Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthew A.H. Parson"'
Publikováno v:
Biochemical Society transactions.
A large amount of the human proteome is composed of highly dynamic regions that do not adopt a single static conformation. These regions are defined as intrinsically disordered, and they are found in a third of all eukaryotic proteins. They play inst
Autor:
Alexandria L. Shaw, Matthew A.H. Parson, Linda Truebestein, Meredith L. Jenkins, Thomas A. Leonard, John E. Burke
Publikováno v:
Structure. 31:343-354.e3
Autor:
Elizabeth Conibear, Tamas Balla, Péter Várnai, Meredith L. Jenkins, Anne-Claude Gingras, Matthew A.H. Parson, Nicole St-Denis, John E. Burke, Idil Ulengin-Talkish, Gergo Gulyas, Alexis Z. L. Shih, Martha S. Cyert, Jagoree Roy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Calcineurin, the conserved protein phosphatase and target of immunosuppressants, is a critical mediator of Ca2+ signaling. Here, to discover calcineurin-regulated processes we examined an understudied isoform, CNAβ1. We show that unlike canonical cy
Autor:
Matthew C. Thibodeau, Noah J. Harris, Meredith L. Jenkins, Matthew A.H. Parson, John T. Evans, Mackenzie K. Scott, Alexandria L. Shaw, Daniel Pokorný, Thomas A. Leonard, John E. Burke
Publikováno v:
Journal of Biological Chemistry. 299:102764
The formation of complexes between Rab11 and its effectors regulates multiple aspects of membrane trafficking, including recycling and ciliogenesis. WD repeat-containing protein 44 (WDR44) is a structurally uncharacterized Rab11 effector that regulat
Autor:
Brendon J. Medley, Leif Leclaire, Nicole Thompson, Keira E. Mahoney, Benjamin Pluvinage, Matthew A.H. Parson, John E. Burke, Stacy Malaker, Warren Wakarchuk, Alisdair B. Boraston
Publikováno v:
Journal of Biological Chemistry. 298:102439
Akkermansia muciniphila is key member of the human gut microbiota that impacts many features of host health. A major characteristic of this bacterium is its interaction with host mucin, which is abundant in the gut environment, and its ability to met
Autor:
Jagoree Roy, John E. Burke, Alexis Z. L. Shih, Anne-Claude Gingras, Péter Várnai, Nicole St-Denis, Gergo Gulyas, Meredith L. Jenkins, Tamas Balla, Elizabeth Conibear, Martha S. Cyert, Matthew A.H. Parson, Idil Ulengin-Talkish
Calcineurin, the conserved protein phosphatase and target of immunosuppressants, is a critical mediator of Ca2+ signaling. To discover novel calcineurin-regulated processes we examined an understudied isoform, CNAβ1. We show that unlike canonical cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6bff6339c4327f4a491d03cb31fd38
https://doi.org/10.1101/2021.07.14.451536
https://doi.org/10.1101/2021.07.14.451536
Autor:
Sung-Eun Nam, Meredith L. Jenkins, Matthew A.H. Parson, John E. Burke, Kaelin D. Fleming, Udit Dalwadi, Calvin K. Yip, Noah J Harris
Publikováno v:
Journal of molecular biology. 433(18)
Transport Protein Particle complexes (TRAPP) are evolutionarily conserved regulators of membrane trafficking, with this mediated by their guanine nucleotide exchange factor (GEF) activity towards Rab GTPases. In metazoans evidence suggests that two d