Long-term health impacts of COVID-19 among 242,712 adults in England

Autor: Christina J. Atchison, Bethan Davies, Emily Cooper, Adam Lound, Matthew Whitaker, Adam Hampshire, Adriana Azor, Christl A. Donnelly, Marc Chadeau-Hyam, Graham S. Cooke, Helen Ward, Paul Elliott

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)

Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested posit

Externí odkaz: https://doaj.org/article/47dd447bfacb4350a0f1ef3faffd497a

Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England

Autor: Matthew Whitaker, Joshua Elliott, Barbara Bodinier, Wendy Barclay, Helen Ward, Graham Cooke, Christl A. Donnelly, Marc Chadeau-Hyam, Paul Elliott

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

In this study, the authors assess changing symptom profiles associated with different SARS-CoV-2 variants from May 2020 to March 2022 in England. Using data from the REACT-1 study, they find that Omicron infection is more often associated with cold a

Externí odkaz: https://doaj.org/article/49ef4a4c20114cb6a6311096e7fa0512

Machine learning to support visual auditing of home-based lateral flow immunoassay self-test results for SARS-CoV-2 antibodies

Autor: Nathan C. K. Wong, Sepehr Meshkinfamfard, Valérian Turbé, Matthew Whitaker, Maya Moshe, Alessia Bardanzellu, Tianhong Dai, Eduardo Pignatelli, Wendy Barclay, Ara Darzi, Paul Elliott, Helen Ward, Reiko J. Tanaka, Graham S. Cooke, Rachel A. McKendry, Christina J. Atchison, Anil A. Bharath

Publikováno v: Communications Medicine, Vol 2, Iss 1, Pp 1-10 (2022)

Wong et al. describe a machine learning approach for visual auditing of lateral flow tests for SARS-CoV-2 antibodies. Their automated analysis shows strong agreement with experts and consistently better performance than non-expert study participants

Externí odkaz: https://doaj.org/article/07b76ff56a8546e2bdfba18d8ae2889a

Population antibody responses following COVID-19 vaccination in 212,102 individuals

Autor: Helen Ward, Matthew Whitaker, Barnaby Flower, Sonja N. Tang, Christina Atchison, Ara Darzi, Christl A. Donnelly, Alexandra Cann, Peter J. Diggle, Deborah Ashby, Steven Riley, Wendy S. Barclay, Paul Elliott, Graham S. Cooke

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-6 (2022)

The authors present results from the REACT-2 study, a series of cross-sectional community surveys during the SARS-CoV-2 pandemic in England. They measure antibodies by self-administered lateral flow tests and describe antibody positivity by time sinc

Externí odkaz: https://doaj.org/article/65f1b908da8a4df9bcf5d98c1039e8a0

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

Autor: Emily Jefferson, Christian Cole, Shahzad Mumtaz, Samuel Cox, Thomas Charles Giles, Sam Adejumo, Esmond Urwin, Daniel Lea, Calum Macdonald, Joseph Best, Erum Masood, Gordon Milligan, Jenny Johnston, Scott Horban, Ipek Birced, Christopher Hall, Aaron S Jackson, Clare Collins, Sam Rising, Charlotte Dodsley, Jill Hampton, Andrew Hadfield, Roberto Santos, Simon Tarr, Vasiliki Panagi, Joseph Lavagna, Tracy Jackson, Antony Chuter, Jillian Beggs, Magdalena Martinez-Queipo, Helen Ward, Julie von Ziegenweidt, Frances Burns, Joanne Martin, Neil Sebire, Carole Morris, Declan Bradley, Rob Baxter, Anni Ahonen-Bishopp, Paul Smith, Amelia Shoemark, Ana M Valdes, Benjamin Ollivere, Charlotte Manisty, David Eyre, Stephanie Gallant, George Joy, Andrew McAuley, David Connell, Kate Northstone, Katie Jeffery, Emanuele Di Angelantonio, Amy McMahon, Mat Walker, Malcolm Gracie Semple, Jessica Mai Sims, Emma Lawrence, Bethan Davies, John Kenneth Baillie, Ming Tang, Gary Leeming, Linda Power, Thomas Breeze, Duncan Murray, Chris Orton, Iain Pierce, Ian Hall, Shamez Ladhani, Natalie Gillson, Matthew Whitaker, Laura Shallcross, David Seymour, Susheel Varma, Gerry Reilly, Andrew Morris, Susan Hopkins, Aziz Sheikh, Philip Quinlan

Publikováno v: Journal of Medical Internet Research, Vol 24, Iss 12, p e40035 (2022)

BackgroundCOVID-19 data have been generated across the United Kingdom as a by-product of clinical care and public health provision, as well as numerous bespoke and repurposed research endeavors. Analysis of these data has underpinned the United Kingd

Externí odkaz: https://doaj.org/article/54ca7e259fa5437b93518def8143ad8f