Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Matthew A. Spence"'
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 4 (2024)
Clostridioides difficile infection (CDI) threatens vulnerable populations in health care. Two-step testing improves specificity, avoiding over-treatment. This study analyzed inpatient records to estimate diagnostic outcomes and identify characteristi
Externí odkaz:
https://doaj.org/article/09b2bd3b769b4b9087a8ad6fa4258168
Publikováno v:
eLife, Vol 11 (2022)
Ribonucleotide reductases (RNRs) are used by all free-living organisms and many viruses to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are remarkably diverse by primary sequence and cofactor requirement, while shari
Externí odkaz:
https://doaj.org/article/9f0ce5417e2e4074ab09de6438752a99
Autor:
Vito Thijssen, Daniel L. Hurdiss, Oliver J. Debski-Antoniak, Matthew A. Spence, Charlotte Franck, Alexander Norman, Anupriya Aggarwal, Nadia J. Mokiem, David A. A. van Dongen, Stein W. Vermeir, Minglong Liu, Wentao Li, Marianthi Chatziandreou, Tim Donselaar, Wenjuan Du, Ieva Drulyte, Berend-Jan Bosch, Joost Snijder, Stuart Turville, Richard J. Payne, Colin J. Jackson, Frank J. M. van Kuppeveld, Seino A. K. Jongkees
The ongoing COVID-19 pandemic has had great societal and health consequences. Despite the availability of vaccines, infection rates remain high due to immune evasive Omicron sublineages. Broad-spectrum antivirals are needed to safeguard against emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bef323aac59161513088436e62791ac
https://dspace.library.uu.nl/handle/1874/429162
https://dspace.library.uu.nl/handle/1874/429162
This upload conatins the raw fastq files for the manuscript "Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors". Deep sequencing was used to evaluate presorted and repressed sorted LacI-GalR Family (LGF) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f8e9d3e0c84e96c544c11300f3c2fe
Autor:
Yvonne Joho, Vanessa Vongsouthi, Matthew A. Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A. Kaczmarski, Alessandro T. Caputo, Santana Royan, Colin J. Jackson, Albert Ardevol
Publikováno v:
Biochemistry. 62:437-450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c14861a22a61346712f8708e47df1f8
https://doi.org/10.1021/acs.biochem.2c00323
https://doi.org/10.1021/acs.biochem.2c00323
Publikováno v:
Protein science : a publication of the Protein Society. 31(12)
Ribonucleotide reductases (RNRs) are used by all free-living organisms and many viruses to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are remarkably diverse by primary sequence and cofactor requirement, while shari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47701574ec38828214561e05789433f5
https://pubmed.ncbi.nlm.nih.gov/36307939
https://pubmed.ncbi.nlm.nih.gov/36307939
Publikováno v:
eLife. 11
Ribonucleotide reductases (RNRs) are used by all free-living organisms and many viruses to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are remarkably diverse by primary sequence and cofactor requirement, while shari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb1024143e99a37a86a40c726af41a6
https://doi.org/10.7554/elife.79790
https://doi.org/10.7554/elife.79790
Publikováno v:
Cell Systems. 13:271-273
Understanding how protein sequences have evolved is one of the defining challenges in modern biology. In this issue of Cell Systems, Hie et al. describe a novel phylogenetic approach, dubbed "evo-velocity," that exploits protein language modeling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d4658781fbcdd905eba3d950846c67
https://doi.org/10.1016/j.cels.2022.03.004
https://doi.org/10.1016/j.cels.2022.03.004
Ribonucleotide reductases (RNRs) are used by all organisms and many viruses to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are remarkably diverse by primary sequence and cofactor requirement, while sharing a conserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28959b0e90462ad8a45db1d228182051
https://doi.org/10.1101/2022.04.23.489257
https://doi.org/10.1101/2022.04.23.489257