Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Matthew A Ciorba"'
Autor:
Ellen Li, Yuanhao Zhang, Xinyu Tian, Xuefeng Wang, Grace Gathungu, Ashley Wolber, Shehzad S Shiekh, R Balfour Sartor, Nicholas O Davidson, Matthew A Ciorba, Wei Zhu, Leah M Nelson, Charles E Robertson, Daniel N Frank
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213108 (2019)
We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome ("dysbiosis") in a patient cohort. Here we report an integrative analysis of an expanded number of Crohn's
Externí odkaz:
https://doaj.org/article/ad3762b0d92d4bcf81d74fefb6118511
Autor:
Alaullah Sheikh, Rasheduzzaman Rashu, Yasmin Ara Begum, F Matthew Kuhlman, Matthew A Ciorba, Scott J Hultgren, Firdausi Qadri, James M Fleckenstein
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005586 (2017)
Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries. Efficient delivery of these toxins requires ETEC to engag
Externí odkaz:
https://doaj.org/article/20b9e7b27bac471fa50a59257d2aee30
Autor:
Lori R. Holtz, B. Darren Nix, Sewuese E. Akuse, Carla Hall-Moore, Rodney D. Newberry, Matthew A. Ciorba, Parakkal Deepak, Maria Zulfiqar, Jeng-Jong Shieh, James R. Johnson, I. Rochelle Riley, Richard B. Dorshow
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 4, Pp 491-497 (2024)
Background and Aims: The dual sugar absorption test as a classic measure of human intestinal permeability has limited clinical utility due to lengthy and cumbersome urine collection, assay variability, and long turnaround. We aimed to determine if th
Externí odkaz:
https://doaj.org/article/032a99dca9c1478a80c46ccf9302f4f5
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133098 (2015)
Externí odkaz:
https://doaj.org/article/9ee08f1e0e004e8faa71f569abb76794
Autor:
Nancy D. Marin, Michelle Becker-Hapak, Wilbur M. Song, Quazim A. Alayo, Lynne Marsala, Naomi Sonnek, Melissa M. Berrien-Elliott, Mark Foster, Jennifer A. Foltz, Jennifer Tran, Pamela Wong, Celia C. Cubitt, Patrick Pence, Kimberly Hwang, Alice Y. Zhou, Miriam T. Jacobs, Timothy Schappe, David A. Russler-Germain, Ryan C. Fields, Matthew A. Ciorba, Todd A. Fehniger
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMetastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient (dMMR)/microsatellit
Externí odkaz:
https://doaj.org/article/989a296ad9bc48bf902f4f5ef1d3f555
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115848 (2014)
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Genetic polymorphisms can confer CD risk and influence disease phenotype. Indoleamine 2,3 dioxygenase-1 (IDO1) is one of the most over-expressed genes in CD and med
Externí odkaz:
https://doaj.org/article/302b8e9617db486eaa9402b1dd2f49c4
Autor:
Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B. Kutluay, Matthew A. Ciorba, Siyuan Ding
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has been dedicated to identifying effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of calpain inhibitors
Externí odkaz:
https://doaj.org/article/ea4945db2bf6456cb0f9f479f9a0b715
Autor:
Avan Antia, David M. Alvarado, Qiru Zeng, Luis A. Casorla-Perez, Deanna L. Davis, Naomi M. Sonnek, Matthew A. Ciorba, Siyuan Ding
Publikováno v:
Viruses, Vol 16, Iss 4, p 634 (2024)
The Omicron variant of SARS-CoV-2, characterized by multiple subvariants including BA.1, XBB.1.5, EG.5, and JN.1, became the predominant strain in early 2022. Studies indicate that Omicron replicates less efficiently in lung tissue compared to the an
Externí odkaz:
https://doaj.org/article/38974c74f9894c49aa5e9ae3369a7b50
Autor:
Saeed Soleymanjahi, Valerie Blanc, Elizabeth A. Molitor, David M. Alvarado, Yan Xie, Vered Gazit, Jeffrey W. Brown, Kathleen Byrnes, Ta-Chiang Liu, Jason C. Mills, Matthew A. Ciorba, Deborah C. Rubin, Nicholas O. Davidson
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
RNA-binding protein 47 (RBM47) is required for embryonic endoderm development, but a role in adult intestine is unknown. We studied intestine-specific Rbm47-knockout mice (Rbm47-IKO) following intestinal injury and made crosses into ApcMin/+ mice to
Externí odkaz:
https://doaj.org/article/edc9e8e3efab4366b48b55f69d04abad
Autor:
Monica M. Yang, Kimberly E. Taylor, Diana Paez, Alex Carividi, Emanuel Demissie, Niti Pawar, Alia A. El‐Qunni, Lily E. McMorrow, Rebecca E. Schriefer, Katherine Huang, Baylee Kinnett, Michael Klebert, Alem Haile, Jane A. O'Halloran, Rachel M. Presti, Wooseob Kim, Ali H. Ellebedy, Matthew A. Ciorba, Michael A. Paley, Parakkal Deepak, Alfred H. J. Kim, Patricia Katz, Mehrdad Matloubian, Mary Nakamura, Lianne S. Gensler
Publikováno v:
Arthritis Care & Research. 74:1953-1960
Little is known regarding the reactogenicity and related SARS-CoV-2 vaccine response in patients with chronic inflammatory disease (CID). Our objective was to characterize the adverse event profile of CID patients following SARS-CoV-2 vaccination and