Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthew B, Barajas"'
Autor:
Matthew B. Barajas, Takuro Oyama, Masakazu Shiota, Zhu Li, Maximillian Zaum, Ilija Zecevic, Matthias L. Riess
Publikováno v:
Cells, Vol 13, Iss 12, p 1047 (2024)
Background: Ischemic post-conditioning (IPoC) has been shown to improve outcomes in limited pre-clinical models. As down-time is often unknown, this technique needs to be investigated over a range of scenarios. As this tool limits reperfusion injury,
Externí odkaz:
https://doaj.org/article/e9dbcc8fb35247aab6f988945a9e4e71
Publikováno v:
Physiological Reports, Vol 10, Iss 15, Pp n/a-n/a (2022)
Abstract Infants and children are vulnerable to developing propofol infusion syndrome (PRIS) and young age is a risk factor. Cardiac involvement is often prominent and associated with death. However, the mechanisms of pediatric PRIS are poorly unders
Externí odkaz:
https://doaj.org/article/46bde05e66ae453fa4274751c28687f0
Autor:
Zhu Li, Mukesh K. Gupta, Matthew B. Barajas, Takuro Oyama, Craig L. Duvall, Matthias L. Riess
Publikováno v:
Cells, Vol 12, Iss 10, p 1394 (2023)
Reperfusion after ischemia causes additional cellular damage, known as reperfusion injury, for which there is still no effective remedy. Poloxamer (P)188, a tri-block copolymer-based cell membrane stabilizer (CCMS), has been shown to provide protecti
Externí odkaz:
https://doaj.org/article/66723ba96b4b483e98f010c613e7889a
Autor:
Ryan J. Lefevre, Matthew B. Barajas, Claudius Balzer, Franz J. Baudenbacher, Matthias L. Riess, Genevieve Staudt, Antonio Hernandez, Susan S. Eagle
Publikováno v:
Pediatric Research. 93:1539-1545
Publikováno v:
Pediatric Research. 92:1341-1349
Background Propofol infusion syndrome (PRIS) is a potentially lethal consequence of long-term propofol administration. Children are vulnerable and cardiac involvement is often prominent and associated with mortality. We aimed to determine the mechani
Autor:
Matthias L. Riess, Matthew B. Barajas
Publikováno v:
Journal of Visualized Experiments.
Autor:
Richard J. Levy, Matthew B. Barajas
Publikováno v:
Journal of Visualized Experiments.
The use of the ex-vivo retrograde perfused heart has long been a cornerstone of ischemia-reperfusion investigation since its development by Oskar Langendorff over a century ago. Although this technique has been applied to mice over the last 25 years,
Publikováno v:
International Journal of Molecular Sciences. 24:3334
Traumatic brain injury (TBI) is a significant cause of morbidity and mortality worldwide. Varied mechanisms of injury contribute to the heterogeneity of this patient population as demonstrated by the multiple published grading scales and diverse requ
Publikováno v:
Circulation. 144
Introduction: Cardiovascular disease remains one of the leading causes of complications and death worldwide. Therefore, accurate and reliable methods of mimicking ischemia/reperfusion (IR) injury in cardiac cells in vivo are crucial when testing drug
Publikováno v:
Circulation. 144
Reperfusion restores blood flow after myocardial ischemia but can cause additional cellular injury by the sudden reintroduction of oxygen and nutrients. There is still no effective remedy for myocardial ischemia/reperfusion (IR) injury. Our previous