Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Matthew A. Brooke"'
Autor:
Paola Arcidiacono, Catherine M. Webb, Matthew A. Brooke, Huiqing Zhou, Paul J. Delaney, Keat-Eng Ng, Diana C. Blaydon, Andrew Tinker, David P. Kelsell, Anissa Chikh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Mutations in the gene encoding iRHOM2 are associated with hyperproliferative epidermal disorders. Here, the authors show that iRHOM2 is a target gene of p63, that together they regulate inflammation, cell survival and response to oxidative stress, an
Externí odkaz:
https://doaj.org/article/c3aea6eca2d04247a2f4d1f9bed1b658
Autor:
Thiviyani Maruthappu, Anissa Chikh, Benjamin Fell, Paul J. Delaney, Matthew A. Brooke, Clemence Levet, Angela Moncada-Pazos, Akemi Ishida-Yamamoto, Diana Blaydon, Ahmad Waseem, Irene M. Leigh, Matthew Freeman, David P. Kelsell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Keratin 16 is an epithelial protein highly expressed at pressure bearing sites and during wound healing and cancer. Here the authors show that K16 interacts with the inactive protease Rhbdf2, associated with Tylosis with oesophageal cancer, and that
Externí odkaz:
https://doaj.org/article/b4cfedfe8b0b4b1e98605a9262df868a
Autor:
Matthew J. Brooke, John Stenger, Andrej W. Svyantek, Collin Auwarter, Harlene Hatterman-Valenti
Publikováno v:
Weed Technology. 36:15-20
Field trials were conducted to determine the effects of glyphosate and/or dicamba simulated drift rates on chipping potatoes (Solanum tuberosum L.) ‘Atlantic’ and ‘Dakota Pearl.’ Sublethal herbicide rates were applied at the tuber initiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf2d4bc43258a91149ce5c6291fe85f
https://doi.org/10.1017/wet.2021.83
https://doi.org/10.1017/wet.2021.83
Autor:
Pier D. Lambiase, Hari Tandri, Angeliki Asimaki, Matthew A. Brooke, Domenico Corrado, J. Peter van Tintelen, Adalena Tsatsopoulou, William J. McKenna, Hugh Calkins, Jeffrey E. Saffitz, Petros Syrris, Gaetano Thiene, Kalliopi Pilichou, Perry M. Elliott, Alexandros Protonotarios, Barbara Bauce, Firat Duru, Kathleen J. Green, Anneline S.J.M. te Riele, Cristina Basso, Daniel P. Judge, David P. Kelsell, Aris Anastasakis
Publikováno v:
European journal of heart failure, 21(8), 955-964. Wiley-Blackwell
It is 35 years since the first description of arrhythmogenic right ventricular cardiomyopathy (ARVC) and more than 20 years since the first reports establishing desmosomal gene mutations as a major cause of the disease. Early advances in the understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690e70e388b0555e4d0f7f5fe4f9067b
Publikováno v:
Scientific Reports
The vitally important skin barrier is formed by extensive cross-linking activity of transglutaminases (TGs) during terminal epidermal differentiation. We have previously shown that epidermal deficiency of a disintegrin and metalloproteinase 17 (ADAM1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7055b47acce7df4f6844788d78b5d609
http://europepmc.org/articles/PMC5253692
http://europepmc.org/articles/PMC5253692
Publikováno v:
Scientific Reports
The vitally important skin barrier is formed by extensive cross-linking activity of transglutaminases (TGs) during terminal epidermal differentiation. We have previously shown that epidermal deficiency of a disintegrin and metalloproteinase 17 (ADAM1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80954af7e823dd26c34f863b91bdd71c
Autor:
Nicholas S. Kirkby, Franz Rüschendorf, Matthew A. Brooke, Hilary Longhurst, David P. Kelsell, Vincent Plagnol, Thomas T. MacDonald, Jane A. Mitchell, Timothy D. Warner
Publikováno v:
Gut. 63:96-104
Objective Cryptogenic multifocal ulcerating stenosing enteritis (CMUSE) is an extremely rare, but devastating, disease of unknown aetiology. We investigated the genetic basis of this autosomal recessive condition in a pair of affected siblings who ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a443d44b5feb48280629229759794867
https://doi.org/10.1136/gutjnl-2012-303581
https://doi.org/10.1136/gutjnl-2012-303581
Autor:
Thiviyani, Maruthappu, Anissa, Chikh, Benjamin, Fell, Paul J, Delaney, Matthew A, Brooke, Clemence, Levet, Angela, Moncada-Pazos, Akemi, Ishida-Yamamoto, Diana, Blaydon, Ahmad, Waseem, Irene M, Leigh, Matthew, Freeman, David P, Kelsell
Publikováno v:
Nature Communications
Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pressure-bearing sites of the mammalian footpad. It can be induced in hyperproliferative states such as wound healing, inflammation and cancer. Here we show that the inactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77449eee7599565d2f3eca3a4dfc2f1e
https://pubmed.ncbi.nlm.nih.gov/28128203
https://pubmed.ncbi.nlm.nih.gov/28128203
Publikováno v:
Journal of Investigative Dermatology. 134:2486-2488
Dermatologists are frequently asked to see patients with pustular eruptions caused by EGFR mAbs or tyrosine kinase inhibitors. In this issue, Campbell et al. describe an infant with severely inflammed skin and bowel and lung disease caused by a homoz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88998a257860edd2f242989a9d3cf194
https://doi.org/10.1038/jid.2014.228
https://doi.org/10.1038/jid.2014.228
Publikováno v:
Journal of Investigative Dermatology. 138:S133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3eb3fa603ed8071fce03568afa13369
https://doi.org/10.1016/j.jid.2018.03.794
https://doi.org/10.1016/j.jid.2018.03.794