Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Matthew, Cook"'
Autor:
Tergel Namsrai, Christine Phillips, Anne Parkinson, Dianne Gregory, Elaine Kelly, Matthew Cook, Jane Desborough
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Sarcoidosis is a chronic inflammatory granulomatous disease of unknown cause. Delays in diagnosis can result in disease progression and poorer outcomes for patients. Our aim was to review the current literature to determine the ov
Externí odkaz:
https://doaj.org/article/24aa4eefbb884d0687d3042d42b87413
Autor:
Sarah E. Garnish, Katherine R. Martin, Maria Kauppi, Victoria E. Jackson, Rebecca Ambrose, Vik Ven Eng, Shene Chiou, Yanxiang Meng, Daniel Frank, Emma C. Tovey Crutchfield, Komal M. Patel, Annette V. Jacobsen, Georgia K. Atkin-Smith, Ladina Di Rago, Marcel Doerflinger, Christopher R. Horne, Cathrine Hall, Samuel N. Young, Matthew Cook, Vicki Athanasopoulos, Carola G. Vinuesa, Kate E. Lawlor, Ian P. Wicks, Gregor Ebert, Ashley P. Ng, Charlotte A. Slade, Jaclyn S. Pearson, André L. Samson, John Silke, James M. Murphy, Joanne M. Hildebrand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Across the globe, 2-3% of humans carry the p.Ser132Pro single nucleotide polymorphism in MLKL, the terminal effector protein of the inflammatory form of programmed cell death, necroptosis. Here we show that this substitution confers a gain i
Externí odkaz:
https://doaj.org/article/14198b0aa4ad4e93a3c3095f5a9f9cb4
Autor:
Mario Sestan, Nastasia Kifer, Todor Arsov, Matthew Cook, Julia Ellyard, Carola G. Vinuesa, Marija Jelusic
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5981-6002 (2023)
The pathogenesis of childhood-onset systemic lupus erythematosus (cSLE) is complex and not fully understood. It involves three key factors: genetic risk factors, epigenetic mechanisms, and environmental triggers. Genetic factors play a significant ro
Externí odkaz:
https://doaj.org/article/f8311bdd298e4541989c1f191532cbb3
Autor:
Yi Tong V. Aw, Phillip J. Whiley, Ayla May Lorenzo, Tom Lea‐Henry, Somasundhari Shanmuganandam, Maurice Stanley, Sonia N. Babu, Vicki Athanasopoulos, Jean Cappello, Julia I. Ellyard, Matthew Cook, Carola Vinuesa, Giles Walters, David A. Fulcher, Simon H. Jiang
Publikováno v:
Rheumatology & Autoimmunity, Vol 3, Iss 1, Pp 15-25 (2023)
Abstract Background Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan involvement. Kidney involvement, termed lupus nephritis, has major impact on life expectancy
Externí odkaz:
https://doaj.org/article/cd66a9875c2c49ef8bb932bfc96e6597
Publikováno v:
Journal of Integrative Environmental Sciences, Vol 19, Iss 1, Pp 209-225 (2022)
ABSTRACTTo help move society towards more sustainable states, policies have been developed in various countries to create a circular bioeconomy (CBE) in biobased sectors such as forestry and agriculture. In operationalizing CBE, initiatives must be c
Externí odkaz:
https://doaj.org/article/de42f4f14ab44a50b4bf12ed493c98dd
Autor:
Tergel Namsrai, Anne Parkinson, Anita Chalmers, Christine Lowe, Matthew Cook, Christine Phillips, Jane Desborough
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract Background Idiopathic inflammatory myopathies (IIM) are a heterogenous group of rare muscular autoimmune diseases characterised by skeletal muscle inflammation with possible diagnostic delay. Our aim was to review the existing evidence to id
Externí odkaz:
https://doaj.org/article/2ff2a7a03c3f4ad78be00defe5e09423
Autor:
Jun Yen Ng, Meidelynn Ooi, Samuel Bennett, Kirsty Rady, Philip Choi, Wei-I Lee, Matthew Cook, Katrina Randall, Nalini Pati
Publikováno v:
HemaSphere, Vol 7, p e9281279 (2023)
Externí odkaz:
https://doaj.org/article/9e93c5fc1b4142b9846312db5db14cd2
Autor:
Matthew Cook, Ben Stevenson, Laura A. Jacobs, Daniel Leocadio Victoria, Bulmaro Cisneros, Jamie K. Hobbs, Colin L. Stewart, Steve J. Winder
Publikováno v:
Cells, Vol 13, Iss 5, p 431 (2024)
Dystroglycan is a ubiquitously expressed heterodimeric cell-surface laminin receptor with roles in cell adhesion, signalling, and membrane stabilisation. More recently, the transmembrane β-subunit of dystroglycan has been shown to localise to both t
Externí odkaz:
https://doaj.org/article/04576a76b1c445ed86dab1d4022de61c
Autor:
Miguel Valdez, Matthew Cook
Publikováno v:
Frontiers in Sustainable Cities, Vol 5 (2023)
Autonomous urban robots were introduced in Milton Keynes (MK), UK, in 2018 to automate on-demand grocery delivery. Two years later the COVID-19 pandemic rendered routine activities such as delivering groceries or visiting the supermarket unexpectedly
Externí odkaz:
https://doaj.org/article/599294a11a6543139a93c3887e7ec2aa
Autor:
Lei Peng, Yingxia Hu, Madeleine C. Mankowski, Ping Ren, Rita E. Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D. Chow, Zhenhao Fang, Chunxiang Wu, Matthew B. Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl Klein, Richard Sutton, Michael S. Diamond, Craig B. Wilen, Yong Xiong, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Despite effective vaccines against SARS-CoV-2, therapeutic options such as anti-virals and neutralizing antibodies are critical in treating disease, especially given the breakthrough infections of emerging VOCs. Here, Peng et al. generate two potent
Externí odkaz:
https://doaj.org/article/3c2da467436042e1868fd384b454c96c