A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

Autor: Benjamin Cottam, Kristina Young, Pippa Newell, Todd Crocenzi, Chet Hammill, Zeljka Jutric, Ronald F. Wolf, Paul D. Hansen, Matthew C. Solhjem, Yue-Yun To, Amy Greathouse, Garth Tormoen, Keith S. Bahjat, Michael J. Gough, Marka R. Crittenden

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)

Background Preclinical studies have shown synergy between radiation therapy and immunotherapy. However, in almost all preclinical models, radiation is delivered in single doses or short courses of high doses (hypofractionated radiation). By contrast

Externí odkaz: https://doaj.org/article/2403eb5742d0484c8d84f42cda596a9b

A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

Autor: Matthew C. Solhjem, Pippa Newell, Ronald F. Wolf, Paul D. Hansen, Michael J. Gough, Kristina H. Young, Benjamin Cottam, Chet W. Hammill, Todd S. Crocenzi, Keith S. Bahjat, Zeljka Jutric, Marka R. Crittenden, Garth W. Tormoen, Amy Greathouse, Yue-Yun To

Publikováno v: Journal for Immunotherapy of Cancer
Crocenzi, T; Cottam, B; Newell, P; Wolf, RF; Hansen, PD; Hammill, C; et al.(2016). A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 4, 45. doi: 10.1186/s40425-016-0149-6. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4x4214z6

Background Preclinical studies have shown synergy between radiation therapy and immunotherapy. However, in almost all preclinical models, radiation is delivered in single doses or short courses of high doses (hypofractionated radiation). By contrast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f96babdfb5eaccd8d0973b3d0e517a5
https://pubmed.ncbi.nlm.nih.gov/27532020

Intensity-Modulated Radiotherapy for Head-and-Neck Cancer in the Community Setting

Autor: Eric Hansen, Jeannie Louie, Matthew C. Solhjem, Steven K. Seung, Christine Cha, Stephen B. Bader, K. Underhill, David E. Gannett, Joseph Bae

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 72:1075-1081

Purpose To review outcomes with intensity-modulated radiation therapy (IMRT) in the community setting for the treatment of nasopharyngeal and oropharyngeal cancer. Methods and Materials Between April 2003 and April 2007, 69 patients with histological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff6642b0c0dc509bd6b986091fd4264
https://doi.org/10.1016/j.ijrobp.2008.02.016

Prostate volume measurement by transrectal ultrasound and computed tomography before and after permanent prostate brachytherapy

Autor: Michael G. Herman, Thomas M. Pisansky, Lance A. Mynderse, Bernard F. King, Matthew C. Solhjem, Torrence M. Wilson, Susan Geyer, Brian J. Davis

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 60:767-776

To quantify prostate volume (pvol) changes with transrectal ultrasound (TRUS) immediately after permanent prostate brachytherapy (PPB) and to correlate these changes with postimplant computed tomography (CT) volumetrics. To provide data relevant to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cde3922aecabdc29854d1f4f71a752
https://doi.org/10.1016/j.ijrobp.2004.04.015

An exploratory phase I trial of immunochemoradiotherapy in locally advanced and borderline resectable (LA/BR) pancreatic adenocarcinoma (PC)

Autor: Steven K. Seung, Michael Owens, Ronald L. Wolf, Chet W. Hammill, Walter J. Urba, Anupama Kurup, Marka R. Crittenden, Lehel Somogyi, Michael J. Gough, James Regan, Todd S. Crocenzi, Matthew C. Solhjem, Carlo Bifulco, Michael Phillips, Shane Orion Rogosin, Pippa Newell, Alan Savoy, Xiaohong Cai, Alexandru Bageac

Publikováno v: Journal of Clinical Oncology. 31:174-174

174 Background: The primary aim of this exploratory trial was to determine the feasibility and safety of chemoradiotherapy (CRT) with combinatorial immunotherapy in LA or BR PC. Methods: 10 patients (pts) with untreated, LA (n=6) or BR (n=4) biopsy-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::682534e0bec747d9edb8786e62915daa
https://doi.org/10.1200/jco.2013.31.4_suppl.174