Association of Cardiac Arrest With Opioid Overdose in Transport

Autor: Marissa L Ritter, Adam D Bohr, Matthew B McQueen

Publikováno v: Substance Abuse: Research and Treatment, Vol 16 (2022)

Introduction: Drug overdose is the leading cause of injury-related death in the United States. It has been linked to respiratory depression and cardiac toxicity, both of which can lead to cardiac arrest. Despite this potential association, few studie

Externí odkaz: https://doaj.org/article/bfd773d0964e4d5bb8c154dc6ad78c24

Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers

Autor: Qing Yang, Nicholas R Meyerson, Stephen K Clark, Camille L Paige, Will T Fattor, Alison R Gilchrist, Arturo Barbachano-Guerrero, Benjamin G Healy, Emma R Worden-Sapper, Sharon S Wu, Denise Muhlrad, Carolyn J Decker, Tassa K Saldi, Erika Lasda, Patrick Gonzales, Morgan R Fink, Kimngan L Tat, Cole R Hager, Jack C Davis, Christopher D Ozeroff, Gloria R Brisson, Matthew B McQueen, Leslie A Leinwand, Roy Parker, Sara L Sawyer

Publikováno v: eLife, Vol 10 (2021)

Here, we develop a simple molecular test for SARS-CoV-2 in saliva based on reverse transcription loop-mediated isothermal amplification. The test has two steps: (1) heat saliva with a stabilization solution and (2) detect virus by incubating with a p

Externí odkaz: https://doaj.org/article/d52bb77200174523b04c7043a7af4511

Genetic influences on the human oral microbiome

Autor: Brittany A. Demmitt, Robin P. Corley, Brooke M. Huibregtse, Matthew C. Keller, John K. Hewitt, Matthew B. McQueen, Rob Knight, Ivy McDermott, Kenneth S. Krauter

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)

Abstract Background The human oral microbiome is formed early in development. Its composition is influenced by environmental factors including diet, substance use, oral health, and overall health and disease. The influence of human genes on the compo

Externí odkaz: https://doaj.org/article/b355048dbe4a4478a0f6b555ab4d909d

Effects of routine early treatment with PCSK9 inhibitors in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a randomised, double-blind, sham-controlled trial

Autor: Shamir R. Mehta, Guillaume Pare, Eva M. Lonn, Sanjit S. Jolly, Madhu K. Natarajan, Natalia Pinilla-Echeverri, Jon-David Schwalm, Tej N. Sheth, Matthew Sibbald, Michael Tsang, Nicholas Valettas, James L. Velianou, Shun Fu Lee, Tahsin Ferdous, Sadia Nauman, Helen Nguyen, Tara McCready, Matthew J. McQueen

Publikováno v: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 18(11)

In patients with ST-segment elevation myocardial infarction (STEMI), early initiation of high-intensity statin therapy, regardless of low-density lipoprotein (LDL) cholesterol levels, is the standard of practice worldwide. Aims: We sought to determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ec69a9d20c330684f0b717acb180a2
https://pubmed.ncbi.nlm.nih.gov/36349701

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Autor: Emma C Johnson, Ditte Demontis, Thorgeir E Thorgeirsson, Raymond K Walters, Renato Polimanti, Alexander S Hatoum, Sandra Sanchez-Roige, Sarah E Paul, Frank R Wendt, Toni-Kim Clarke, Dongbing Lai, Gunnar W Reginsson, Hang Zhou, June He, David A A Baranger, Daniel F Gudbjartsson, Robbee Wedow, Daniel E Adkins, Amy E Adkins, Jeffry Alexander, Silviu-Alin Bacanu, Tim B Bigdeli, Joseph Boden, Sandra A Brown, Kathleen K Bucholz, Jonas Bybjerg-Grauholm, Robin P Corley, Louisa Degenhardt, Danielle M Dick, Benjamin W Domingue, Louis Fox, Alison M Goate, Scott D Gordon, Laura M Hack, Dana B Hancock, Sarah M Hartz, Ian B Hickie, David M Hougaard, Kenneth Krauter, Penelope A Lind, Jeanette N McClintick, Matthew B McQueen, Jacquelyn L Meyers, Grant W Montgomery, Ole Mors, Preben B Mortensen, Merete Nordentoft, John F Pearson, Roseann E Peterson, Maureen D Reynolds, John P Rice, Valgerdur Runarsdottir, Nancy L Saccone, Richard Sherva, Judy L Silberg, Ralph E Tarter, Thorarinn Tyrfingsson, Tamara L Wall, Bradley T Webb, Thomas Werge, Leah Wetherill, Margaret J Wright, Stephanie Zellers, Mark J Adams, Laura J Bierut, Jason D Boardman, William E Copeland, Lindsay A Farrer, Tatiana M Foroud, Nathan A Gillespie, Richard A Grucza, Kathleen Mullan Harris, Andrew C Heath, Victor Hesselbrock, John K Hewitt, Christian J Hopfer, John Horwood, William G Iacono, Eric O Johnson, Kenneth S Kendler, Martin A Kennedy, Henry R Kranzler, Pamela A F Madden, Hermine H Maes, Brion S Maher, Nicholas G Martin, Matthew McGue, Andrew M McIntosh, Sarah E Medland, Elliot C Nelson, Bernice Porjesz, Brien P Riley, Michael C Stallings, Michael M Vanyukov, Scott Vrieze, Lea K Davis, Ryan Bogdan, Joel Gelernter, Howard J Edenberg, Kari Stefansson, Anders D Børglum, Arpana Agrawal, Raymond Walters, Emma Johnson, Jeanette McClintick, Alexander Hatoum, Frank Wendt, Mark Adams, Amy Adkins, Fazil Aliev, Anthony Batzler, Sarah Bertelsen, Joanna Biernacka, Tim Bigdeli, Li-Shiun Chen, Yi-Ling Chou, Franziska Degenhardt, Anna Docherty, Alexis Edwards, Pierre Fontanillas, Jerome Foo, Josef Frank, Ina Giegling, Scott Gordon, Laura Hack, Annette Hartmann, Sarah Hartz, Stefanie Heilmann-Heimbach, Stefan Herms, Colin Hodgkinson, Per Hoffman, Jouke Hottenga, Martin Kennedy, Mervi Alanne-Kinnunen, Bettina Konte, Jari Lahti, Marius Lahti-Pulkkinen, Lannie Ligthart, Anu Loukola, Brion Maher, Hamdi Mbarek, Andrew McIntosh, Matthew McQueen, Jacquelyn Meyers, Yuri Milaneschi, Teemu Palviainen, John Pearson, Roseann Peterson, Samuli Ripatti, Euijung Ryu, Nancy Saccone, Jessica Salvatore, Melanie Schwandt, Fabian Streit, Jana Strohmaier, Nathaniel Thomas, Jen-Chyong Wang, Bradley Webb, Amanda Wills, Jason Boardman, Danfeng Chen, Doo-Sup Choi, William Copeland, Robert Culverhouse, Norbert Dahmen, Benjamin Domingue, Sarah Elson, Mark Frye, Wolfgang Gäbel, Caroline Hayward, Marcus Ising, Margaret Keyes, Falk Kiefer, John Kramer, Samuel Kuperman, Susanne Lucae, Michael Lynskey, Wolfgang Maier, Karl Mann, Satu Männistö, Bertram Müller-Myhsok, Alison Murray, John Nurnberger, Aarno Palotie, Ulrich Preuss, Katri Räikkönen, Maureen Reynolds, Monika Ridinger, Norbert Scherbaum, Marc Schuckit, Michael Soyka, Jens Treutlein, Stephanie Witt, Norbert Wodarz, Peter Zill, Daniel Adkins, Dorret Boomsma, Laura Bierut, Sandra Brown, Kathleen Bucholz, Sven Cichon, E. Jane Costello, Harriet de Wit, Nancy Diazgranados, Danielle Dick, Johan Eriksson, Lindsay Farrer, Tatiana Foroud, Nathan Gillespie, Alison Goate, David Goldman, Richard Grucza, Dana Hancock, Andrew Heath, John Hewitt, Christian Hopfer, William Iacono, Eric Johnson, Jaakko Kaprio, Victor Karpyak, Kenneth Kendler, Henry Kranzler, Paul Lichtenstein, Penelope Lind, Matt McGue, James MacKillop, Pamela Madden, Hermine Maes, Patrik Magnusson, Nicholas Martin, Sarah Medland, Grant Montgomery, Elliot Nelson, Markus Nöthen, Abraham Palmer, Nancy Pederson, Brenda Penninx, John Rice, Marcella Rietschel, Brien Riley, Richard Rose, Dan Rujescu, Pei-Hong Shen, Judy Silberg, Michael Stallings, Ralph Tarter, Michael Vanyukov, Tamara Wall, John Whitfield, Hongyu Zhao, Benjamin Neale, Howard Edenberg

Publikováno v: Johnson, E, Hottenga, J, Ligthart, L, Mbarek, H, Milaneschi, Y, Boomsma, D, Agrawal, A & Psychiatric Genomics Consortium Substance Use Disorders Workgroup 2020, ' A large-scale genome-wide association study meta-analysis of cannabis use disorder ', The Lancet Psychiatry, vol. 7, no. 12, pp. 1032-1045 . https://doi.org/10.1016/S2215-0366(20)30339-4
Johnson, E C, Demontis, D, Thorgeirsson, T E, Walters, R K, Polimanti, R, Hatoum, A S, Sanchez-Roige, S, Paul, S E, Wendt, F R, Clarke, T-K, Lai, D, Reginsson, G W, Zhou, H, He, J, Baranger, D A A, Gudbjartsson, D F, Wedow, R, Adkins, D E, Adkins, A E, Alexander, J, Bacanu, S-A, Bigdeli, T B, Boden, J, Brown, S A, Bucholz, K K, Bybjerg-Grauholm, J, Corley, R P, Degenhardt, L, Dick, D M, Domingue, B W, Fox, L, Goate, A M, Gordon, S D, Hack, L M, Hancock, D B, Hartz, S M, Hickie, I B, Hougaard, D M, Krauter, K, Lind, P A, McClintick, J N, McQueen, M B, Meyers, J L, Montgomery, G W, Mors, O, Mortensen, P B, Nordentoft, M, Pearson, J F, Peterson, R E, Børglum, A D & Psychiatric Genomics Consortium Substance Use Disorders Workgroup 2020, ' A large-scale genome-wide association study meta-analysis of cannabis use disorder ', The Lancet Psychiatry, vol. 7, no. 12, pp. 1032-1045 . https://doi.org/10.1016/S2215-0366(20)30339-4
The Lancet Psychiatry, 7(12), 1032-1045. Elsevier Limited
The Lancet. Psychiatry
Johnson, E C, Demontis, D, Thorgeirsson, T E, Walters, R, Polimanti, R, Hatoum, A S, Sanchez-roige, S, Paul, S E, Wendt, F R, Clarke, T, Lai, D, Reginsson, G W, Zhou, H, He, J, Baranger, D A A, Gudbjartsson, D F, Wedow, R, Adkins, D, Adkins, A, Alexander, J, Bacanu, S, Bigdeli, T B, Boden, J, Brown, S A, Bucholz, K, Bybjerg-grauholm, J, Corley, R P, Degenhardt, L, Dick, D, Domingue, B, Fox, L, Goate, A M, Gordon, S, Hack, L, Hancock, D, Hartz, S, Hickie, I B, Hougaard, D M, Krauter, K, Lind, P, Mcclintick, J, Mcqueen, M, Meyers, J, Montgomery, G, Mors, O, Mortensen, P B, Nordentoft, M, Pearson, J F, Peterson, R, Reynolds, M, Rice, J, Runarsdottir, V, Saccone, N, Sherva, R, Silberg, J L, Tarter, R, Tyrfingsson, T, Wall, T, Webb, B, Werge, T, Wetherill, L, Wright, M J, Zellers, S, Adams, M J, Bierut, L, Boardman, J, Copeland, W, Farrer, L, Foroud, T M, Gillespie, N A, Grucza, R A, Harris, K M, Heath, A, Hesselbrock, V, Hewitt, J, Hopfer, C, Horwood, J, Iacono, W G, Johnson, E, Kendler, K, Kennedy, M, Kranzler, H, Madden, P A F, Maes, H, Maher, B, Martin, N G, Mcgue, M, Mcintosh, A M, Medland, S, Nelson, E C, Porjesz, B, Riley, B, Stallings, M, Vanyukov, M, Vrieze, S, Davis, L K, Bogdan, R, Gelernter, J, Edenberg, H, Stefansson, K, Børglum, A D, Agrawal, A, Walters, R, Polimanti, R, Johnson, E, Mcclintick, J, Hatoum, A, He, J, Wendt, F, Zhou, H, Adkins, A, Aliev, F, Bacanu, S, Batzler, A, Bertelsen, S, Biernacka, J, Bigdeli, T, Chen, L, Clarke, T, Chou, Y, Degenhardt, F, Docherty, A, Edwards, A, Fontanillas, P, Foo, J, Fox, L, Frank, J, Giegling, I, Gordon, S, Hack, L, Hartmann, A, Hartz, S, Heilmann-heimbach, S, Herms, S, Hodgkinson, C, Hoffman, P, Hottenga, J, Kennedy, M, Alanne-kinnunen, M, Konte, B, Lahti, J, Lahti-pulkkinen, M, Lai, D, Ligthart, L, Loukola, A, Maher, B, Mbarek, H, Mcintosh, A M, Mcqueen, M, Meyers, J, Milaneschi, Y, Palviainen, T, Pearson, J, Peterson, R, Ripatti, S, Ryu, E, Saccone, N, Salvatore, J, Sanchez-roige, S, Schwandt, M, Sherva, R, Streit, F, Strohmaier, J, Thomas, N, Wang, J, Webb, B, Wedow, R, Wetherill, L, Wills, A, Boardman, J, Chen, D, Choi, D, Copeland, W, Culverhouse, R, Dahmen, N, Degenhardt, L, Domingue, B, Elson, S, Frye, M, Gäbel, W, Hayward, C, Ising, M, Keyes, M, Kiefer, F, Kramer, J, Kuperman, S, Lucae, S, Lynskey, M, Maier, W, Mann, K, Männistö, S, Müller-myhsok, B, Murray, A, Nurnberger, J, Palotie, A, Preuss, U, Räikkönen, K, Reynolds, M, Ridinger, M, Scherbaum, N, Schuckit, M, Soyka, M, Treutlein, J, Witt, S, Wodarz, N, Zill, P, Adkins, D, Boden, J, Boomsma, D, Bierut, L, Brown, S, Bucholz, K, Cichon, S, Costello, E J, De Wit, H, Diazgranados, N, Dick, D, Eriksson, J, Farrer, L, Foroud, T, Gillespie, N, Goate, A, Goldman, D, Grucza, R, Hancock, D, Harris, K M, Heath, A, Hesselbrock, V, Hewitt, J, Hopfer, C, Horwood, J, Iacono, W, Johnson, E, Kaprio, J, Karpyak, V, Kendler, K, Kranzler, H, Krauter, K, Lichtenstein, P, Lind, P, Mcgue, M, Mackillop, J, Madden, P, Maes, H, Magnusson, P, Martin, N, Medland, S, Montgomery, G, Nelson, E, Nöthen, M, Palmer, A, Pederson, N, Penninx, B, Porjesz, B, Rice, J, Rietschel, M, Riley, B, Rose, R, Rujescu, D, Shen, P, Silberg, J, Stallings, M, Tarter, R, Vanyukov, M, Vrieze, S, Wall, T, Whitfield, J, Zhao, H, Neale, B, Gelernter, J, Edenberg, H & Agrawal, A 2020, ' A large-scale genome-wide association study meta-analysis of cannabis use disorder ', The Lancet Psychiatry, vol. 7, no. 12, pp. 1032-1045 . https://doi.org/10.1016/S2215-0366(20)30339-4
Johnson, E C, Demontis, D, Thorgeirsson, T E, Walters, R K, Polimanti, R, Hatoum, A S, Sanchez-Roige, S, Paul, S E, Wendt, F R, Clarke, T K, Lai, D, Reginsson, G W, Zhou, H, He, J, Baranger, D A A, Gudbjartsson, D F, Wedow, R, Adkins, D E, Adkins, A E, Alexander, J, Bacanu, S A, Bigdeli, T B, Boden, J, Brown, S A, Bucholz, K K, Bybjerg-Grauholm, J, Corley, R P, Degenhardt, L, Dick, D M, Domingue, B W, Fox, L, Goate, A M, Gordon, S D, Hack, L M, Hancock, D B, Hartz, S M, Hickie, I B, Hougaard, D M, Krauter, K, Lind, P A, McClintick, J N, McQueen, M B, Meyers, J L, Montgomery, G W, Mors, O, Mortensen, P B, Nordentoft, M, Pearson, J F, Peterson, R E, Werge, T & Psychiatric Genomics Consortium Substance Use Disorders Workgroup 2020, ' A large-scale genome-wide association study meta-analysis of cannabis use disorder ', The Lancet Psychiatry, vol. 7, no. 12, pp. 1032-1045 . https://doi.org/10.1016/S2215-0366(20)30339-4
Psychiatric Genomics Consortium Substance Use Disorders Workgroup 2020, ' A large-scale genome-wide association study meta-analysis of cannabis use disorder ', The Lancet Psychiatry, vol. 7, no. 12, pp. 1032-1045 . https://doi.org/10.1016/S2215-0366(20)30339-4
The Lancet Psychiatry

Background: Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50–70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e1394595d95a3f48eb1610651d6d82
https://doi.org/10.1016/s2215-0366(20)30339-4