Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Matthew A Burchill"'
Autor:
Matthew A Burchill, Matthew P Salomon, Lucy Golden-Mason, Amanda Wieland, Ana C Maretti-Mira, Michael Gale, Hugo R Rosen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009799 (2021)
Chronic infection with HCV is manifested by dysregulation of innate immune responses and impaired T cell function at multiple levels. These changes may impact susceptibility to other infections, responsiveness to antiviral therapies, vaccine responsi
Externí odkaz:
https://doaj.org/article/4b3c7cb12eb447ffbe8a00b8895b480b
Autor:
Eric T Clambey, Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Sana D Karam, Michael W Knitz, Ayman J Oweida, Adam C Mueller, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Beth A Jirón Tamburini, Edward D Chan, Curtis R Pickering
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background Numerous trials combining radiation therapy (RT) and immunotherapy in head and neck squamous cell carcinoma (HNSCC) are failing. Using preclinical immune cold models of HNSCC resistant to RT-immune checkpoint inhibitors, we investigate the
Externí odkaz:
https://doaj.org/article/cbf79a9cbfcd4744b19d4b8a1b088264
Autor:
Shannon M Walsh, Ryan M Sheridan, Erin D Lucas, Thu A Doan, Brian C Ware, Johnathon Schafer, Rui Fu, Matthew A Burchill, Jay R Hesselberth, Beth Ann Jiron Tamburini
Publikováno v:
eLife, Vol 10 (2021)
The detection of foreign antigens in vivo has relied on fluorescent conjugation or indirect read-outs such as antigen presentation. In our studies, we found that these widely used techniques had several technical limitations that have precluded a com
Externí odkaz:
https://doaj.org/article/e1a779a5cbfd4b2eb30dfea75847fa35
Autor:
Matthew A Burchill, Justin A Roby, Nanette Crochet, Megan Wind-Rotolo, Amy E Stone, Michael G Edwards, Rachael J Dran, Michael S Kriss, Michael Gale, Hugo R Rosen
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186213 (2017)
ResultsFirst, in patients receiving two different combinations of DAAs, we found that DAAs induced not only rapid viral clearance, but also a re-setting of antiviral immune responses in the peripheral blood. Specifically, we see a rapid decline in th
Externí odkaz:
https://doaj.org/article/66720068face4cb0ad7a33940e4a2f9e
Autor:
Kathryn D. Tuttle, Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael Ludwig, Zdenek Andrysik, Matthew A. Burchill, Beth A.J. Tamburini, Colin Sempeck, Keith Smith, Ross Granrath, Dayna Tracy, Jessica Baxter, Joaquin M. Espinosa, Kelly D. Sullivan
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108407- (2020)
Summary: Individuals with Down syndrome (DS; trisomy 21) display hyperactivation of interferon (IFN) signaling and chronic inflammation, which could potentially be explained by the extra copy of four IFN receptor (IFNR) genes encoded on chromosome 21
Externí odkaz:
https://doaj.org/article/8fd7536ebdba4b9c98e33eeca1e00d4f
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Chronic liver disease (CLD) is a global health epidemic causing ∼2 million deaths annually worldwide. As the incidence of CLD is expected to rise over the next decade, understanding the cellular and molecular mediators of CLD is critical for develo
Externí odkaz:
https://doaj.org/article/7fac8e53a534473cb2ce56de11424bc2
Autor:
Beth A. Jiron Tamburini, Jeffrey M. Finlon, Austin E. Gillen, Michael S. Kriss, Kent A. Riemondy, Rui Fu, Ronald P. Schuyler, Jay R. Hesselberth, Hugo R. Rosen, Matthew A. Burchill
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Liver lymphatic vessels support liver function by draining interstitial fluid, cholesterol, fat, and immune cells for surveillance in the liver draining lymph node. Chronic liver disease is associated with increased inflammation and immune cell infil
Externí odkaz:
https://doaj.org/article/d29ecb98b02b49bc805850487ed15d2d
Autor:
Peter S. Harris, Cole R. Michel, Youngho Yun, Courtney D. McGinnis, Mohammed A. Assiri, Ali Reza Ahmadi, Zhaoli Sun, James R. Roede, Matthew A. Burchill, David J. Orlicky, Rebecca L. McCullough, Kristofer S. Fritz
Publikováno v:
Alcohol
Alcohol consumption remains a leading cause of liver disease worldwide, resulting in a complex array of hepatic pathologies, including steatosis, steatohepatitis, and cirrhosis. Individuals who progress to a rarer form of alcohol-associated liver dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878abbfbf3cad980fcae14abcec55ac0
https://europepmc.org/articles/PMC8919678/
https://europepmc.org/articles/PMC8919678/
Autor:
Matthew A. Burchill, Hugo R. Rosen, Claudia Jakubzick, Rachel H. McMahan, Lin Ling Cheng, Prashanth Francis, Lucy Golden-Mason, David J. Orlicky, Brett McGettigan, Thomas Danhorn
Publikováno v:
Hepatology
A crucial component of nonalcoholic fatty liver disease (NAFLD) pathogenesis is lipid stress, which may contribute to hepatic inflammation and activation of innate immunity in the liver. However, little is known regarding how dietary lipids, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2d0fe386681fc8fc9d2073de282750
https://doi.org/10.1002/hep.30401
https://doi.org/10.1002/hep.30401
Autor:
Rui Fu, Johnathon Schafer, Shannon M Walsh, Beth A. Jirón Tamburini, Thu A Doan, Ryan M. Sheridan, Matthew A. Burchill, Jay R. Hesselberth, Brian C Ware, Erin D. Lucas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7662f6ee60ff21f237c0ec5bdfc1727d
https://doi.org/10.7554/elife.62781.sa2
https://doi.org/10.7554/elife.62781.sa2