Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Matthew A. Cotton"'
Autor:
Bimarzhan Assatova, Christopher Trevisani, Robert Willim, Jessica Duffy, Abner Louissaint, Won-Seog Kim, David J Feith, Thomas Loughran, Foster Powers, Elizabeth A Morgan, Lei Yang, Brandy Pinckney, Garrett Haskett, Matthew J Cotton, Andrew Crabbe, Jessica Beth Ziemba, Ian Brain, Tayla B. Heavican-Foral, Nora Scanlan, Gail Newton, Jaehyuk Choi, Jeffrey A Barnes, Patrick Connor Johnson, Eric D Jacobsen, Steven Greenberg, David M. Weinstock, Salvia Jain
Publikováno v:
Blood. 140:2253-2255
Publikováno v:
Physical review letters. 129(15)
We present a thermodynamically consistent model describing the dynamics of a multi-component mixture where one enzyme component catalyzes a reaction between other components. We find that the catalytic activity alone can induce phase separation for s
Autor:
Tyler R. Koski, Arjun V Pendharkar, Orin Block, Chandrasekaran Jayaraman, Brandon Suleski, A. J. Aranyosi, Yinji Ma, Roozbeh Ghaffari, Nader Dahaleh, Michel Kliot, Yuhao Liu, Lloyd Olson, Bryan Mcgrane, Yadong Zhou, Siyi Ma, Haiwen Luan, Matthew A. Cotton, Arun Jayaraman, Milan Raj, Limei Tian, John A. Rogers, John Wright, Yonggang Huang
Publikováno v:
NPJ digital medicine
npj Digital Medicine, Vol 1, Iss 1, Pp 1-10 (2018)
npj Digital Medicine, Vol 1, Iss 1, Pp 1-10 (2018)
Peripheral nerves are often vulnerable to damage during surgeries, with risks of significant pain, loss of motor function, and reduced quality of life for the patient. Intraoperative methods for monitoring nerve activity are effective, but convention
Autor:
Christopher A. Moskaluk, Michael J. Wick, Matthew J. Cotton, Michael J. Kluk, Shawn M. Gillespie, Kaylyn E. Williamson, William C. Faquin, Christopher D. Carey, Lurdes Queimado, Jun Qi, Russell J.H. Ryan, Yotam Drier, Lynette M. Sholl, Jon C. Aster, Scott J. Rodig, Adel K. El-Naggar, James E. Bradner, A. Afrogheh, Bradley E. Bernstein, Birgit Knoechel
Publikováno v:
Nature genetics
Translocation events are frequent in cancer and may create chimeric fusions or ‘regulatory rearrangements’ that drive oncogene overexpression. Here we identify super-enhancer translocations that drive overexpression of the oncogenic transcription
Autor:
Matthew J. Cotton, Oren Ram, Laura Donohue, Shawn M. Gillespie, Michael B. Cross, Ross L. Levine, Peter van Galen, Brian B. Liau, Bradley E. Bernstein, Russell J.H. Ryan, Yotam Drier, Kaitlin M. Carroll, Aaron D. Viny, Cem Sievers
Publikováno v:
Molecular Cell. 61:170-180
Genome-wide profiling of histone modifications can provide systematic insight into the regulatory elements and programs engaged in a given cell type. However, conventional chromatin immunoprecipitation and sequencing (ChIP-seq) does not capture quant
Autor:
Matthew J. Cotton, Clifford D. Packer
Publikováno v:
Cureus
Enterococcal empyema is a rare complication of pneumonia. We report the case of a 67-year-old asplenic man with pneumonia complicated by respiratory failure and empyema requiring decortication and prolonged chest tube drainage. Cultures of the empyem
Autor:
Matthew J. Cotton, Shawn M. Gillespie, Michael J. Kluk, Mohit Jain, Bradley E. Bernstein, Dale L. Greiner, Daniel S. Pearson, Michael A. Brehm, Serena J. Silver, Manching Ku, Jens G. Lohr, Andrew L. Kung, Federica Piccioni, Alejandro Gutierrez, Daniel Fernandez, Jiang Zhu, Kimberly Stegmaier, Christopher J. Ott, Kaylyn E. Williamson, Hongfang Wang, David E. Root, Michelle A. Kelliher, Jon C. Aster, James E. Bradner, Justine E. Roderick, Birgit Knoechel, Leonard D. Shultz
Publikováno v:
Nature Genetics. 46:364-370
The identification of activating NOTCH1 mutations in T cell acute lymphoblastic leukemia (T-ALL) led to clinical testing of γ-secretase inhibitors (GSIs) that prevent NOTCH1 activation. However, responses to these inhibitors have been transient, sug
Autor:
Matthew J. Cotton, Nicole Birrer, Matthew Meyerson, Daniel Gray, Birgit Knoechel, Yotam Drier, Guangwu Guo, Bang Wong, Noopur Raje, Jesse S. Boehm, Sora Kim, Todd R. Golub, Andrew Yee, Jens G. Lohr, Joshua Gould, Cheng-Zhong Zhang, Gavin Ha
Multiple myeloma (MM) remains an incurable disease, with a treatment-refractory state eventually developing in all patients. Constant clonal evolution and genetic heterogeneity of MM are a likely explanation for the emergence of drug-resistant diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9f07c689d03c0d2aee7fc0f9cf743b
https://europepmc.org/articles/PMC5426804/
https://europepmc.org/articles/PMC5426804/
Autor:
William C. Nelson, Debbie S. Parksey, Michelle L. Gwinn, Jonathan A. Eisen, John F. Heidelberg, J. Craig Venter, Karen A. Ketchum, Robert D. Fleischmann, Vincenzo Scarlato, John Gill, Robert J. Dodson, Haiying Qin, Hervé Tettelin, Robert T. DeBoy, Brian Dougherty, E. Richard Moxon, Jessica Vamathevan, Henry Cittone, Steven L. Salzberg, Nigel J. Saunders, Karen E. Nelson, Anne Ciecko, Li Sun, Hamilton O. Smith, Guido Grandi, Jeremy Peterson, Tanya Mason, Emily B. Clark, Owen White, Derek W. Hood, Claire M. Fraser, Erin Hickey, Eric Blair, T. Utterback, Vega Masignani, Alex C. Jeffries, John F. Peden, Daniel H. Haft, Matthew D. Cotton, Hoda Khouri, Mariagrazia Pizza, Rino Rappuoli
The 2,272,351–base pair genome ofNeisseria meningitidisstrain MC58 (serogroup B), a causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (53.7%) of which were assigned a biological role. Three major islands of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e1d701f5b54d23c893afbb86fc0d32
https://doi.org/10.1126/science.287.5459.1809
https://doi.org/10.1126/science.287.5459.1809
Autor:
Edward B. Fohrman, Dhanesh K. Gupta, Matthew A. Cotton, Katherine S. Gil, John F. Bebawy, Antoun Koht, Srdjan Mirkovic
Publikováno v:
Journal of Clinical Monitoring and Computing. 24:107-111
The purpose of this study was to examine the utility and feasibility of using alternative anterior reference leads when measuring left posterior tibial nerve somatosensory evoked potentials (SEPs). With IRB approval, 12 patients were monitored using