Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Matthew Ballew"'
Autor:
Xing Wang, Natasha Raman, Ghali Lemtiri-Chlieh, Jinhee Chang, Shreya Jagtap, Dipanwita Dutta Chowdhury, Matthew Ballew, Francesca Anna Carrieri, Triet Nguyen, Katriana Nugent, Travis Peck, Michelle S. Levine, Aaron Chan, Christine Lam, Reem Malek, Tung Hoang, Ryan Phillips, ZhuoAn Cheng, Kekoa Taparra, Nick Connis, Christine L. Hann, Andrew Holland, Phuoc T. Tran, Audrey Lafargue, Hailun Wang
Publikováno v:
Molecular Cancer Therapeutics. 22:519-528
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c109ad13608c562d8b330269ae2aa510
https://doi.org/10.1158/1535-7163.mct-22-0191
https://doi.org/10.1158/1535-7163.mct-22-0191
Autor:
Hailun Wang, Audrey Lafargue, Phuoc T. Tran, Andrew Holland, Christine L. Hann, Nick Connis, Kekoa Taparra, ZhuoAn Cheng, Ryan Phillips, Tung Hoang, Reem Malek, Christine Lam, Aaron Chan, Michelle S. Levine, Travis Peck, Katriana Nugent, Triet Nguyen, Francesca Anna Carrieri, Matthew Ballew, Dipanwita Dutta Chowdhury, Shreya Jagtap, Jinhee Chang, Ghali Lemtiri-Chlieh, Natasha Raman, Xing Wang
Figure S1 shows basal centrosome amplification in cell lines. Figure S2 shows the effect of GF on cell viability. Figure S3 shows HSET expression in cell lines. Figure S4 shows the effect of GF on clonogenic potential after RT. Figure S5 shows the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c532a3a2eded80823b7fec1b40a3091
https://doi.org/10.1158/1535-7163.22552221.v1
https://doi.org/10.1158/1535-7163.22552221.v1
Autor:
Hailun Wang, Audrey Lafargue, Phuoc T. Tran, Andrew Holland, Christine L. Hann, Nick Connis, Kekoa Taparra, ZhuoAn Cheng, Ryan Phillips, Tung Hoang, Reem Malek, Christine Lam, Aaron Chan, Michelle S. Levine, Travis Peck, Katriana Nugent, Triet Nguyen, Francesca Anna Carrieri, Matthew Ballew, Dipanwita Dutta Chowdhury, Shreya Jagtap, Jinhee Chang, Ghali Lemtiri-Chlieh, Natasha Raman, Xing Wang
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66f7a770018e1fbf7d210f058e865a5
https://doi.org/10.1158/1535-7163.c.6534769.v2
https://doi.org/10.1158/1535-7163.c.6534769.v2
Autor:
Hailun Wang, Audrey Lafargue, Phuoc T. Tran, Andrew Holland, Christine L. Hann, Nick Connis, Kekoa Taparra, ZhuoAn Cheng, Ryan Phillips, Tung Hoang, Reem Malek, Christine Lam, Aaron Chan, Michelle S. Levine, Travis Peck, Katriana Nugent, Triet Nguyen, Francesca Anna Carrieri, Matthew Ballew, Dipanwita Dutta Chowdhury, Shreya Jagtap, Jinhee Chang, Ghali Lemtiri-Chlieh, Natasha Raman, Xing Wang
Supplementary Materials & Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2d716a8a76c09055899f40d1e6a6d2
https://doi.org/10.1158/1535-7163.22495198.v1
https://doi.org/10.1158/1535-7163.22495198.v1
Autor:
Matthew Ballew, Saumendra N. Sarkar, Thomas P. Conrads, Greg M. Delgoffe, Mark J. O'Connor, Jan H. Beumer, R. Lalonde, David A. Clump, Brian F. Kiesel, Frank P. Vendetti, Pooja Karukonda, Troy P. Teo, Robert L. Ferris, Phuoc T. Tran, Katriana Nugent, Christopher J. Bakkenist
Publikováno v:
Journal of Clinical Investigation. 128:3926-3940
DNA-damaging chemotherapy and radiation therapy are integrated into the treatment paradigm of the majority of cancer patients. Recently, immunotherapy that targets the immunosuppressive interaction between programmed death 1 (PD-1) and its ligand PD-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6739ba9836b95688ea1d8605ea7be40b
https://doi.org/10.1172/jci96519
https://doi.org/10.1172/jci96519
Autor:
Hailun Wang, Dean W. Felsher, Natasha E. Zachara, Phuoc T. Tran, Kenneth J. Pienta, Katriana Nugent, Brian W. Simons, Jennifer Groves, Bin Zhang, Barry D. Nelkin, Xing Wang, Ken Wang, Gokben Yildirir, Audrey Lafargue, Mustafa A. Barbhuiya, Takumi Shiraishi, John Wong, Matthew Ballew, Kekoa Taparra, Reem Malek, James E. Verdone, Russell Williams, Roger Henry
Publikováno v:
Molecular Cancer Research. 18:B11-B11
Mutant KRAS drives glycolytic flux in lung cancer, potentially impacting aberrant protein glycosylation. Recent evidence suggests aberrant KRAS drives flux of glucose into the hexosamine biosynthetic pathway (HBP). HBP is required for various glycosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29541126da57b9337c783c330a6e5fca
https://doi.org/10.1158/1557-3125.ras18-b11
https://doi.org/10.1158/1557-3125.ras18-b11
Autor:
Sarah Manmiller, Kekoa Taparra, Jessica Cades, Reem Malek, Katriana Nugent, Yoshinori Kato, Zineb Belcaid, Sivarajan T. Chettiar, Hailun Wang, Michael Lim, David Proia, Anvesh Annadanam, Matthew Ballew, Robert A. Anders, Joseph M. Herman, Phuoc T. Tran
Publikováno v:
Cancer Biology & Therapy
Therapies for liver cancer particularly those including radiation are still inadequate. Inhibiting the stress response machinery is an appealing anti-cancer and radiosensitizing therapeutic strategy. Heat-shock-protein-90 (HSP90) is a molecular chape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a83db254c9001fe60b87b6fe510ada
http://europepmc.org/articles/PMC4910914
http://europepmc.org/articles/PMC4910914
Autor:
Natasha Raman, Andrew J. Holland, Phuoc T. Tran, Hailun Wang, Katriana Nugent, Michelle S. Levine, Ghali Lemtiri-Chlieh, Matthew Ballew
Publikováno v:
Clinical Cancer Research. 24:B12-B12
The centrosome is a microtubule-organizing center that plays an important role during M-phase and cell division where it organizes the two poles of the bipolar microtubule spindle apparatus from which chromosomes are segregated. In contrast to most n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2dc3790a8d6eb5067985e50dfb733f
https://doi.org/10.1158/1557-3265.aacriaslc18-b12
https://doi.org/10.1158/1557-3265.aacriaslc18-b12
Autor:
Katriana Nugent, James E. Verdone, Hailun Wang, Phuoc T. Tran, Mustafa A. Barbhuiya, Takumi Shiraishi, Bin Zhang, Russell Williams, Barry D. Nelkin, Natasha E. Zachara, Roger Henry, Kekoa Taparra, Reem Malek, Kenneth J. Pienta, Audrey Lafargue, Ken Kang Hsin Wang, John Wong, Matthew Ballew, Jennifer Groves, Gokben Yildirir, Dean W. Felsher, Brian W. Simons, Xing Wang
Publikováno v:
The Journal of clinical investigation. 128(11)
Mutant KRAS drives glycolytic flux in lung cancer, potentially impacting aberrant protein glycosylation. Recent evidence suggests aberrant KRAS drives flux of glucose into the hexosamine biosynthetic pathway (HBP). HBP is required for various glycosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75ca548e1cdb84e096fabe6c53b7881
https://pubmed.ncbi.nlm.nih.gov/30130254
https://pubmed.ncbi.nlm.nih.gov/30130254
Autor:
Michelle Vaz, Phuoc T. Tran, Noushin Niknafs, Jessica Hicks, Victor E. Velculescu, Alyssa Wenzel, Matthew Ballew, Reiner Strick, Cynthia A. Zahnow, Katherine B. Chiappinelli, Pamela L. Strissel, Ray Whay Chiu Yen, Stephen B. Baylin, Meredith L. Stone, Valsamo Anagnostou, Christina E. DeStefano Shields, Michael J. Topper, Matthew D. Hellmann
Publikováno v:
Cell. 171:1284-1300.e21
Combining DNA-demethylating agents (DNA methyltransferase inhibitors [DNMTis]) with histone deacetylase inhibitors (HDACis) holds promise for enhancing cancer immune therapy. Herein, pharmacologic and isoform specificity of HDACis are investigated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101b86a9a3301b8333abfc1d8f2f98ca
https://doi.org/10.1016/j.cell.2017.10.022
https://doi.org/10.1016/j.cell.2017.10.022