Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Matthew A Ingersoll"'
Autor:
Matthew A Ingersoll, Anastesia S Lyons, Sakthivel Muniyan, Napoleon D'Cunha, Tashika Robinson, Kyle Hoelting, Jennifer G Dwyer, Xiu R Bu, Surinder K Batra, Ming-Fong Lin
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131811 (2015)
Prostate cancer (PCa) is the second leading cause of cancer-related death afflicting United States males. Most treatments to-date for metastatic PCa include androgen-deprivation therapy and second-generation anti-androgens such as abiraterone acetate
Externí odkaz:
https://doaj.org/article/bf1d11e02f414ed0a045e6b410e949ed
Autor:
Emma J. Sailor‐Longsworth, Richard D. Lutze, Matthew A. Ingersoll, Regina G. Kelmann, Kristina Ly, Duane Currier, Taosheng Chen, Jian Zuo, Tal Teitz
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/564517f49b474da09fde9f7eb22d8098
Autor:
Richard D. Lutze, Matthew A. Ingersoll, Alena Thotam, Anjali Joseph, Joshua Fernandes, Tal Teitz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6305 (2024)
Noise-induced hearing loss (NIHL) is a major cause of hearing impairment and is linked to dementia and mental health conditions, yet no FDA-approved drugs exist to prevent it. Downregulating the mitogen-activated protein kinase (MAPK) cellular pathwa
Externí odkaz:
https://doaj.org/article/a3e7605dc009459e9228bbad5ebdbefb
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 735 (2024)
Hearing loss is one of the most common types of disability; however, there is only one FDA-approved drug to prevent any type of hearing loss. Treatment with the highly effective chemotherapy agent, cisplatin, and exposure to high-decibel noises are t
Externí odkaz:
https://doaj.org/article/2592530a25294166b176c7ca5ee642a6
Autor:
Dannah R, Miller, Matthew A, Ingersoll, Yu-Wei, Chou, Elizabeth A, Kosmacek, Rebecca E, Oberley-Deegan, Ming-Fong, Lin
Publikováno v:
Free Radical Biology and Medicine. 193:274-291
The castration-resistant (CR) prostate cancer (PCa) is lethal and is the second leading cause of cancer-related deaths in U.S. males. To develop effective treatments toward CR PCa, we investigated reactive oxygen species (ROS) signaling pathway for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e104fc921fae40424f3baecae3a822e6
https://doi.org/10.1016/j.freeradbiomed.2022.10.269
https://doi.org/10.1016/j.freeradbiomed.2022.10.269
Publikováno v:
Prostate Cancer ISBN: 9780645001754
Prostate cancer is the most commonly diagnosed solid tumor and the second leading cause of cancer-related deaths in men in the United States. While localized prostate cancer has an excellent prognosis for patients, about one-third of patients are dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437e77bb959a2975bbd14b088177eacf
https://doi.org/10.36255/exonpublications.prostatecancer.combinationtreatment.2021
https://doi.org/10.36255/exonpublications.prostatecancer.combinationtreatment.2021
Publikováno v:
Am J Clin Exp Urol
Prostate cancer (PCa) is the most commonly diagnosed solid tumor and the second leading cause of cancer-related deaths in U.S. men in 2020. Androgen-deprivation therapy (ADT) is the standard of care for metastatic PCa. Unfortunately, PCa relapse ofte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d30f7eced877421d671dda35e6e69cc
https://pubmed.ncbi.nlm.nih.gov/33816699
https://pubmed.ncbi.nlm.nih.gov/33816699
Autor:
Huizhan Liu, Lauryn E. Caster, Marisa Zallocchi, Jian Zuo, Zhenhang Xu, Jaeki Min, Eva M. Holland, David Z.Z. He, Matthew A. Ingersoll, Duane G. Currier, Tal Teitz, Taosheng Chen, Emma A. Malloy
Publikováno v:
Science Advances
Dabrafenib, an FDA-approved oral anticancer drug, prevents cisplatin- and noise-induced hearing loss in animal models.
Hearing loss caused by noise, aging, antibiotics, and chemotherapy affects 10% of the world population, yet there are no Food
Hearing loss caused by noise, aging, antibiotics, and chemotherapy affects 10% of the world population, yet there are no Food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ab8e409e01b62a49ccb2d385b02cf2
https://pubmed.ncbi.nlm.nih.gov/33268358
https://pubmed.ncbi.nlm.nih.gov/33268358
Autor:
Matthew A. Ingersoll, Dannah R. Miller, Ming Fong Lin, C. Brent Wakefield, October Martinez, M. Vijaya Simha, Chai-Lin Kao, Surinder K. Batra, Kuan Chan Hsieh, Hui Ting Chen
Publikováno v:
Cancer Letters. 383:94-105
Despite recent advances in modern medicine, castration-resistant prostate cancer remains an incurable disease. Subpopulations of prostate cancer cells develop castration-resistance by obtaining the complete steroidogenic ability to synthesize androge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d1c0da76ee5671ddd63807418ad040
https://doi.org/10.1016/j.canlet.2016.09.008
https://doi.org/10.1016/j.canlet.2016.09.008