Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Matthew, Tegowski"'
Autor:
Matthew Tegowski, Kate D. Meyer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
A major mechanism of post-transcriptional RNA regulation in cells is the addition of chemical modifications to RNA nucleosides, which contributes to nearly every aspect of the RNA life cycle. N6-methyladenosine (m6A) is a highly prevalent modificatio
Externí odkaz:
https://doaj.org/article/fcc658d03be14e6b9eaa26a8f4c905a5
Autor:
Binta Jalloh, Carly L Lancaster, J Christopher Rounds, Brianna E Brown, Sara W Leung, Ayan Banerjee, Derrick J Morton, Rick S Bienkowski, Milo B Fasken, Isaac J Kremsky, Matthew Tegowski, Kate Meyer, Anita Corbett, Ken Moberg
Publikováno v:
eLife, Vol 12 (2023)
The Drosophila polyadenosine RNA binding protein Nab2, which is orthologous to a human protein lost in a form of inherited intellectual disability, controls adult locomotion, axon projection, dendritic arborization, and memory through a largely undef
Externí odkaz:
https://doaj.org/article/384aa69c3ab547f2ba8b015d5d5adbf5
Autor:
Matthew Tegowski, Kate D. Meyer
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101646- (2022)
Summary: Most techniques for mapping m6A-methylated RNAs transcriptome-wide require large amounts of RNA and have been limited to bulk cells and tissues. Here, we provide a detailed protocol for the identification of m6A sites in single HEK293T cells
Externí odkaz:
https://doaj.org/article/17f6131cef354fb8853d28ba38be0c29
Publikováno v:
Annual Review of Biochemistry. 92
Over the past decade, mRNA modifications have emerged as important regulators of gene expression control in cells. Fueled in large part by the development of tools for detecting RNA modifications transcriptome wide, researchers have uncovered a diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48460030ed1fc0f1972abb18711cc69
https://doi.org/10.1146/annurev-biochem-052521-035330
https://doi.org/10.1146/annurev-biochem-052521-035330
Autor:
Matthew, Tegowski, Kate D, Meyer
Publikováno v:
STAR protocols. 3(3)
Most techniques for mapping m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2d7a3d6b3361279a97140315de24c41
https://pubmed.ncbi.nlm.nih.gov/36042888
https://pubmed.ncbi.nlm.nih.gov/36042888
Autor:
Matthew Tegowski, Albert Baldwin
Publikováno v:
Biomedicines, Vol 6, Iss 2, p 66 (2018)
The NF-κB pathway is a critical regulator of immune responses and is often dysregulated in cancer. Two NF-κB pathways have been described to mediate these responses, the canonical and the noncanonical. While understudied compared to the canonical N
Externí odkaz:
https://doaj.org/article/d08d79d717c54119b2436006c840b77a
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618509
Recent studies have uncovered that cellular mRNAs contain a diverse epitranscriptome comprising chemically modified bases which play important roles in gene expression regulation. Among these is m6A, which is a highly prevalent modification that cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b9a04247db31dca7cb598d501f20b5
https://doi.org/10.1007/978-1-0716-1851-6_20
https://doi.org/10.1007/978-1-0716-1851-6_20
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2404
Recent studies have uncovered that cellular mRNAs contain a diverse epitranscriptome comprising chemically modified bases which play important roles in gene expression regulation. Among these is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2deadb239e233f24060913382b97f1f
https://pubmed.ncbi.nlm.nih.gov/34694620
https://pubmed.ncbi.nlm.nih.gov/34694620
Publikováno v:
Mol Cell
N(6)-methyladenosine (m(6)A) is an abundant RNA modification that plays critical roles in RNA regulation and cellular function. Global m(6)A profiling has revealed important aspects of m(6)A distribution and function, but to date such studies have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c71c6707824c24f8f846a20f337db53
https://doi.org/10.1016/j.molcel.2021.12.038
https://doi.org/10.1016/j.molcel.2021.12.038
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Several recent publications demonstrated that DRD2-targeting antipsychotics such as thioridazine induce proliferation arrest and apoptosis in diverse cancer cell types including those derived from brain, lung, colon, and breast. While most studies sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f10247327c82747c8a52e55d048260
https://doi.org/10.1038/s41598-019-55145-3
https://doi.org/10.1038/s41598-019-55145-3