Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Matthaeus Schwarz-Schilling"'
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0198058 (2018)
CRISPR interference (CRISPRi) using dCas9-sgRNA is a powerful tool for the exploration and manipulation of gene functions. Here we quantify the reversible switching of a central process of the bacterial cell cycle by CRISPRi and an antisense RNA mech
Externí odkaz:
https://doaj.org/article/c87416c5f18b420e8c13c527664e07ab
Autor:
Joaquin A. M. Guttierez, Friedrich C. Simmel, John Henningsen, Sandra Sagredo, Andreas Leibl, Matthaeus Schwarz-Schilling
Publikováno v:
ACS Synthetic BIology
Genetic networks that generate oscillations in gene expression activity are found in a wide range of organisms throughout all kingdoms of life. Oscillatory dynamics facilitates the temporal orchestration of metabolic and growth processes inside cells
Publikováno v:
ACS Synthetic Biology
Gene regulation based on regulatory RNA is an important mechanism in cells and is increasingly used for regulatory circuits in synthetic biology. Toehold switches are rationally designed post-transcriptional riboregulators placed in the 5’ untransl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eba7faeb842313ea2cafc844524cd5
https://doi.org/10.1101/2021.09.29.462367
https://doi.org/10.1101/2021.09.29.462367
Autor:
Matthaeus Schwarz-Schilling, Friedrich C. Simmel, Günther Pardatscher, Roy Bar-Ziv, Shirley S. Daube
Publikováno v:
Angewandte Chemie. 130:4873-4876
CRISPR interference (CRISPRi) using dCas9/sgRNA is a powerful tool for the exploration and manipulation of gene functions. Here we quantify the reversible switching of crucial cellular processes by CRISPRi and an antisense RNA mechanism. Reversible i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccaf49778e3a87f6f1f1d7fc8c26932
Autor:
Matthaeus Schwarz-Schilling, Swati Krishnan, Aurore Dupin, Sheref S. Mansy, Friedrich C. Simmel, Fabio Chizzolini
Publikováno v:
Nano letters. 18(4)
Molecular complexes composed of RNA molecules and proteins are promising multifunctional nanostructures for a wide variety of applications in biological cells or in artificial cellular systems. In this study, we systematically address some of the cha
Autor:
Shirley S. Daube, Friedrich C. Simmel, Roy Bar-Ziv, Günther Pardatscher, Matthaeus Schwarz-Schilling
Publikováno v:
Angewandte Chemie (International ed. in English). 57(17)
Lithographic patterning of DNA molecules enables spatial organization of cell-free genetic circuits under well-controlled experimental conditions. Here, we present a biocompatible, DNA-based resist termed "Bephore", which is based on commercially ava
Publikováno v:
Journal of Visualized Experiments
J Vis Exp
J Vis Exp
Immobilization of genes on lithographically structured surfaces allows the study of compartmentalized gene expression processes in an open microfluidic bioreactor system. In contrast to other approaches towards artificial cellular systems, such a set
Autor:
Matthaeus Schwarz-Schilling, Swati Krishnan, Aurore Dupin, Friedrich C. Simmel, Sheref S. Mansy, Fabio Chizzolini
Publikováno v:
Nano Letters. 19:4812-4812
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 8(4)
Position-dependent gene expression in gradients of morphogens is one of the key processes involved in cellular differentiation during development. Here, we study a simple artificial differentiation process, which is based on the diffusion of genetic