Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Matthew A. Gonda"'
Publikováno v:
Biochemistry. 49:6550-6556
Native proteins often lack immunogenicity and thus limit vaccine and mAb development. We described here a unique method to enhance the immunogenicity of native proteins. This is achieved by creating non-native isomers of disulfide proteins (X-isomers
Autor:
Ólafur S. Andrésson, Matthew A. Gonda, Gudmundur Georgsson, Björg Rafnar, Kunio Nagashima, Gregory J. Tobin, Eggert Gunnarsson, Sigurbjörg Torsteinsdóttir
Publikováno v:
Virus Research. 53:107-120
Two different recombinant visna virus (VV) gag -baculoviruses were constructed for the expression of precursor VV Gag in insect cells. Both recombinant Gag viruses expressed proteins migrating on SDS–PAGE at the predicted rate for VV Gag precursor,
Publikováno v:
Virology. 236:307-315
Insect cell expression of the HIV-1 Gag precursor protein by recombinant baculoviruses results in the assembly and budding of noninfectious virus-like particles (VLPs). The VLPs resemble immature virus in ultrastructural morphology and can be purifie
Autor:
Luke A. Pallansch, Steven E. Fong, John D. Greenwood, Anita Mentzer, Lynn Rasmussen, Matthew A. Gonda, Terry D. Copeland, David Derse, Kunio Nagashima, Gregory J. Tobin, James Chadwick Williamson
Publikováno v:
Virology. 233:339-357
cDNAs encoding the bovine immunodeficiency virus (BIV) transactivator gene (tat) were cloned from virally infected cells and characterized. BIV expresses two distincttatmRNAs composed of three exons that are derived by alternative splicing. The BIV t
Autor:
Karen Coats, Bruce F. Jenny, D. Gene Luther, Jane K. Battles, Matthew A. Gonda, R. W. Storts, Phillip G. Hoyt, T.G. Snider
Publikováno v:
Veterinary Clinics of North America: Food Animal Practice. 13:151-176
The principal diseases associated with bovine immunodeficiency virus (BlV) infection in a production dairy were bacterial infections. The infections were associated with histologic evidence of compromise of the immune system. The disease were most ap
Publikováno v:
Antiviral Research. 33:21-31
The bovine immunodeficiency virus (BIV) and human immunodeficiency virus types 1 and 2 (HIV-1 and -2) are members of the lentivirus genus of retroviruses. Although DNA sequences of these viruses have diverged considerably, the BIV genome organization
Autor:
Uriel Blas-Machado, B.F. Jenny, Matthew A. Gonda, Jane K. Battles, Phillip G. Hoyt, J. Balady, D.G. Luther, T.G. Snider, Willis H. Ennis, T. X. Lemarchand
Publikováno v:
Comparative Immunology, Microbiology and Infectious Diseases. 19:117-131
Encephalitis, lymphoid tissue depletion and secondary infections occurred over a 5-yr-period in Holstein cows infected with bovine immunodeficiency virus (BIV). There were 59 cattle studied, the majority during 1991, when a severe environmental stres
Autor:
Jerrold M. Ward, Robert H. Wiltrout, Akiko Kojima, Kunio Nagashima, Thomas J. Sayers, Kenji Kaneda, Theresa A. Wiltrout, Craig W. Reynolds, John R. Ortaldo, Matthew A. Gonda, Anne M. Pilaro
Publikováno v:
Biomedical Research. 17:53-65
Autor:
Judy A. Mikovits, Matthew A. Gonda, Luke A. Pallansch, Francis W. Ruscetti, Steven E. Fong, Carol Lackman-Smith
Publikováno v:
Virology. 209(2):604-614
Functional cis-acting regulatory elements in the bovine immunodeficiency virus (BIV) long terminal repeat (LTR) were identified by deletion mapping and nuclear protein gel shift analysis using three BIV-infectible cell lines, Cf2Th, BLAC-20, and EREp
Autor:
Raoul E. Benvensite, Cathi V. George, Kunio Nagashima, Joseph G. Tully, Floyd E. Dewhirst, James G. Fox, Bruce J. Paster, Jerrold M. Ward, Diana C. Haines, Lucy M. Anderson, Raymond V. Gilden, Jerry M. Rice, Robert J. Russell, Peter L. Gorelick, John C. Donovan, Miriam R. Anver, Michael J. Collins, Matthew A. Gonda
Publikováno v:
JNCI Journal of the National Cancer Institute. 86:1222-1227
Background In the autumn of 1992, a novel form of chronic, active hepatitis of unknown etiology was discovered in mice at the National Cancer Institute-Frederick Cancer Research and Development Center (NCI-FCRDC), Frederick, Md. A high incidence of h