Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Matthew B Nodwell"'
Autor:
Emma K. Davison, David A. Petrone, Michael Meanwell, Matthew B. Nodwell, Steven M. Silverman, Louis-Charles Campeau, Robert Britton
Publikováno v:
Nature Protocols. 17:2008-2024
Autor:
Cohan Huxley, Callum Lucas, Juan Manuel Mesa Bruno, Matthew J. Anketell, Emma K. Davison, Garrett Muir, Matthew B. Nodwell, Michael Meanwell, Steven M. Silverman, Robert Britton, Louis-Charles Campeau
Publikováno v:
Canadian Journal of Chemistry.
α-heteroaryl acetaldehydes have become important building blocks in the synthesis of synthetic nucleosides. Novel organocatalytic cascades have enabled the rapid generation of nucleosides, which are valuable building blocks in the development of ant
Autor:
Josiah J. Newton, Gökçe Engüdar, Alan J. Brooke, Matthew B. Nodwell, Holly Horngren‐Rhodes, Rainer E. Martin, Paul Schaffer, Robert Britton, Chadron M. Friesen
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Josiah J, Newton, Gökçe, Engüdar, Alan J, Brooke, Matthew B, Nodwell, Holly, Horngren-Rhodes, Rainer E, Martin, Paul, Schaffer, Robert, Britton, Chadron M, Friesen
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany).
The difluoromethyl group plays an important role in modern medicinal and agrochemistry. While several difluoromethylation reagents have been reported, these typically rely on difluoromethyl carbenes or anions, or target specific processes. Here, we d
Autor:
Matthew B. Nodwell, Robert Britton
Publikováno v:
ACS Infectious Diseases. 7:153-161
A solid-phase platform for the precise and sequential synthesis of enterobactin analogues is described. This chemistry unites the power of solid-phase peptide synthesis with the unique opportunities and applications offered by siderophore chemistry.
Autor:
Emma K, Davison, David A, Petrone, Michael, Meanwell, Matthew B, Nodwell, Steven M, Silverman, Louis-Charles, Campeau, Robert, Britton
Publikováno v:
Nature protocols. 17(9)
Nucleoside analogs are valuable commodities in the development of antisense oligonucleotides or as stand-alone antiviral and anticancer therapies. Syntheses of nucleoside analogs are typically challenged by a reliance on chiral pool starting material
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
The illudin natural product family are fungal secondary metabolites with a characteristic spirocyclopropyl‐substituted fused 6,5‐bicyclic ring system. They have been extensively studied for their cytotoxicity in various tumor cell types, and semi
Autor:
Hua Yang, Milena Čolović, Helen Merkens, Bjoern Wagner, Paul Schaffer, Francois Benard, Noeen Malik, Robert Britton, Rainer E. Martin, Matthew B. Nodwell
Publikováno v:
Journal of Nuclear Medicine. 60:1003-1009
1003 Introduction: Target specificity is one of the main goals when developing new specific agents for oncological diagnosis and therapy. Animal experiments with xenografts mostly in mice are usually performed to obtain information about target speci
Autor:
Hua Yang, Zheliang Yuan, Rainer E. Martin, Helen Merkens, Paul Schaffer, Noeen Malik, Francois Benard, Robert Britton, Matthew B. Nodwell
Publikováno v:
Angewandte Chemie International Edition. 57:12733-12736
Peptides are often ideal ligands for diagnostic molecular imaging due to their ease of synthesis and tuneable targeting properties. However, labelling unmodified peptides with 18 F for positron emission tomography (PET) imaging presents a number of c
Autor:
Zheliang Yuan, Matthew B. Nodwell, Hua Yang, Noeen Malik, Helen Merkens, François Bénard, Rainer E. Martin, Paul Schaffer, Robert Britton
Publikováno v:
Angewandte Chemie. 130:12915-12918