Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Matthew A Edwardson"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract We sought to identify alterations in the quantity of plasma brain-derived extracellular vesicles (EV) over the first month post-stroke to shed light on related injury and repair mechanisms. We assessed plasma levels of presumed neuron-derive
Externí odkaz:
https://doaj.org/article/10caa4ab37844273b1ad4814bb3673cf
Autor:
Matthew A. Edwardson
Publikováno v:
Medical Education Online, Vol 26, Iss 1 (2021)
Despite many advances in medical education, medical students continue to mostly shadow on inpatient rotations like Neurology. They seldom receive face-to-face feedback or mentorship from attending physicians. This results from not training attending
Externí odkaz:
https://doaj.org/article/099a71eb886240409e145d3eb27cd298
Autor:
Matthew A. Edwardson, Kathaleen Brady, Margot L. Giannetti, Shashwati Geed, Jessica Barth, Abigail Mitchell, Ming T. Tan, Yizhao Zhou, Barbara S. Bregman, Elissa L. Newport, Dorothy F. Edwards, Alexander W. Dromerick
Publikováno v:
Neurorehabilitation and Neural Repair. 37:76-79
The Critical Periods After Stroke Study (CPASS, n = 72) showed that, compared to controls, an additional 20 hours of intensive upper limb therapy led to variable gains on the Action Research Arm Test depending on when therapy was started post-stroke:
Autor:
Matthew A. Edwardson, Xiaogang Zhong, Massimo S. Fiandaca, Howard J. Federoff, Amrita K. Cheema, Alexander W. Dromerick
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Preclinical investigators have implicated several microRNAs as regulators of gene expression promoting neural plasticity following experimental stroke in rodent models. Our goal was to determine whether similar microRNAs might be identifiabl
Externí odkaz:
https://doaj.org/article/9f847088b66f4bda936c58861b0c0ecd
Autor:
Matthew A. Edwardson, Li Ding, Caron Park, Christianne J. Lane, Monica A. Nelsen, Steven L. Wolf, Carolee J. Winstein, Alexander W. Dromerick
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background: Research imaging costs limit lesion-based analyses in already expensive large stroke rehabilitation trials. Despite the belief that lesion characteristics influence recovery and treatment response, prior studies have not sufficiently addr
Externí odkaz:
https://doaj.org/article/54e24b189b16469e8fa4079c1566dbff
Autor:
Matthew A Edwardson, Narayan Shivapurkar, Xin Li, Muhib Khan, Jamal Smith, Margot L Giannetti, Ruzong Fan, Alexander W Dromerick
Publikováno v:
Stroke. 54
Introduction: Stroke induces changes in plasma microRNA (miRNA) expression in the first 24hrs post-injury, but few have characterized miRNA expression during the early recovery phase. Hypothesis: We hypothesized that plasma miRNA expression would evo
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 35-36 (2019)
OBJECTIVES/SPECIFIC AIMS: There are currently no established blood-based biomarkers of recovery and neural repair following stroke in humans. Such biomarkers would be extremely valuable for aiding in stroke prognosis, timing rehabilitation therapies,
Externí odkaz:
https://doaj.org/article/71bb2e75ce434be8b80821fd4d2ed814
Autor:
Sunbin Song, Reinoud P H Bokkers, Marie Luby, Matthew A Edwardson, Tyler Brown, Shreyansh Shah, Robert W Cox, Ziad S Saad, Richard C Reynolds, Daniel R Glen, Leonardo G Cohen, Lawrence L Latour
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185552 (2017)
Interpretation of the extent of perfusion deficits in stroke MRI is highly dependent on the method used for analyzing the perfusion-weighted signal intensity time-series after gadolinium injection. In this study, we introduce a new model-free standar
Externí odkaz:
https://doaj.org/article/fddb2dc418a840e1842c4e03d7d99910
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 45-45 (2018)
OBJECTIVES/SPECIFIC AIMS: MicroRNAs are small, non-coding RNAs that control gene expression by inhibiting protein translation. Preclinical studies in rodent stroke models suggest that changes in microRNA expression contribute to neural repair mechani
Externí odkaz:
https://doaj.org/article/f5ae531f61434d85a351bf246a1dc5c9
Autor:
Alexander W Dromerick, Matthew A Edwardson, Dorothy F Edwards, Margot L Giannetti, Jessica eBarth, Kathaleen P Brady, Evan eChan, Ming T Tan, Irfan eTamboli, Ruth eChia, Michael eOrquiza, Robert M Padilla, Amrita K Cheema, Mark E Mapstone, Massimo S Fiandaca, Howard J Federoff, Elissa L Newport
Publikováno v:
Frontiers in Human Neuroscience, Vol 9 (2015)
Introduction: 795,000 Americans will have a stroke this year, and half will have a chronic hemiparesis. Substantial animal literature suggests that the mammalian brain has much potential to recover from acute injury using mechanisms of neuroplasticit
Externí odkaz:
https://doaj.org/article/756114495a934f7094d63c0edf56a88c