Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Matthew C. Havrda"'
Autor:
Faith L. Anderson, Katharine M. von Herrmann, Angeline S. Andrew, Yuliya I. Kuras, Alison L. Young, Clemens R. Scherzer, William F. Hickey, Stephen L. Lee, Matthew C. Havrda
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms and loss of dopaminergic neurons of the substantia nigra. Inflammation and cell death are recognized aspects of PD suggesting that strat
Externí odkaz:
https://doaj.org/article/892f9bbb0b7f49018d57cd57aa5de398
Autor:
Katharine M. von Herrmann, Faith L. Anderson, Eileen M. Martinez, Alison L. Young, Matthew C. Havrda
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background An association between neuroinflammation and age-related neurologic disorders has been established but the molecular mechanisms and cell types involved have not been thoroughly characterized. Activity of the proinflammatory NLRP3
Externí odkaz:
https://doaj.org/article/824e459d84c045ecaefd5f2514ed79a4
Autor:
Angeline S. Andrew, Faith L. Anderson, Stephen L. Lee, Katharine M. Von Herrmann, Matthew C. Havrda
Publikováno v:
Parkinson's Disease, Vol 2021 (2021)
Introduction. Parkinson’s disease (PD) is an age-related neurodegenerative disease likely caused by complex interactions between genetic and environmental risk factors. Exposure to pesticides, toxic metals, solvents, and history of traumatic brain
Externí odkaz:
https://doaj.org/article/cb381840d5da47b8b3cc023040f67cdf
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 819-827 (2013)
SUMMARY Characterizing dopaminergic neuronal development and function in novel genetic animal models might uncover strategies for researchers to develop disease-modifying treatments for neurologic disorders. Id2 is a transcription factor expressed in
Externí odkaz:
https://doaj.org/article/f32978a8759341948ac85b6b79deddfa
Publikováno v:
Translational Research. 252:21-33
Neurodegenerative diseases are characterized by a dysregulated neuro-glial microenvironment, culminating in functional deficits resulting from neuronal cell death. Inflammation is a hallmark of the neurodegenerative microenvironment and despite a cri
Autor:
Mark A. Israel, Matthew Ung, Chao Cheng, Zhonghua Zhang, Yasuyuki Hitoshi, Huan Liu, Matthew C. Havrda, Cong Ran, Damian A. Almiron Bonnin
PDGFR expression in recurring GFAP/tTA:TRE/hPDGFB allografts resistant to hPDGFB suppression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f723e14e884a32dc27f7d5f43106ee
https://doi.org/10.1158/1535-7163.22508590
https://doi.org/10.1158/1535-7163.22508590
Autor:
Mark A. Israel, Matthew Ung, Chao Cheng, Zhonghua Zhang, Yasuyuki Hitoshi, Huan Liu, Matthew C. Havrda, Cong Ran, Damian A. Almiron Bonnin
Forward and reverse primers sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db9f192b6597d89f20404fa05f7225e
https://doi.org/10.1158/1535-7163.22508581.v1
https://doi.org/10.1158/1535-7163.22508581.v1
Autor:
Mark A. Israel, Matthew Ung, Chao Cheng, Zhonghua Zhang, Yasuyuki Hitoshi, Huan Liu, Matthew C. Havrda, Cong Ran, Damian A. Almiron Bonnin
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce8f50e1af49b95c161c07aec04ecef
https://doi.org/10.1158/1535-7163.22508587
https://doi.org/10.1158/1535-7163.22508587
Publikováno v:
Toxicol Sci
Exposure to environmental toxicants can increase the risk of developing age-related neurodegenerative disorders. Exposure to the widely used organophosphate pesticide chlorpyrifos (CPF) is associated with increased risk of developing Alzheimer’s di
Autor:
Sumyuktha V. Anand, Min K. Lee, Alexander G. Skorput, Isabella B. Fox, Alison L. Young, Brock C. Christensen, Allan Gulledge, Matthew C. Havrda
Publikováno v:
Cancer Research. 83:5801-5801
Primary gliomas arising within the brain are the deadliest form of brain cancer and account for 78% of all malignant brain tumors. Glioma patients have a 5 percent five-year survival rate and drug-resistant tumors often recur following surgical resec