Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Matthew, Burge"'
Autor:
Marjan M. Naeini, Felicity Newell, Lauren G. Aoude, Vanessa F. Bonazzi, Kalpana Patel, Guy Lampe, Lambros T. Koufariotis, Vanessa Lakis, Venkateswar Addala, Olga Kondrashova, Rebecca L. Johnston, Sowmya Sharma, Sandra Brosda, Oliver Holmes, Conrad Leonard, Scott Wood, Qinying Xu, Janine Thomas, Euan Walpole, G. Tao Mai, Stephen P. Ackland, Jarad Martin, Matthew Burge, Robert Finch, Christos S. Karapetis, Jenny Shannon, Louise Nott, Robert Bohmer, Kate Wilson, Elizabeth Barnes, John R. Zalcberg, B. Mark Smithers, John Simes, Timothy Price, Val Gebski, Katia Nones, David I. Watson, John V. Pearson, Andrew P. Barbour, Nicola Waddell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Oesophageal adenocarcinoma is a poor prognosis cancer and the molecular features underpinning response to treatment remain unclear. We investigate whole genome, transcriptomic and methylation data from 115 oesophageal adenocarcinoma patients
Externí odkaz:
https://doaj.org/article/10a795104a0f4275aaca1728299e2389
Autor:
Matthew Burge, David Goldstein, Andrew Haydon, Nick Pavlakis, Charlotte Lemech, Edward Hammond, Darryn Bampton, Keith Dredge, Michael P Brown, Andrew Clouston, Nigel J Waterhouse, Amanda C Stanley, Lucie Leveque-El Mouttie, Grace M Chojnowski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Pixatimod is a unique activator of the Toll-like Receptor 9 pathway. This phase I trial evaluated safety, efficacy and pharmacodynamics of pixatimod and PD-1 inhibitor nivolumab in immunologically cold cancers.Methods 3+3 dose escalation w
Externí odkaz:
https://doaj.org/article/9084358ebd5841eb853afac834f15155
Autor:
Ho Wai Derrick Siu, Niall Tebbutt, Lorraine Chantrill, Chris Karapetis, Christopher Steer, Kate Wilson, David Espinoza, Lisa Bailey, Sonia Yip, Jeff Cuff, Nick Pavlakis, Subotheni Thavaneswaran, Karen Briscoe, Ratnesh Srivastav, Jennifer Shannon, Eva Segelov, Jeannie Tie, Susan Caird, Alessandra Francesconi, Timothy Price, Melanie Wuttke, Rahul Ladwa, Katrin Sjoquist, Matthew Burge
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Doublet chemotherapy in combination with a biologic agent has been a standard of care in patients with metastatic colorectal cancer for over a decade. The evidence for a “lighter” treatment approach is limited to mono-chemothe
Externí odkaz:
https://doaj.org/article/fde8f6085457444da73ce4c379983bf2
Autor:
Matthew Burge, David Goldstein, Andrew Haydon, Nick Pavlakis, Michael Brown, Charlotte Lemech, Edward Hammond, Darryn Bampton, Keith Dredge, Amanda Stanley, Lucie Leveque-ElMouttie, Grace Chojnowski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/707ab3742ab34661a168c0e1852c01c0
Autor:
Matthew Burge, David Goldstein, Andrew Haydon, Nick Pavlakis, Michael Brown, Charlotte Lemech, Edward Hammond, Darryn Bampton, Keith Dredge, Nigel Waterhouse, Amanda Stanley, Lucie Leveque-ElMouttie, Grace Chojnowski, Andrew Clouson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/28156c09a15e41f3a51704b1a003571b
Autor:
Dung T. Le, Luis A. Diaz, Tae Won Kim, Eric Van Cutsem, Ravit Geva, Dirk Jäger, Hiroki Hara, Matthew Burge, Bert H. O’Neil, Petr Kavan, Takayuki Yoshino, Rosine Guimbaud, Hiroya Taniguchi, Elena Élez, Salah-Eddin Al-Batran, Patrick M. Boland, Yi Cui, Pierre Leconte, Patricia Marinello, Thierry André
Publikováno v:
European Journal of Cancer. 186:185-195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1345b3ef9062bdf742803f8d06e925
https://doi.org/10.1016/j.ejca.2023.02.016
https://doi.org/10.1016/j.ejca.2023.02.016
Autor:
Jeanne Tie, Yuxuan Wang, Joshua Cohen, Lu Li, Wei Hong, Michael Christie, Hui Li Wong, Suzanne Kosmider, Rachel Wong, Benjamin Thomson, Julian Choi, Adrian Fox, Kathryn Field, Matthew Burge, Jenny Shannon, Dusan Kotasek, Niall C Tebbutt, Christos Karapetis, Craig Underhill, Andrew Haydon, Joy Schaeffer, Janine Ptak, Cristian Tomasetti, Nicholas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs
Publikováno v:
PLoS Medicine, Vol 18, Iss 5, p e1003620 (2021)
BackgroundIn patients with resectable colorectal liver metastases (CRLM), the role of pre- and postoperative systemic therapy continues to be debated. Previous studies have shown that circulating tumor DNA (ctDNA) analysis, as a marker of minimal res
Externí odkaz:
https://doaj.org/article/5fefae544f494349b57c0bd567ac52e2
Autor:
Stephen John Clarke, Matthew Burge, Kynan Feeney, Peter Gibbs, Kristian Jones, Gavin Marx, Mark P Molloy, Timothy Price, William H H Reece, Eva Segelov, Niall C Tebbutt
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229900 (2020)
BackgroundIn spite of demonstrating prognostic and possibly predictive benefit in retrospective cohorts and meta-analyses of cancer populations, including colorectal cancer (CRC), prospective evaluation of the relationship between neutrophil to lymph
Externí odkaz:
https://doaj.org/article/cd2703a957b846b1ba3c1198c841daa4
Autor:
Caroline Even, Jean-Pierre Delord, Katharine A. Price, Kazuhiko Nakagawa, Do-Youn Oh, Matthew Burge, Hyun C. Chung, Toshihiko Doi, Marwan Fakih, Shunji Takahashi, Lili Yao, Fan Jin, Kevin Norwood, Aaron R. Hansen
Publikováno v:
European Journal of Cancer. 171:259-268
We evaluated pembrolizumab monotherapy in patients with advanced salivary gland carcinoma on the phase 2 KEYNOTE-158 study (NCT02628067).Eligible patients had histologically/cytologically confirmed advanced salivary gland carcinoma with prior failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de46481e7bf78962e866ce2ee6e5910
https://doi.org/10.1016/j.ejca.2022.05.007
https://doi.org/10.1016/j.ejca.2022.05.007
Autor:
Ronnie, Shapira-Frommer, Linda, Mileshkin, Ludmila, Manzyuk, Nicolas, Penel, Matthew, Burge, Sarina A, Piha-Paul, Eugenia, Girda, Jose A, Lopez Martin, Marloes G J, van Dongen, Antoine, Italiano, Lei, Xu, Fan, Jin, Kevin, Norwood, Patrick A, Ott
Publikováno v:
Gynecologic Oncology. 166:211-218
Treatment options for advanced vulvar cancer are limited. We evaluated pembrolizumab monotherapy in patients with advanced vulvar squamous cell carcinoma (SCC) enrolled in the phase 2 multicohort, open-label KEYNOTE-158 study (NCT02628067).Eligible p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff879be975f92a7aef83a31143b2313
https://doi.org/10.1016/j.ygyno.2022.01.029
https://doi.org/10.1016/j.ygyno.2022.01.029