Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthew B. Taylor"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
Cryptic genetic variants may not individually show discernible phenotypic effects, but collectively, these polymorphisms can lead to unexpected, genetically complex traits that might be relevant to evolution and disease. Here, the authors use large y
Externí odkaz:
https://doaj.org/article/3a1bf6e4df6343bc91f360692be3d312
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005929 (2016)
Determining how genetic variation alters the expression of heritable phenotypes across conditions is important for agriculture, evolution, and medicine. Central to this problem is the concept of genotype-by-environment interaction (or 'GxE'), which o
Externí odkaz:
https://doaj.org/article/ce31950a0cd24dd6975a21002cf44510
Autor:
Matthew B Taylor, Ian M Ehrenreich
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005606 (2015)
Disruption of certain genes can reveal cryptic genetic variants that do not typically show phenotypic effects. Because this phenomenon, which is referred to as 'phenotypic capacitance', is a potential source of trait variation and disease risk, it is
Externí odkaz:
https://doaj.org/article/b4c9f4bbf26a4ceb8a02cdcfc20c51e3
Autor:
Matthew B Taylor, Ian M Ehrenreich
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004324 (2014)
Recent research suggests that genetic interactions involving more than two loci may influence a number of complex traits. How these 'higher-order' interactions arise at the genetic and molecular levels remains an open question. To provide insights in
Externí odkaz:
https://doaj.org/article/f6b12b62cfae42e8982c5e062e3042d3
Autor:
Students y, Maitreya J. Dunham, Josephine M. Boyer, Warwick Ar, Walson M, Angela Shang-Mei Hickey, Matthew B. Taylor, Paul A. Rowley, Skophammer R, Large Crl
Antifungal resistance in pathogenic fungi is a growing global health concern. Non-pathogenic laboratory strains of Saccharomyces cerevisiae are a useful model for studying mechanisms of antifungal resistance that are relevant to understanding the sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29cf9d15187cc4029c1663660a7f49cf
https://doi.org/10.1101/2021.05.02.442375
https://doi.org/10.1101/2021.05.02.442375
Autor:
Matthew B. Taylor, Ian M. Ehrenreich
Publikováno v:
Trends in Genetics. 31:34-40
The contribution of genetic interactions involving three or more loci to complex traits is poorly understood. Because these higher-order genetic interactions (HGIs) are difficult to detect in genetic mapping studies, very few examples of them have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2e2bdd379d3eec4d987c916c044733
https://doi.org/10.1016/j.tig.2014.09.001
https://doi.org/10.1016/j.tig.2014.09.001
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
Nature Communications
Nature Communications
Cryptic genetic variants that do not typically influence traits can interact epistatically with each other and mutations to cause unexpected phenotypes. To improve understanding of the genetic architectures and molecular mechanisms that underlie thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e2dee786ef3c52048989cfffdde618
https://doi.org/10.1038/ncomms11669
https://doi.org/10.1038/ncomms11669
Autor:
Ian M. Ehrenreich, Matthew B. Taylor
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 10, p e1005606 (2015)
PLoS Genetics, Vol 11, Iss 10, p e1005606 (2015)
Disruption of certain genes can reveal cryptic genetic variants that do not typically show phenotypic effects. Because this phenomenon, which is referred to as ‘phenotypic capacitance’, is a potential source of trait variation and disease risk, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecfa93920aab6d8841d3d106d2c48c0
https://pubmed.ncbi.nlm.nih.gov/26484664
https://pubmed.ncbi.nlm.nih.gov/26484664
Autor:
Ian M. Ehrenreich, Matthew B. Taylor
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 5, p e1004324 (2014)
PLoS Genetics, Vol 10, Iss 5, p e1004324 (2014)
Recent research suggests that genetic interactions involving more than two loci may influence a number of complex traits. How these ‘higher-order’ interactions arise at the genetic and molecular levels remains an open question. To provide insight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa4c1bbad436e350ec0694399e6c4ea
http://europepmc.org/articles/PMC4006734
http://europepmc.org/articles/PMC4006734
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005929 (2016)
PLoS Genetics, Vol 12, Iss 3, p e1005929 (2016)
Determining how genetic variation alters the expression of heritable phenotypes across conditions is important for agriculture, evolution, and medicine. Central to this problem is the concept of genotype-by-environment interaction (or ‘GxE’), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fbcea315e175e25aa4e2cd4fc268c8
https://doi.org/10.1371/journal.pgen.1005929
https://doi.org/10.1371/journal.pgen.1005929