Zobrazeno 1 - 10
of 784
pro vyhledávání: '"Matthew A. Wood"'
Autor:
Joel Quinn, Ahmed Salman, Christopher Paluch, Matthew Jackson-Wood, Michelle E. McClements, Jian Luo, Simon J. Davis, Richard J. Cornall, Robert E. MacLaren, Calliope A. Dendrou, Kanmin Xue
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Uveitis is characterised by breakdown of the blood-retinal barrier (BRB), allowing infiltration of immune cells that mediate intraocular inflammation, which can lead to irreversible damage of the neuroretina and the loss of sight. Treatment
Externí odkaz:
https://doaj.org/article/0175e11c5500492d89e09cf2b60bc78f
Autor:
Nicholas Fadell, Flora Laurent, Sai Anusha Sanka, Esther Ochoa, Lauren Yaeger, Xiaowei Li, Matthew D. Wood, Justin M. Sacks, Saif Badran
Publikováno v:
Bioengineering, Vol 11, Iss 10, p 1025 (2024)
Two of the greatest challenges in breast reconstruction are mastectomy skin flap necrosis (MSFN) and autologous flap failure. This review summarizes current evidence regarding the usage of indocyanine green angiography (ICGA) in breast reconstruction
Externí odkaz:
https://doaj.org/article/828f525f47ef4aee959e530bab330853
Autor:
Anna J Kordala, Jessica Stoodley, Nina Ahlskog, Muhammad Hanifi, Antonio Garcia Guerra, Amarjit Bhomra, Wooi Fang Lim, Lyndsay M Murray, Kevin Talbot, Suzan M Hammond, Matthew JA Wood, Carlo Rinaldi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-16 (2023)
Abstract Spinal muscular atrophy (SMA) is a leading genetic cause of infant mortality. The advent of approved treatments for this devastating condition has significantly changed SMA patients' life expectancy and quality of life. Nevertheless, these a
Externí odkaz:
https://doaj.org/article/0a6be327d14849d1ae2a1fc49bf73886
Autor:
Jesús A. Acevedo Cintrón, Daniel A. Hunter, Lauren Schellhardt, Deng Pan, Susan E. Mackinnon, Matthew D. Wood
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6413 (2024)
The use of acellular nerve allografts (ANAs) to reconstruct long nerve gaps (>3 cm) is associated with limited axon regeneration. To understand why ANA length might limit regeneration, we focused on identifying differences in the regenerative and vas
Externí odkaz:
https://doaj.org/article/3d83879e49954af890b40aec535c9c05
Autor:
David Chi, MD PhD, Sai L. Pinni, BS, Dan A. Hunter, RA, Matthew D. Wood, PhD, Susan E. Mackinnon, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss S4, Pp 48-49 (2024)
Externí odkaz:
https://doaj.org/article/bfdae6c7d353455797c3fcba248e4463
Autor:
Sai L. Pinni, BS, Michael J. Finnan, MD, Lauren Schellhardt, BS, Alison K. Snyder-Warwick, MD, Susan E. Mackinnon, MD, Matthew D. Wood, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss S4, Pp 116-116 (2024)
Externí odkaz:
https://doaj.org/article/a36208e74e4f44d2b07fffdf7ceea81b
Autor:
Sarah J. Overby, Estefanía Cerro-Herreros, Irene González-Martínez, Miguel A. Varela, David Seoane-Miraz, Yahya Jad, Richard Raz, Thorleif Møller, Manuel Pérez-Alonso, Matthew J. Wood, Beatriz Llamusí, Rubén Artero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1146-1155 (2022)
Myotonic dystrophy type 1 is a debilitating neuromuscular disease causing muscle weakness, myotonia, and cardiac dysfunction. The phenotypes are caused by muscleblind-like (MBNL) protein sequestration by toxic RNA in the DM1 protein kinase (DMPK) gen
Externí odkaz:
https://doaj.org/article/83c3274632db47e987f7a53bbf571513
Autor:
Elaine S Rogers, Rita Sasidharan, Graeme M Sequeira, Matthew R Wood, Stephen P Bird, Justin W L Keogh, Bruce Arroll, Joanna Stewart, Roderick D MacLeod
Publikováno v:
Journal of Health Science and Medical Research (JHSMR), Vol 40, Iss 3, Pp 335-347 (2022)
Objective: Cancer cachexia is defined as: a ‘multifactorial syndrome’, and it has been suggested that a multitargeted approach is required in its management. High prevalence is seen within non-small cell lung cancer, and patients may continue to
Externí odkaz:
https://doaj.org/article/1dbd12d4e4714279a76fd7fce752e3c2
Autor:
Estefanía Cerro-Herreros, Irene González-Martínez, Nerea Moreno, Jorge Espinosa-Espinosa, Juan M. Fernández-Costa, Anna Colom-Rodrigo, Sarah J. Overby, David Seoane-Miraz, Javier Poyatos-García, Juan J. Vilchez, Adolfo López de Munain, Miguel A. Varela, Matthew J. Wood, Manuel Pérez-Alonso, Beatriz Llamusí, Rubén Artero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 174-191 (2021)
Myotonic dystrophy type 1 (DM1) is a rare neuromuscular disease caused by expansion of unstable CTG repeats in a non-coding region of the DMPK gene. CUG expansions in mutant DMPK transcripts sequester MBNL1 proteins in ribonuclear foci. Depletion of
Externí odkaz:
https://doaj.org/article/fcb1590ef3cd430fb37c123264dbacdc
Autor:
Fiona Cooke, Mary Neal, Matthew J. Wood, I. Jolanda M. de Vries, Amy E. Anderson, Julie Diboll, Arthur G. Pratt, James Stanway, Ioana Nicorescu, Nicholas Moyse, Dawn Hiles, David Caulfield, Anne M. Dickinson, Andrew M. Blamire, Pete Thelwall, John D. Isaacs, Catharien M. U. Hilkens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tolerogenic dendritic cell (tolDC) therapies aim to restore self-tolerance in patients suffering from autoimmune diseases. Phase 1 clinical trials with tolDC have shown the feasibility and safety of this approach, but have also highlighted a lack of
Externí odkaz:
https://doaj.org/article/47a487e2cf1e43fca48e6bf3f7d8fb41