Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew A. Carrigan"'
Autor:
Swellan L. Pinto, Mareike C. Janiak, Gwen Dutyschaever, Marília A. S. Barros, Adrian Guadamuz Chavarria, Maria Pia Martin, Fred Y. Y. Tuh, Carmen Soto Valverde, Lisa M. Sims, Robert M. R. Barclay, Konstans Wells, Nathaniel J. Dominy, Daniel M. A. Pessoa, Matthew A. Carrigan, Amanda D. Melin
Publikováno v:
Royal Society Open Science, Vol 10, Iss 7 (2023)
Dietary variation within and across species drives the eco-evolutionary responsiveness of genes necessary to metabolize nutrients and other components. Recent evidence from humans and other mammals suggests that sugar-rich diets of floral nectar and
Externí odkaz:
https://doaj.org/article/76b67c774e774baeb0f5c60709a9aa2c
Autor:
Matthew A. Carrigan
Publikováno v:
Revista de Química, Vol 30, Iss 1-2 (2016)
Gracias a la resurrección de varias enzimas de nuestros antepasados primates se han identificado varias mutaciones que ocurrieron hace, aproximadamente, 10 millones de años, las cuales le confirieron a nuestros antepasados una capacidad mucho mayor
Externí odkaz:
https://doaj.org/article/8e7f15ec9a5640dda7cc00bcaea87e58
Publikováno v:
Biol Lett
Humans have a long evolutionary relationship with ethanol, pre-dating anthropogenic sources, and possess unusually efficient ethanol metabolism, through a mutation that evolved in our last common ancestor with African great apes. Increased exposure t
Autor:
Matthew A Carrigan, Oleg Uryasev, Ross P Davis, Lanmin Zhai, Thomas D Hurley, Steven A Benner
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41175 (2012)
Gene duplication is a source of molecular innovation throughout evolution. However, even with massive amounts of genome sequence data, correlating gene duplication with speciation and other events in natural history can be difficult. This is especial
Externí odkaz:
https://doaj.org/article/eca419af4e9249cab59d19d803daa036
Autor:
Matthew A. Carrigan
Publikováno v:
Alcohol and Humans
Humans’ long association with alcohol raises questions about both our biological adaptations to handling ethanol and its origins. Fermented foods have less sugar, and require additional detoxification than unfermented versions of the same food, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2f3ce929603c31eb5f1e8cca0946e2
https://doi.org/10.1093/oso/9780198842460.003.0003
https://doi.org/10.1093/oso/9780198842460.003.0003
Autor:
Steven A. Benner, Matthew A. Carrigan, Hyo-Joong Kim, Nicole A. Leal, Shuichi Hoshika, Myong-Jung Kim
Publikováno v:
ACS Synthetic Biology. 4:407-413
Expanding the synthetic biology of artificially expanded genetic information systems (AEGIS) requires tools to make and analyze RNA molecules having added nucleotide "letters". We report here the development of T7 RNA polymerase and reverse transcrip
Autor:
Matthew A. Carrigan
Publikováno v:
Revista de Química; Vol. 30, Núm. 1-2 (2016); 19-22
PUCP-Institucional
Pontificia Universidad Católica del Perú
instacron:PUCP
Revista de Química, Vol 30, Iss 1-2 (2016)
PUCP-Institucional
Pontificia Universidad Católica del Perú
instacron:PUCP
Revista de Química, Vol 30, Iss 1-2 (2016)
We have resurrected ancient enzymes from our primate ancestors and identified several mutations occurring approximately 10 million years ago that endowed our ancestors with an enhanced capacity to metabolize ethanol. This episode of enzyme evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::40886843876f47437d51ca072b87c0a0
http://revistas.pucp.edu.pe/index.php/quimica/article/view/15514/15969
http://revistas.pucp.edu.pe/index.php/quimica/article/view/15514/15969
Publikováno v:
Accounts of Chemical Research. 45:2025-2034
RNA has been called a "prebiotic chemist's nightmare" because of its combination of large size, carbohydrate building blocks, bonds that are thermodynamically unstable in water, and overall intrinsic instability. However, a discontinuous synthesis mo
Autor:
Candace R. Myers, Blair L. Eckman, Carole B. Frye, Thomas D. Hurley, Steven A. Benner, Oleg Uryasev, Matthew A. Carrigan
Paleogenetics is an emerging field that resurrects ancestral proteins from now-extinct organisms to test, in the laboratory, models of protein function based on natural history and Darwinian evolution. Here, we resurrect digestive alcohol dehydrogena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36300ac83938d3c41e2363a134064fbc
https://europepmc.org/articles/PMC4299227/
https://europepmc.org/articles/PMC4299227/
Publikováno v:
Current Opinion in Chemical Biology. 8:672-689
A review of organic chemistry suggests that life, a chemical system capable of Darwinian evolution, may exist in a wide range of environments. These include non-aqueous solvent systems at low temperatures, or even supercritical dihydrogen-helium mixt