Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Matthew, Gardener"'
Autor:
Timothy O, Cox, Erik C, Gunther, A Harrison, Brody, Marius T, Chiasseu, Austin, Stoner, Levi M, Smith, Laura T, Haas, Jayne, Hammersley, Gareth, Rees, Bhupinder, Dosanjh, Maria, Groves, Matthew, Gardener, Claire, Dobson, Tristan, Vaughan, Iain, Chessell, Andrew, Billinton, Stephen M, Strittmatter
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Amyloid‐beta oligomers (Aßo) trigger the development of Alzheimer's disease (AD) pathophysiology. Cellular prion protein (PrPC) initiates synaptic damage as a high affinity receptor for Aßo. Here, we evaluated the preclinical therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d36f7f5c180265d45d862a4329636ad4
https://pubmed.ncbi.nlm.nih.gov/30911579
https://pubmed.ncbi.nlm.nih.gov/30911579
Autor:
Scott A. Maidment, Matthew Gardener, Simon Dowler, Anthony Lawrence, Tristana von Will, Andrew Southan, Gary Clark, Omar Aziz
Publikováno v:
Biophysical Journal. 96(3)
The KCNQ (Kv7) family of voltage gated ion channels conduct a number of hyperpolarising currents in various tissue types, including the heteromultimeric KCNQ2/3 M-current found in sensory neurones. Cell lines constructed using constitutive expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c590fa0d742dc77e3ee889ab51ee4eb8
Autor:
Rebecca Prime, Matthew Gardener, Andrew Southan, Scott A. Maidment, Tristana von Will, Steven England, Gary Clark, Edward Stevens, Elizabeth Payne
Publikováno v:
Biophysical Journal. (3):672a
The advent of high-throughput electrophysiology utilizing Population Patch Clamp™ (PPC) technology has allowed the screening of large compound libraries against ion channels representing novel targets in a variety of disease states. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9ef07679a52bdbecd3ad0649597c09