Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Matthew A Child"'
Autor:
Megan Garland, Christopher J Schulze, Ian T Foe, Wouter A van der Linden, Matthew A Child, Matthew Bogyo
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190255 (2018)
Protein palmitoylation is a dynamic post-translational modification (PTM) important for cellular functions such as protein stability, trafficking, localization, and protein-protein interactions. S-palmitoylation occurs via the addition of palmitate t
Externí odkaz:
https://doaj.org/article/e5d8492e87b545fe8500288befcbf7ae
Autor:
Moritz Treeck, John L Sanders, Rajshekhar Y Gaji, Kacie A LaFavers, Matthew A Child, Gustavo Arrizabalaga, Joshua E Elias, John C Boothroyd
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004197 (2014)
Calcium-dependent protein kinases (CDPKs) are conserved in plants and apicomplexan parasites. In Toxoplasma gondii, TgCDPK3 regulates parasite egress from the host cell in the presence of a calcium-ionophore. The targets and the pathways that the kin
Externí odkaz:
https://doaj.org/article/524d9946ca3f4389accbbde822d34a7b
Publikováno v:
Conservation Science and Practice, Vol 6, Iss 7, Pp n/a-n/a (2024)
Abstract The expansion of wildlife ranching has been broadly linked to conservation benefits, job creation, and economic contributions. However, a more nuanced understanding of the socioeconomic contributions of wildlife ranching accounting for the e
Externí odkaz:
https://doaj.org/article/c9a0d232cad7418e80fe72fbe697de1c
Autor:
Mathieu Nonnenmacher, Wei Wang, Matthew A. Child, Xiao-Qin Ren, Carol Huang, Amy Zhen Ren, Jenna Tocci, Qingmin Chen, Kelsey Bittner, Katherine Tyson, Nilesh Pande, Charlotte Hiu-Yan Chung, Steven M. Paul, Jay Hou
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 366-378 (2021)
Therapeutic payload delivery to the central nervous system (CNS) remains a major challenge in gene therapy. Recent studies using function-driven evolution of adeno-associated virus (AAV) vectors have successfully identified engineered capsids with im
Externí odkaz:
https://doaj.org/article/fa7202f054c14b0abb47979c4151abb9
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 6, Pp 1-7 (2020)
Abstract Rational molecular engineering of proteins with CRISPR‐based approaches is challenged by the gene‐centric nature of gRNA design tools. To address this, we have developed CRISPR‐TAPE, a protein‐centric gRNA design algorithm that allow
Externí odkaz:
https://doaj.org/article/99f8136a3dd34f8bb685d5a240a61272
Autor:
Eduardo Alves, Henry J. Benns, Lilian Magnus, Caia Dominicus, Tamás Dobai, Joshua Blight, Ceire J. Wincott, Matthew A. Child
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The ability of an organism to sense and respond to environmental redox fluctuations relies on a signaling network that is incompletely understood in apicomplexan parasites such as Toxoplasma gondii. The impact of changes in redox upon the development
Externí odkaz:
https://doaj.org/article/cbcc61d597de49f5a8fca131f01f65a0
Autor:
Friederike C. Bolam, Louise Mair, Marco Angelico, Thomas M. Brooks, Mark Burgman, Claudia Hermes, Michael Hoffmann, Rob W. Martin, Philip J.K. McGowan, Ana S.L. Rodrigues, Carlo Rondinini, James R.S. Westrip, Hannah Wheatley, Yuliana Bedolla‐Guzmán, Javier Calzada, Matthew F. Child, Peter A. Cranswick, Christopher R. Dickman, Birgit Fessl, Diana O. Fisher, Stephen T. Garnett, Jim J. Groombridge, Christopher N. Johnson, Rosalind J. Kennerley, Sarah R.B. King, John F. Lamoreux, Alexander C. Lees, Luc Lens, Simon P. Mahood, David P. Mallon, Erik Meijaard, Federico Méndez‐Sánchez, Alexandre Reis Percequillo, Tracey J. Regan, Luis Miguel Renjifo, Malin C. Rivers, Nicolette S. Roach, Lizanne Roxburgh, Roger J. Safford, Paul Salaman, Tom Squires, Ella Vázquez‐Domínguez, Piero Visconti, John C.Z. Woinarski, Richard P. Young, Stuart H.M. Butchart
Publikováno v:
Conservation Letters, Vol 14, Iss 1, Pp n/a-n/a (2021)
Abstract Aichi Target 12 of the Convention on Biological Diversity (CBD) contains the aim to ‘prevent extinctions of known threatened species’. To measure the degree to which this was achieved, we used expert elicitation to estimate the number of
Externí odkaz:
https://doaj.org/article/79d19f1882d8484aac92415452eccd7e
Publikováno v:
Nature Sustainability. 5:1040-1048
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bbcf722dadf55c7e16a6aec8c7acc52
https://doi.org/10.1038/s41893-022-00961-1
https://doi.org/10.1038/s41893-022-00961-1
Autor:
Surendra Kumar, Kolli, Alvaro, Molina-Cruz, Tamasa, Araki, Fiona J A, Geurten, Jai, Ramesar, Severine, Chevalley-Maurel, Hans J, Kroeze, Sascha, Bezemer, Clarize, de Korne, Roxanne, Withers, Nadia, Raytselis, Angela F, El Hebieshy, Robbert Q, Kim, Matthew A, Child, Soichiro, Kakuta, Hajime, Hisaeda, Hirotaka, Kobayashi, Takeshi, Annoura, Paul J, Hensbergen, Blandine M, Franke-Fayard, Carolina, Barillas-Mury, Ferenc A, Scheeren, Chris J, Janse
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
Glutaminyl cyclase (QC) modifies N-terminal glutamine or glutamic acid residues of target proteins into cyclic pyroglutamic acid (pGlu). Here, we report the biochemical and functional analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24b873684a162fb0248f312ec6e217ef
https://pubmed.ncbi.nlm.nih.gov/35994647
https://pubmed.ncbi.nlm.nih.gov/35994647
Autor:
Matthew F. Child, W. Andrew Taylor, Claire Relton, Samantha K. Nicholson, Peter A. Lindsey, Harriet T. Davies-Mostert
Publikováno v:
Biodiversity and Conservation. 30:4111-4135
Reversing biodiversity loss is a global imperative that requires setting aside sufficient space for species. In South Africa, an estimated area of 20 million ha is under wildlife ranching, a form of private land enterprise that adopts wildlife-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2047e65c1cf87492458015618dcf506c
https://doi.org/10.1007/s10531-021-02294-5
https://doi.org/10.1007/s10531-021-02294-5