Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthew, Hoekstra"'
Autor:
Matthew Hoekstra, Myron L. Smith
Publikováno v:
Polymers, Vol 15, Iss 11, p 2439 (2023)
We present a spectrophotometric-based assay to identify enzymes that degrade commercially available bioplastics. Bioplastics comprise aliphatic polyesters with hydrolysis-susceptible ester bonds and are proposed as a replacement for petroleum-based p
Externí odkaz:
https://doaj.org/article/9f203224ee854e20b0e0eef32de096d8
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101271- (2022)
Summary: Within the realm of lysine methylation, the discovery of lysine methyltransferase (KMTs) substrates has been burgeoning because of established systematic substrate screening protocols. Here, we describe a protocol enabling the systematic ide
Externí odkaz:
https://doaj.org/article/9388b4d5257446e1be75ad15f66f3108
Autor:
Kyle K. Biggar, Francois Charih, Huadong Liu, Yasser B. Ruiz-Blanco, Leanne Stalker, Anand Chopra, Justin Connolly, Hemanta Adhikary, Kristin Frensemier, Matthew Hoekstra, Marek Galka, Qi Fang, Christopher Wynder, William L. Stanford, James R. Green, Shawn S.-C. Li
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107896- (2020)
Summary: Protein Lys methylation plays a critical role in numerous cellular processes, but it is challenging to identify Lys methylation in a systematic manner. Here we present an approach combining in silico prediction with targeted mass spectrometr
Externí odkaz:
https://doaj.org/article/c0b58f3b2a5e4e07bf74498035653f50
Publikováno v:
The Journal of Biochemistry. 173:31-42
The KDM5/JARID1 sub-family are 2-oxoglutarate and Fe(II)-dependent lysine-specific histone demethylases that are characterized by their Jumonji catalytic domains. The KDM5 family is known to remove tri-/di-methyl modifications from lysine-4 of histon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3717f70209b3bb75b7e162d839da77a
https://doi.org/10.1093/jb/mvac081
https://doi.org/10.1093/jb/mvac081
Autor:
Anand, Chopra, Ali H, Shukri, Hemanta, Adhikary, Valentina, Lukinović, Matthew, Hoekstra, Michael, Cowpland, Kyle K, Biggar
Publikováno v:
Peptides. 158:170898
In humans, coronaviruses are the cause of endemic illness and have been the causative agents of more severe epidemics. Most recently, SARS-CoV-2 was the causative agent of the COVID19 pandemic. Thus, there is a high interest in developing therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81bc00b6670b166443dc056ac09ffeb
https://doi.org/10.1016/j.peptides.2022.170898
https://doi.org/10.1016/j.peptides.2022.170898
Autor:
Anand Chopra, Yasser B. Ruiz-Blanco, Kristin Frensemier, Christopher Wynder, William L. Stanford, Qi Fang, James R. Green, Huadong Liu, Matthew Hoekstra, Shawn S.-C. Li, Justin Connolly, Francois Charih, Marek Galka, Hemanta Adhikary, Leanne Stalker, Kyle K. Biggar
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107896-(2020)
Protein Lys methylation plays a critical role in numerous cellular processes, but it is challenging to identify Lys methylation in a systematic manner. Here we present an approach combining in silico prediction with targeted mass spectrometry (MS) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852cae297fca1f1a835690d646e88414
https://pubmed.ncbi.nlm.nih.gov/32668242
https://pubmed.ncbi.nlm.nih.gov/32668242
Autor:
Kyle K. Biggar, Matthew Hoekstra
Publikováno v:
Analytical Biochemistry. 633:114429
A major regulatory influence over gene expression is the dynamic post translational methylation of histone proteins, with major implications from both lysine methylation and demethylation. The KDM5/JARID1 sub-family of Fe(II)/2-oxoglutarate dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9685bfaf85a77988a7a1e8f409139ff
https://doi.org/10.1016/j.ab.2021.114429
https://doi.org/10.1016/j.ab.2021.114429