersin.org/articles/10.3389/fneur.2020.582402/full
https://www.frontiersin.org/articles/10.3389/fneur.2020.582402/full
Autor:
Avinesh Pillai, Eileen J. McManus, Ruth Mylchreest, Jan Schepel, Patricia V. Simpson, Linda J. Gilbertson, Laura M. Deprez, Shenyang Liao, Beatriz Romero-Ferrando, Bronwyn Copeland, Stacey McCoy, Deborah K. J. Murtagh, Jee-Eun Oh, Grace M. N. Mortimer, Satish Yadavaraj, Vanessa M. King, Karen M. Clark, Matthew C. L. Phillips, Martijn Brinkhuis, Shah Samad
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, daily funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcaf26f034574573f5a9b3ee53e947a2
https://pubmed.ncbi.nlm.nih.gov/33622392
https://pubmed.ncbi.nlm.nih.gov/33622392