Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Matthew B. Kilgore"'
Autor:
Delaney K Geitgey, Miyoung Lee, Kirsten A Cottrill, Maya Jaffe, William Pilcher, Swati Bhasin, Jessica Randall, Anthony J Ross, Michelle Salemi, Marisol Castillo-Castrejon, Matthew B Kilgore, Ayjha C Brown, Jeremy M Boss, Rich Johnston, Anne M Fitzpatrick, Melissa L Kemp, Robert English, Eric Weaver, Pritha Bagchi, Ryan Walsh, Christopher D Scharer, Manoj Bhasin, Joshua D Chandler, Karmella A Haynes, Elizabeth A Wellberg, Curtis J Henry
Publikováno v:
JNCI Monographs. 2023:12-29
The obesity pandemic currently affects more than 70 million Americans and more than 650 million individuals worldwide. In addition to increasing susceptibility to pathogenic infections (eg, SARS-CoV-2), obesity promotes the development of many cancer
Autor:
Matthew B. Kilgore, Dimitrios Platis, Timothy Lim, Samantha Isenberg, C. Austin Pickens, Carla Cuthbert, Konstantinos Petritis
Publikováno v:
Analytical Chemistry. 95:3187-3194
Autor:
Hamed Horati, Bob J. Scholte, Camilla Margaroli, M. Veltman, Jeffrey Chou, Matthew B. Kilgore, Marta Stolarczyk, Hettie M. Janssens, Harm A.M.W. Tiddens, Joshua D. Chandler, Limin Peng, Rabindra Tirouvanziam
Publikováno v:
Journal of Cystic Fibrosis, 19(6), 902-909. Elsevier
J Cyst Fibros
J Cyst Fibros
BACKGROUND: Previously, we showed that abnormal levels of bioactive lipids in bronchoalveolar lavage fluid (BALF) from infants with cystic fibrosis (CF) correlated with early structural lung damage. METHOD: To extend these studies, BALF bioactive lip
Autor:
Balázs Rada, Ralph A. Tripp, Nuha Milad Asthiwi, Ted M. Ross, Joshua D. Chandler, Aaron D. Gingerich, Tamas Nagy, Jeffrey W Ecker, Demba Sarr, Matthew B. Kilgore, Giuseppe A. Sautto, Faris Almutairi
Publikováno v:
Proc Natl Acad Sci U S A
Dual oxidase 1 (DUOX1) is an NADPH oxidase that is highly expre-ssed in respiratory epithelial cells and produces H2O2 in the airway lumen. While a line of prior in vitro observations suggested that DUOX1 works in partnership with an airway peroxidas
Autor:
Matthew B Kilgore, Megan M Augustin, Courtney M Starks, Mark O'Neil-Johnson, Gregory D May, John A Crow, Toni M Kutchan
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103223 (2014)
Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum). Despite its importa
Externí odkaz:
https://doaj.org/article/5c7da27cb86049a3b775279f7571edce
Publikováno v:
ChemBioChem. 19:1849-1852
Numerous short-chain dehydrogenases/reductases (SDRs) have found biocatalytic applications in C=O and C=C (enone) reduction. For NADPH-dependent C=N reduction, imine reductases (IREDs) have primarily been investigated for extension of the substrate r
Autor:
Benjamin R. Lichman, C. Robin Buell, Carlos E. Rodríguez-López, Pamela S. Soltis, Evgeny V. Mavrodiev, Benoît Boachon, Mohamed O. Kamileen, Emily Crisovan, Laura K Henry, Douglas E. Soltis, Dongyan Zhao, Matthew B. Kilgore, Brieanne Vaillancourt, Krystle Wiegert-Rininger, Natalia Dudareva, Sarah E. O'Connor, Linsey Newton, Heather R. Kates, Grant T. Godden, Nicolás García
Publikováno v:
Molecular Plant. 11:1084-1096
The evolution of chemical complexity has been a major driver of plant diversification, with novel compounds serving as key innovations. The species-rich mint family (Lamiaceae) produces an enormous variety of compounds that act as attractants and def
Autor:
Brian J. Day, Matthew B. Kilgore, Elysia Min, Preston E. Bratcher, Robert J. Hondal, Joshua D. Chandler, David P. Nichols, John J. LiPuma
Publikováno v:
Free Radic Biol Med
A hallmark of cystic fibrosis (CF) lung pathology is an increased susceptibility to pulmonary infections. Thiocyanate ((−)SCN) is an endogenous component of the innate immunity’s peroxidase system that converts (−)SCN to the antimicrobial agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d205d4d6ec1aa4c8d403eb7bbf6e0e2
https://europepmc.org/articles/PMC6951815/
https://europepmc.org/articles/PMC6951815/
Publikováno v:
Journal of Biological Chemistry. 291:16740-16752
Amaryllidaceae alkaloids are a large group of plant natural products with over 300 documented structures and diverse biological activities. Several groups of Amaryllidaceae alkaloids including the hemanthamine- and crinine-type alkaloids show promise
Autor:
Matthew B. Kilgore, Toni M. Kutchan
Publikováno v:
Phytochemistry Reviews. 15:317-337
Amaryllidaceae alkaloids are an example of the vast diversity of secondary metabolites with great therapeutic promise. The identification of novel compounds in this group with over 300 known structures continues to be an area of active study. The rec