Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Matteo Tiberti"'
Autor:
Kenneth Bødkter Schou, Samuel Mandacaru, Muhammad Tahir, Nikola Tom, Ann-Sofie Nilsson, Jens S. Andersen, Matteo Tiberti, Elena Papaleo, Jiri Bartek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Evolutionary annotation of genome maintenance (GM) proteins has conventionally been established by remote relationships within protein sequence databases. However, often no significant relationship can be established. Highly sensitive approa
Externí odkaz:
https://doaj.org/article/ed9404b41a5247c598c3a1a88d6e56f2
Autor:
Elena Papaleo, Matteo Tiberti, Matteo Arnaudi, Chiara Pecorari, Fiorella Faienza, Lisa Cantwell, Kristine Degn, Francesca Pacello, Andrea Battistoni, Matteo Lambrughi, Giuseppe Filomeni
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-19 (2023)
Abstract S-nitrosylation is a post-translational modification in which nitric oxide (NO) binds to the thiol group of cysteine, generating an S-nitrosothiol (SNO) adduct. S-nitrosylation has different physiological roles, and its alteration has also b
Externí odkaz:
https://doaj.org/article/231b05c6fe294700a44ea7fd0b19bdbf
Autor:
Matteo Tiberti, Luca Di Leo, Mette Vixø Vistesen, Rikke Sofie Kuhre, Francesco Cecconi, Daniela De Zio, Elena Papaleo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-12 (2022)
Abstract Cancer genomics and cancer mutation databases have made an available wealth of information about missense mutations found in cancer patient samples. Contextualizing by means of annotation and predicting the effect of amino acid change help i
Externí odkaz:
https://doaj.org/article/1a5bff2d7ac64ff5a3dfe6b370d30618
Autor:
Simone Scrima, Matteo Tiberti, Alessia Campo, Elisabeth Corcelle-Termeau, Delphine Judith, Mads Møller Foged, Knut Kristoffer Bundgaard Clemmensen, Sharon A. Tooze, Marja Jäättelä, Kenji Maeda, Matteo Lambrughi, Elena Papaleo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3604-3614 (2022)
Cellular membranes are formed from different lipids in various amounts and proportions depending on the subcellular localization. The lipid composition of membranes is sensitive to changes in the cellular environment, and its alterations are linked t
Externí odkaz:
https://doaj.org/article/d9a9f31068f941adb5b21143b5fbe8c7
Autor:
Valentina Sora, Mukesh Kumar, Emiliano Maiani, Matteo Lambrughi, Matteo Tiberti, Elena Papaleo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Autophagy is a conserved and essential intracellular mechanism for the removal of damaged components. Since autophagy deregulation is linked to different kinds of pathologies, it is fundamental to gain knowledge on the fine molecular and structural d
Externí odkaz:
https://doaj.org/article/52e1563adfe240beabadb491bb855689
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Nitric oxide (NO) plays an essential role in redox signaling in normal and pathological cellular conditions. In particular, it is well known to react in vivo with cysteines by the so-called S-nitrosylation reaction. S-nitrosylation is a selective and
Externí odkaz:
https://doaj.org/article/5e7ecd6c3de84f949da5cb00b3a441eb
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 11, p e1005826 (2017)
New promising avenues for the pharmacological treatment of skeletal and heart muscle diseases rely on direct sarcomeric modulators, which are molecules that can directly bind to sarcomeric proteins and either inhibit or enhance their activity. A rece
Externí odkaz:
https://doaj.org/article/9f961ec8e2a040438d68e59d3c8c6066
Autor:
Davide Michetti, Bjørn Olav Brandsdal, Davide Bon, Geir Villy Isaksen, Matteo Tiberti, Elena Papaleo
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0169586 (2017)
The psychrophilic and mesophilic endonucleases A (EndA) from Aliivibrio salmonicida (VsEndA) and Vibrio cholera (VcEndA) have been studied experimentally in terms of the biophysical properties related to thermal adaptation. The analyses of their stat
Externí odkaz:
https://doaj.org/article/23cd72f0154344eb86573bf533151c35
Autor:
Mads Nygaard, Thilde Terkelsen, Andre Vidas Olsen, Valentina Sora, Juan Salamanca Viloria, Fabio Rizza, Sanne Bergstrand, Miriam Di Marco, Mette Vistesen, Matteo Tiberti, Matteo Lambrughi, Marja Jaattela, Tuula Kallunki, Elena Papaleo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
SCAN domains in zinc-finger transcription factors are crucial mediators of protein-protein interactions. Up to 240 SCAN-domain encoding genes have been identified throughout the human genome. These include cancer-related genes, such as the myeloid zi
Externí odkaz:
https://doaj.org/article/58dd34e672cd4b8eaff4ee0795ada1e1
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004415 (2015)
There is increasing evidence that protein dynamics and conformational changes can play an important role in modulating biological function. As a result, experimental and computational methods are being developed, often synergistically, to study the d
Externí odkaz:
https://doaj.org/article/6604db76119d46b18991c24b3e4b2f28