Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Matthew C Wollerton"'
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 11:291-303
This article describes a novel robotic system for protein expression and purification. This area has traditionally proved a bottleneck in pharmaceutical discovery owing to the difficulty and unpredictability of outcome in evaluating multiple sets of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd2a30a3cb7e0531c5cd4d4ee055837
https://doi.org/10.1016/j.jala.2006.08.002
https://doi.org/10.1016/j.jala.2006.08.002
Autor:
Nuno L. Barbosa-Morais, Vladimir Benes, Matthew C Wollerton, Maria Carmo-Fonseca, Juan Valcárcel, Christopher W.J. Smith, Anita Quintal Gomes, Teresa R. Pacheco, Wilhelm Ansorge
Publikováno v:
Journal of Biological Chemistry. 279:27039-27049
U2 small nuclear ribonucleoprotein auxiliary factor small subunit (U2AF(35)) is encoded by a conserved gene designated U2AF1. Here we provide evidence for the existence of alternative vertebrate transcripts encoding different U2AF(35) isoforms. Three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e3a193111a7a91a9e2a0bd828efe33
https://doi.org/10.1074/jbc.m402136200
https://doi.org/10.1074/jbc.m402136200
Autor:
Clare Gooding, Matthew C Wollerton, Eric J. Wagner, Christopher W.J. Smith, Mariano A. Garcia-Blanco
Publikováno v:
Molecular Cell. 13(1):91-100
Polypyrimdine tract binding protein (PTB) is a regulator of alternative splicing, mRNA 3' end formation, mRNA stability and localization, and IRES-mediated translation. Transient overexpression of PTB can influence alternative splicing, sometimes res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fa4e4c1675bd43b9054ace3fd8c8be
Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB)
Autor:
Matthew C Wollerton, Clare Gooding, Christopher W.J. Smith, Richard J. Jackson, Fiona Robinson, Emma C. Brown
Publikováno v:
RNA. 7:819-832
Polypyrimidine tract binding protein (PTB) is an RNA-binding protein that regulates splicing by repressing specific splicing events. It also has roles in 3'-end processing, internal initiation of translation, and RNA localization. PTB exists in three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124dacde09b8bd11b2c7f21ef9ee9d79
https://doi.org/10.1017/s1355838201010214
https://doi.org/10.1017/s1355838201010214
Autor:
Clare, Gooding, Francis, Clark, Matthew C, Wollerton, Sushma-Nagaraja, Grellscheid, Harriet, Groom, Christopher W J, Smith
Publikováno v:
Genome Biology
Exons with predicted branch points were identified from a large dataset of human exons and the importance of these branch points for splicing was verified.
Background The three consensus elements at the 3' end of human introns - the branch point
Background The three consensus elements at the 3' end of human introns - the branch point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b59818b00ee0130c7c3810f4d31278c5
https://pubmed.ncbi.nlm.nih.gov/16507133
https://pubmed.ncbi.nlm.nih.gov/16507133
Autor:
Alexis P Rideau, Justine Southby, Nicholas J. McGlincy, Fiona Robinson, Matthew C Wollerton, Arianne J. Matlin, Sushma Nagaraja Grellscheid, Clare Gooding, Christopher W.J. Smith, R. Spellman
Publikováno v:
Biochemical Society transactions. 33(Pt 3)
PTB (polypyrimidine tract-binding protein) is a repressive regulator of alternative splicing. We have investigated the role of PTB in three model alternative splicing systems. In the α-actinin gene, PTB represses the SM (smooth muscle) exon by bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399f88bf39a41bbab773aafc825dddc5
https://pubmed.ncbi.nlm.nih.gov/15916540
https://pubmed.ncbi.nlm.nih.gov/15916540
Autor:
Sushma Nagaraja Grellscheid, Matthew C Wollerton, Harriet C. T. Groom, Francis Clark, Clare Gooding, Christopher W.J. Smith
Publikováno v:
Genome Biology. 7:R1
The three consensus elements at the 3' end of human introns - the branch point sequence, the polypyrimidine tract, and the 3' splice site AG dinucleotide - are usually closely spaced within the final 40 nucleotides of the intron. However, the branch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b3872cca23c96a30953fe24af7565b
https://doi.org/10.1186/gb-2006-7-1-r1
https://doi.org/10.1186/gb-2006-7-1-r1
Autor:
Andre Furger, Matthew C Wollerton, Pedro Castelo-Branco, Chris Smith, Alexandra Moreira, Nick J. Proudfoot
Publikováno v:
Molecular and Cellular Biology. 24:6889-6889
Polypyrimidine tract binding protein (PTB) is a major hnRNP protein with multiple roles in mRNA metabolism, including regulation of alternative splicing and internal ribosome entry site-driven translation. We show here that a fourfold overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a732e1d2f8b1d9818f64876406f2e59
https://doi.org/10.1128/mcb.24.15.6889.2004
https://doi.org/10.1128/mcb.24.15.6889.2004