Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Matthew A. Simon"'
Autor:
Shivali Patel, Alec N. Sexton, Madison S. Strine, Craig B. Wilen, Matthew D. Simon, Anna Marie Pyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Compact RNA structural motifs control many aspects of gene expression, but we lack methods for finding these structures in the vast expanse of multi-kilobase RNAs. To adopt specific 3-D shapes, many RNA modules must compress their RNA backbo
Externí odkaz:
https://doaj.org/article/222cbbdf4c56429296e795df9d118c31
Autor:
Yimeng Gao, Joshua T. Zimmer, Radovan Vasic, Chengyang Liu, Rana Gbyli, Shu-Jian Zheng, Amisha Patel, Wei Liu, Zhihong Qi, Yaping Li, Raman Nelakanti, Yuanbin Song, Giulia Biancon, Andrew Z. Xiao, Sarah Slavoff, Richard G. Kibbey, Richard A. Flavell, Matthew D. Simon, Toma Tebaldi, Hua-Bing Li, Stephanie Halene
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113163- (2023)
Summary: N6-methyladenosine (m6A) RNA modification controls numerous cellular processes. To what extent these post-transcriptional regulatory mechanisms play a role in hematopoiesis has not been fully elucidated. We here show that the m6A demethylase
Externí odkaz:
https://doaj.org/article/18f048077b4b40258f667dc818d9c471
Autor:
Jeremy L. May, Steven F. Oberbauer, Steven L. Unger, Matthew J. Simon, Katlyn R. Betway, Robert D. Hollister
Publikováno v:
Arctic Science, Vol 8, Iss 3, Pp 967-978 (2022)
Increases in shrub growth and canopy cover are well documented community responses to climate warming in the Arctic. An important consequence of larger deciduous shrubs is shading of prostrate plant species, many of which are important sources of nec
Externí odkaz:
https://doaj.org/article/026b37a03e5847d4a755972f52ab3642
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0263434 (2022)
Little is known of the relationship between exposure to the smallest particles of air pollution and socio-demographic characteristics. This paper explores linkages between ultrafine particle (UFP) concentrations and indicators of both race/ethnicity
Externí odkaz:
https://doaj.org/article/8fabddd0def248e8981b4c27edff75d2
Autor:
Christopher T. Sciria, Edward V. Kogan, Ari G. Mandler, Ilhwan Yeo, Matthew S. Simon, Luke K. Kim, James E. Ip, Christopher F. Liu, Steven M. Markowitz, Bruce B. Lerman, George Thomas, Jim W. Cheung
Publikováno v:
Journal of the American College of Cardiology. 81:1714-1725
Publikováno v:
Trends in Cell Biology. 33:324-339
Loss-of-function heterozygous mutations in GRN, the gene encoding progranulin (PGRN), were identified in patients with frontotemporal lobar degeneration (FTLD) almost two decades ago and are generally linked to reduced PGRN protein expression levels.
Autor:
Laura Corlin, Mark Woodin, Jaime E. Hart, Matthew C. Simon, David M. Gute, Joanna Stowell, Katherine L. Tucker, John L. Durant, Doug Brugge
Publikováno v:
Environmental Health, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Few longitudinal studies have examined the association between ultrafine particulate matter (UFP, particles
Externí odkaz:
https://doaj.org/article/f6705bf453e8417ea5aaa2b78144352c
Autor:
Steven Unger, S. F. Oberbauer, Matthew J. Simon, Katlyn R. Betway, Jeremy L. May, Robert D. Hollister
Publikováno v:
Arctic Science. 8:967-978
Increases in shrub growth and canopy cover are well documented community responses to climate warming in the Arctic. An important consequence of larger deciduous shrubs is shading of prostrate plant species, many of which are important sources of nec
Autor:
Joshua T. Zimmer, Isaac W. Vock, Jeremy A. Schofield, Lea Kiefer, Michelle H. Moon, Matthew D. Simon
Publikováno v:
bioRxiv
RNA metabolic labeling using 4-thiouridine (s4U) captures the dynamics of RNA synthesis and decay. The power of this approach is dependent on appropriate quantification of labeled and unlabeled sequencing reads, which can be compromised by the appare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2418faec35058c4a0a14e8aba3cd019
https://doi.org/10.1101/2023.05.24.542133
https://doi.org/10.1101/2023.05.24.542133
Autor:
Jake C. Swartzel, Michael J. Bond, Andreas P. Pintado-Urbanc, Mehana Daftary, Mackenzie W. Krone, Todd Douglas, Evan J. Carder, Joshua T. Zimmer, Takahiro Maeda, Matthew D. Simon, Craig M. Crews
Publikováno v:
ACS Chemical Biology. 17:1789-1798
The RNA decapping scavenger protein, DcpS, has recently been identified as a dependency in acute myeloid leukemia (AML). The potent DcpS inhibitor RG3039 attenuates AML cell viability, and shRNA knockdown of DcpS is also antiproliferative. Importantl