Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Matthew, Tredwell"'
Autor:
Thibault Gendron, Gianluca Destro, Natan J. W. Straathof, Jeroen B. I. Sap, Florian Guibbal, Charles Vriamont, Claire Caygill, John R. Atack, Andrew J. Watkins, Christopher Marshall, Rebekka Hueting, Corentin Warnier, Véronique Gouverneur, Matthew Tredwell
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Background Flumazenil (FMZ) is a functionally silent imidazobenzodiazepine which binds to the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A receptors (GABAARs). Positron Emission Tomography (PET) imagin
Externí odkaz:
https://doaj.org/article/5341d4ac0ec2446bab32fb0383e7b523
Autor:
Harriet Teare, Florian Huguet, Matthew Tredwell, Sébastien Thibaudeau, Sajinder K. Luthra, Véronique Gouverneur
Publikováno v:
ARKIVOC, Vol 2007, Iss 10, Pp 232-244 (2007)
Externí odkaz:
https://doaj.org/article/4dfa5431b87740d39effa59c72732ff6
Autor:
Matthew Tredwell
Publikováno v:
Synlett. 30:1371-1376
The synthesis of 18F-perfluorinated motifs from [18F]fluoride is a non-trivial undertaking as highlighted by the few methods and range of motifs that are known. In this Synpacts article we highlight our recent work on the synthesis and derivatization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bee608be8a9ff50ce8b7a5c51da6855
https://doi.org/10.1055/s-0037-1611764
https://doi.org/10.1055/s-0037-1611764
Publikováno v:
Angewandte Chemie International Edition. 58:472-476
A general method for the synthesis of 1,1‐[18F]difluorinated alkenes from [18F]fluoride is reported. This transformation is highly regioselective giving the desired 18F‐fluoroalkenes with radiochemical purities of up to 77 % within 20 minutes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0750503a1f240d34fd356d64ab10d4b1
https://doi.org/10.1002/anie.201810413
https://doi.org/10.1002/anie.201810413
Autor:
Adam, Nelson, Robert J, Phipps, Georgie J, Crane, Niccolo A E, Venanzi, William J S, Lockley, Matthew, Tredwell, Niklaas J, Buurma, Andrew, Ballard, Hiwa O, Ahmad, Stefania, Narduolo, Lucy, Rosa, Nikki, Chand, David A, Cosgrove, Peter, Varkonyi, Nabil, Asaad, Simone, Tomasi, Andrew G, Leach, Nick, Summerhill, Jon, Bloom, Mark, Newby, Stephen, Madden, Daniela, Roman, Ruediger M, Exner, Fernando, Cortezon-Tamarit, Haobo, Ge, Stephen, Paisey, Sofia I, Pascu, Rafael T M, de Rosales, Helen C, Hailes, Yu, Wang, Jianxiong, Zhao, Daniel, Méndez-Sánchez, Rebecca, Rodan, Fabiana, Subrizi, Benjamin R, Lichman, Nicholas H, Keep, John M, Ward, Mark, Harris, Martin, Lamb, Vernon, Wilson, Peter, Iafrate, Flaviu, Bulat, Andre A, Néves, Friederike, Hesse, De-En, Hu, Franklin, Aigbirhio, Finian J, Leeper, Kevin M, Brindle, Jack S, Rowbotham, Koji, Urata, Holly A, Reeve, Kylie A, Vincent, Rebekka, Hueting
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::888e0cb67bcb7d60a1f8334b4209196a
https://pubmed.ncbi.nlm.nih.gov/32678462
https://pubmed.ncbi.nlm.nih.gov/32678462
Autor:
Veerle Kersemans, Bart Cornelissen, Rebekka Hueting, Matthew Tredwell, Kamila Hussien, Philip D Allen, Nadia Falzone, Sally A Hill, Jonathan R Dilworth, Veronique Gouverneur, Ruth J Muschel, Sean C Smart
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e25911 (2011)
Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly alter experimental outcome. This study reports on the effects of both anaesthetic and carrier gas upon
Externí odkaz:
https://doaj.org/article/d94b7216c0104b6580d8720de7aaccac
Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands
Autor:
Matthew Tredwell, Michael Schedler, Christophe Genicot, Joël Mercier, Véronique Gouverneur, Sean Preshlock, Enrico Emer, Stefan Verhoog, Nicholas J. Taylor
Publikováno v:
Journal of the American Chemical Society. 139:8267-8276
Molecules labeled with fluorine-18 ((18)F) are used in positron emission tomography to visualize, characterize and measure biological processes in the body. Despite recent advances in the incorporation of (18)F onto arenes, the development of general
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f2bff7f0d7607e1d5c10c5af9d45ad
https://doi.org/10.1021/jacs.7b03131
https://doi.org/10.1021/jacs.7b03131
Publikováno v:
Chemical Reviews. 116:719-766
Diverse radiochemistry is an essential component of nuclear medicine; this includes imaging techniques such as positron emission tomography (PET). As such, PET can track diseases at an early stage of development, help patient care planning through pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5875b4df50bfada6524231a8b5d6160
https://doi.org/10.1021/acs.chemrev.5b00493
https://doi.org/10.1021/acs.chemrev.5b00493
Publikováno v:
Angewandte Chemie (International ed. in English). 58(2)
A general method for the synthesis of 1,1-[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c63b8725d751f56f53e8c9985c6da1e5
https://pubmed.ncbi.nlm.nih.gov/30452114
https://pubmed.ncbi.nlm.nih.gov/30452114
Autor:
Stefan Verhoog, Katherine Wheelhouse, Matthew Tredwell, Véronique Gouverneur, Lukas Pfeifer, Tanatorn Khotavivattana, Samuel Calderwood, Thomas Lee Collier
Publikováno v:
Synlett. 27:25-28
We report the synthesis of [18F]arylCF3 and [18F]arylCHF2 derivatives from arylCF2Br and arylCHFCl precursors applying a silver-mediated halogen exchange with [18F]fluoride. In the absence of Ag(I)OTf, no reaction takes place at room temperature for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b09c25c8108f3f925abff518dfb326
https://doi.org/10.1055/s-0035-1560592
https://doi.org/10.1055/s-0035-1560592