Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Matthew B, Lohse"'
Autor:
Matthew B. Lohse, Matthew T. Laurie, Sophia Levan, Naomi Ziv, Craig L. Ennis, Clarissa J. Nobile, Joseph DeRisi, Alexander D. Johnson
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT The fungal pathogen Candida auris represents a severe threat to hospitalized patients. Its resistance to multiple classes of antifungal drugs and ability to spread and resist decontamination in healthcare settings make it especially dangerou
Externí odkaz:
https://doaj.org/article/7efea5b75ed74a6cb9b306e35de5138f
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280233 (2023)
Candida albicans is a normal member of the human microbiome and an opportunistic fungal pathogen. This species undergoes several morphological transitions, and here we consider white-opaque switching. In this switching program, C. albicans reversibly
Externí odkaz:
https://doaj.org/article/58214c7296bc4f158fcb43c84a6f11de
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 8, Pp 2593-2600 (2020)
The fungal species Candida albicans is both a member of the human microbiome and a fungal pathogen. C. albicans undergoes several different morphological transitions, including one called white-opaque switching. Here, cells reversibly switch between
Externí odkaz:
https://doaj.org/article/12736848f06540d29fb2988f4f23a2a2
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Biofilms formed by the fungal pathogen Candida albicans are resistant to many of the antifungal agents commonly used in the clinic. Previous reports suggest that protease inhibitors, specifically inhibitors of aspartyl proteases, could be effective a
Externí odkaz:
https://doaj.org/article/574825e8f6d74f4fafe9bdada0cf5549
Autor:
Matthew B. Lohse, Alexander D. Johnson
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 3, Pp 721-729 (2016)
The human fungal pathogen Candida albicans can switch between two cell types, “white” and “opaque,” each of which is heritable through many cell divisions. Switching between these two cell types is regulated by six transcriptional regulators
Externí odkaz:
https://doaj.org/article/13cb65558dbf4248b784db07a67e63d6
Autor:
Matthew B. Lohse, Matthew T. Laurie, Sophia Levan, Naomi Ziv, Craig L. Ennis, Clarissa J. Nobile, Joseph DeRisi, Alexander D. Johnson
Publikováno v:
bioRxiv
The fungal pathogenCandida aurisrepresents a severe threat to hospitalized patients. Its resistance to multiple classes of antifungal drugs and ability to spread and resist decontamination in health-care settings make it especially dangerous. We scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9860e23a9683adb6590f6c2d96d0a09a
https://doi.org/10.1101/2023.02.16.528905
https://doi.org/10.1101/2023.02.16.528905
Publikováno v:
Journal of Fungi, Vol 7, Iss 1, p 9 (2020)
The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molec
Externí odkaz:
https://doaj.org/article/ceec82b2e02947d3a4ec901e1043cbea
Publikováno v:
Microorganisms, Vol 8, Iss 5, p 756 (2020)
Biofilms formed by the human fungal pathogen Candida albicans are naturally resistant to many of the antifungal agents commonly used in the clinic. We screened a library containing 1600 clinically tested drug compounds to identify compounds that inhi
Externí odkaz:
https://doaj.org/article/4dd7ed3fc3cf419fb651ef7e5e70faaf
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218037 (2019)
Candida albicans, a species of fungi, can thrive in diverse niches of its mammalian hosts; it is a normal resident of the GI tract and mucosal surfaces but it can also enter the bloodstream and colonize internal organs causing serious disease. The ab
Externí odkaz:
https://doaj.org/article/492f11baa1174bcb9cb0dad138482e54
Autor:
Iuliana V. Ene, Matthew B. Lohse, Adrian V. Vladu, Joachim Morschhäuser, Alexander D. Johnson, Richard J. Bennett
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT The white-opaque switch is a bistable, epigenetic transition affecting multiple traits in Candida albicans including mating, immunogenicity, and niche specificity. To compare how the two cell states respond to external cues, we examined the
Externí odkaz:
https://doaj.org/article/d6317922d0f9460fb24513632b548dce