Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Matthew B. Lawrenz"'
Autor:
Sarah L. Price, Robert S. Oakes, Rodrigo J. Gonzalez, Camilla Edwards, Amanda Brady, Jennifer K. DeMarco, Ulrich H. von Andrian, Christopher M. Jewell, Matthew B. Lawrenz
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108600- (2024)
Summary: Fleas transmit Yersinia pestis directly within the dermis of mammals to cause bubonic plague. Syringe-mediated inoculation is widely used to recapitulate bubonic plague and study Y. pestis pathogenesis. However, intradermal needle inoculatio
Externí odkaz:
https://doaj.org/article/8a28d90b249d4b2bbf3092468bce29cf
Autor:
Judith Behnsen, Hui Zhi, Allegra T. Aron, Vivekanandan Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B. Lawrenz, Robert D. Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, Manuela Raffatellu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and t
Externí odkaz:
https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf
Autor:
Jonathan M. Warawa, Xiaoxian Duan, Charles D. Anderson, Julie B. Sotsky, Daniel E. Cramer, Tia L. Pfeffer, Haixun Guo, Scott Adcock, Alexander J. Lepak, David R. Andes, Stacey A. Slone, Arnold J. Stromberg, Jon D. Gabbard, William E. Severson, Matthew B. Lawrenz
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT The rise in infections caused by antibiotic-resistant bacteria is outpacing the development of new antibiotics. The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas ae
Externí odkaz:
https://doaj.org/article/621c4d523ad043d8940f0e1b6d31b7f4
Autor:
Chao Lei, Jingyao Mu, Yun Teng, Liqing He, Fangyi Xu, Xiangcheng Zhang, Kumaran Sundaram, Anil Kumar, Mukesh K. Sriwastva, Matthew B. Lawrenz, Lifeng Zhang, Jun Yan, Wenke Feng, Craig J. McClain, Xiang Zhang, Huang-Ge Zhang
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101571- (2020)
Summary: Clostridioides difficile (C. diff) is the leading cause of antibiotic-associated colitis. Here, we report that lemon exosome-like nanoparticles (LELNs) manipulated probiotics to inhibit C. diff infection (CDI). LELN-manipulated Lactobacillus
Externí odkaz:
https://doaj.org/article/6828d49f0d0149b3964486692b400d20
Autor:
Christopher Duplessis, Jonathan M. Warawa, Matthew B. Lawrenz, Matthew Henry, Biswajit Biswas
Publikováno v:
Antibiotics, Vol 10, Iss 8, p 946 (2021)
Background: Pseudomonas aeruginosa (PsA) is a common etiology of bacteria-mediated lower respiratory tract infections, including pneumonia, hospital acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP). Given the paucity of novel antib
Externí odkaz:
https://doaj.org/article/ab97a5dc79ee49e69f8fea61cd4f7b28
Autor:
W. Ryan Will, Peter Brzovic, Isolde Le Trong, Ronald E. Stenkamp, Matthew B. Lawrenz, Joyce E. Karlinsey, William W. Navarre, Kara Main-Hester, Virginia L. Miller, Stephen J. Libby, Ferric C. Fang
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Gene duplication and subsequent evolutionary divergence have allowed conserved proteins to develop unique roles. The MarR family of transcription factors (TFs) has undergone extensive duplication and diversification in bacteria, where they a
Externí odkaz:
https://doaj.org/article/6e89773f3ee944aa996a1cf09ab4bf04
Autor:
Michael G. Connor, Amanda R. Pulsifer, Donghoon Chung, Eric C. Rouchka, Brian K. Ceresa, Matthew B. Lawrenz
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Yersinia pestis has evolved many strategies to evade the innate immune system. One of these strategies is the ability to survive within macrophages. Upon phagocytosis, Y. pestis prevents phagolysosome maturation and establishes a modified co
Externí odkaz:
https://doaj.org/article/ebf5230a7fe84bf694570a581c136c84
Autor:
Tiva T. VanCleave, Amanda R. Pulsifer, Michael G. Connor, Jonathan M. Warawa, Matthew B. Lawrenz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The study of intracellular bacterial pathogens in cell culture hinges on inhibiting extracellular growth of the bacteria in cell culture media. Aminoglycosides, like gentamicin, were originally thought to poorly penetrate eukaryotic cells, and thus,
Externí odkaz:
https://doaj.org/article/86d728a8bfff4d94b1a907ef6ebf162c
Autor:
Amanda Brady, Amanda R. Pulsifer, Sarah L. Price, Katelyn R. Sheneman, Krishna Rao Maddipati, Sobha R. Bodduluri, Jianmin Pan, Shesh N. Rai, Bodduluri Haribabu, Silvia M. Uriarte, Matthew B. Lawrenz
Subverting the host immune response to inhibit inflammation is a key virulence factor ofYersinia pestis. The inflammatory cascade is tightly controlled via the sequential action of lipid and protein mediators of inflammation. Because delayed inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1584eb100ffb382d4de400a0441b015
https://doi.org/10.1101/2023.03.13.532349
https://doi.org/10.1101/2023.03.13.532349
Autor:
Vivekanandan Subramanian, Michael H. Lee, Daniel Petras, William Santus, Walter J. Chazin, Benjamin A. Gilston, Robert D. Perry, Sean Treacy-Abarca, Keith D. Green, Evelyn M. Hoover, Romana R. Gerner, Sarah L. Price, Pieter C. Dorrestein, Hannah Hillman, Eric P. Skaar, Sylvie Garneau-Tsodikova, Sean Paul Nuccio, Joshua Tjokrosurjo, Jose Camacho, Janet Z. Liu, Matthew B. Lawrenz, Hui Zhi, Judith Behnsen, Nicola P. Montaldo, Manuela Raffatellu, Allegra T. Aron
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Zinc is an essential cofactor for bacterial metabolism, and many Enterobacteriaceae express the zinc transporters ZnuABC and ZupT to acquire this metal in the host. However, the probiotic bacterium Escherichia coli Nissle 1917 (or “Nissle”) exhib